Comet-like Heterodimers “Gold Nanoflower @Graphene Quantum Dots” Probe with FRET “Off” to DNA Circuit Signal “On” for Sensing and Imaging MicroRNA In Vitro and In Vivo

2018 ◽  
Vol 90 (19) ◽  
pp. 11538-11547 ◽  
Author(s):  
Jiadi Sun ◽  
Fangchao Cui ◽  
Ruyuan Zhang ◽  
Zhixian Gao ◽  
Jian Ji ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots

(Invited) In Vitro and In Vivo Near-Infrared Imaging with Biocompatible Bottom-up and Top-Down-Synthesized Graphene Quantum Dots

2020 ◽  
Vol MA2020-01 (6) ◽  
pp. 648-648
Author(s):  
Anton V Naumov ◽  
Md Tanvir Hasan ◽  
Elizabeth Campbell ◽  
Ching-Wei Lin ◽  
Angela M. Belcher
Keyword(s):  
Quantum Dots ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Graphene Quantum Dots ◽  
Top Down ◽  
Near Infrared Imaging ◽  
Bottom Up

GFP Plasmid and Chemoreagent Conjugated with Graphene Quantum Dots as a Novel Gene Delivery Platform for Colon Cancer Inhibition In Vitro and In Vivo

2020 ◽  
Vol 3 (9) ◽  
pp. 5948-5956
Author(s):  
Pei-Ying Lo ◽  
Guang-Yu Lee ◽  
Jia-Huei Zheng ◽  
Jen-Hsien Huang ◽  
Er-Chieh Cho ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Quantum Dots ◽  
Gene Delivery ◽  
Graphene Quantum Dots ◽  
Novel Gene ◽  
Delivery Platform ◽  
Cancer Inhibition

scholarly journals Loading Graphene Quantum Dots into Optical-Magneto Nanoparticles for Real-Time Tracking In Vivo

Materials ◽  
2019 ◽  
Vol 12 (13) ◽  
pp. 2191 ◽  
Author(s):  
Yu Wang ◽  
Nan Xu ◽  
Yongkai He ◽  
Jingyun Wang ◽  
Dan Wang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Real Time ◽  
Fluorescent Dyes ◽  
Graphene Quantum Dots ◽  
Shell Nanoparticles ◽  
One Pot ◽  
Real Time Tracking

Fluorescence imaging offers a new approach to visualize real-time details on a cellular level in vitro and in vivo without radioactive damage. Poor light stability of organic fluorescent dyes makes long-term imaging difficult. Due to their outstanding optical properties and unique structural features, graphene quantum dots (GQDs) are promising in the field of imaging for real-time tracking in vivo. At present, GQDs are mainly loaded on the surface of nanoparticles. In this study, we developed an efficient and convenient one-pot method to load GQDs into nanoparticles, leading to longer metabolic processes in blood and increased delivery of GQDs to tumors. Optical-magneto ferroferric oxide@polypyrrole (Fe3O4@PPy) core-shell nanoparticles were chosen for their potential use in cancer therapy. The in vivo results demonstrated that by loading GQDs, it was possible to monitor the distribution and metabolism of nanoparticles. This study provided new insights into the application of GQDs in long-term in vivo real-time tracking.

scholarly journals Fabrication of highly fluorescent graphene quantum dots using l-glutamic acid for in vitro/in vivo imaging and sensing

2013 ◽  
Vol 1 (31) ◽  
pp. 4676 ◽  
Author(s):  
Xu Wu ◽  
Fei Tian ◽  
Wenxue Wang ◽  
Jiao Chen ◽  
Min Wu ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Glutamic Acid ◽  
In Vivo Imaging ◽  
Graphene Quantum Dots

Near-infrared emitting graphene quantum dots synthesized from reduced graphene oxide for in vitro/in vivo/ex vivo bioimaging applications

2D Materials ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 035013
Author(s):  
Md Tanvir Hasan ◽  
Bong Han Lee ◽  
Ching-Wei Lin ◽  
Ainsley McDonald-Boyer ◽  
Roberto Gonzalez-Rodriguez ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Near Infrared ◽  
Ex Vivo ◽  
Graphene Quantum Dots ◽  
Reduced Graphene

The in vitro and in vivo toxicity of graphene quantum dots

Biomaterials ◽  
2014 ◽  
Vol 35 (19) ◽  
pp. 5041-5048 ◽  
Author(s):  
Yu Chong ◽  
Yufei Ma ◽  
He Shen ◽  
Xiaolong Tu ◽  
Xuan Zhou ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
In Vivo Toxicity

scholarly journals Graphene quantum dots: From efficient preparation to safe renal excretion

Nano Research ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 674-683
Author(s):  
Caroline Hadad ◽  
José Miguel González-Domínguez ◽  
Silvia Armelloni ◽  
Deborah Mattinzoli ◽  
Masami Ikehata ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Carbon Nanomaterials ◽  
Renal Excretion ◽  
Graphene Quantum Dots ◽  
Aqueous Solubility ◽  
Therapeutic Agents ◽  
Internalization Mechanism ◽  
Good Biocompatibility

AbstractCarbon nanomaterials offer excellent prospects as therapeutic agents, and among them, graphene quantum dots (GQDs) have gained considerable interest thanks to their aqueous solubility and intrinsic fluorescence, which enable their possible use in theranostic approaches, if their biocompatibility and favorable pharmacokinetic are confirmed. We prepared ultra-small GQDs using an alternative, reproducible, top-down synthesis starting from graphene oxide with a nearly 100% conversion. The materials were tested to assess their safety, demonstrating good biocompatibility and ability in passing the ultrafiltration barrier using an in vitro model. This leads to renal excretion without affecting the kidneys. Moreover, we studied the GQDs in vivo biodistribution confirming their efficient renal clearance, and we demonstrated that the internalization mechanism into podocytes is caveolae-mediated. Therefore, considering the reported characteristics, it appears possible to vehiculate compounds to kidneys by means of GQDs, overcoming problems related to lysosomal degradation.

(Invited) In Vitro and In Vivo Near-Infrared Imaging with Biocompatible Bottom-up and Top-Down-Synthesized Graphene Quantum Dots

2021 ◽  
Vol MA2021-01 (10) ◽  
pp. 534-534
Author(s):  
Anton V. Naumov ◽  
Md. Tanvir Hasan ◽  
Ching-Wei Lin ◽  
Angela Belcher ◽  
Jeffery Coffer ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Graphene Quantum Dots ◽  
Top Down ◽  
Near Infrared Imaging ◽  
Bottom Up

Rare‐Earth Metal Ions Doped Graphene Quantum Dots for Near‐IR In Vitro/In Vivo/Ex Vivo Imaging Applications

2020 ◽  
Vol 8 (21) ◽  
pp. 2000897 ◽  
Author(s):  
Md. Tanvir Hasan ◽  
Roberto Gonzalez‐Rodriguez ◽  
Ching‐Wei Lin ◽  
Elizabeth Campbell ◽  
Satvik Vasireddy ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Rare Earth ◽  
Ex Vivo ◽  
Graphene Quantum Dots ◽  
Earth Metal ◽  
Near Ir ◽  
Doped Graphene ◽  
Ex Vivo Imaging

Integration of PEG and PEI with graphene quantum dots to fabricate pH-responsive nanostars for colon cancer suppression in vitro and in vivo

FlatChem ◽  
2021 ◽  
pp. 100320
Author(s):  
Guang-Yu Lee ◽  
Pei-Ying Lo ◽  
Er-Chieh Cho ◽  
Jia-Huei Zheng ◽  
Min Li ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Quantum Dots ◽  
Graphene Quantum Dots ◽  
Ph Responsive ◽  
Cancer Suppression
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