scholarly journals Coupled As and Mn Redox Transformations in an Fe(0) Electrocoagulation System: Competition for Reactive Oxidants and Sorption Sites

2020 ◽  
Vol 54 (12) ◽  
pp. 7165-7174
Author(s):  
Charlotte Catrouillet ◽  
Sachiko Hirosue ◽  
Nathalie Manetti ◽  
Victor Boureau ◽  
Jasquelin Peña
Keyword(s):  
Redox Transformations ◽  
Reactive Oxidants

Oxidase Catalysis via an Aerobically Generated Dess-Martin Periodinane Analogue

2018 ◽  
Author(s):  
Asim Maity ◽  
Sung-Min Hyun ◽  
Alan Wortman ◽  
David Powers
Keyword(s):  
Chemical Synthesis ◽  
Aerobic Oxidation ◽  
Substrate Oxidation ◽  
Oxidation Catalysis ◽  
Hypervalent Iodine ◽  
Oxidation Reactions ◽  
Broad Array ◽  
Oxidation Chemistry ◽  
Reactive Oxidants

<p>Hypervalent iodine(V) reagents, such as Dess-Martin periodinane (DMP) and 2-iodoxybenzoic acid (IBX), are broadly useful oxidants in chemical synthesis. Development of strategies to access these reagents from O2 would immediately enable use of O2 as a terminal oxidant in a broad array of substrate oxidation reactions. Recently we disclosed the aerobic synthesis of I(III) reagents by intercepting reactive oxidants generated during aldehyde autoxidation. Here, we couple aerobic oxidation of iodobenzenes with disproportionation of the initially generated I(III) compounds to generate I(V) reagents. The aerobically generated I(V) reagents exhibit substrate oxidation chemistry analogous to that of DMP. Further, the developed aerobic generation of I(V) has enabled the first application of I(V) intermediates in aerobic oxidation catalysis.</p>

scholarly journals Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Xueying Wang ◽  
Yanbin Feng ◽  
Xiaojia Guo ◽  
Qian Wang ◽  
Siyang Ning ◽  
...  
Keyword(s):  
Biological Sciences ◽  
Escherichia Coli ◽  
Nicotinamide Adenine Dinucleotide ◽  
Chemical Biology ◽  
Reduced Form ◽  
Redox Transformations ◽  
Nicotinamide Mononucleotide ◽  
Self Sufficiency ◽  
Binding Pockets ◽  
Pathway Regulation

AbstractNicotinamide adenine dinucleotide (NAD) and its reduced form are indispensable cofactors in life. Diverse NAD mimics have been developed for applications in chemical and biological sciences. Nicotinamide cytosine dinucleotide (NCD) has emerged as a non-natural cofactor to mediate redox transformations, while cells are fed with chemically synthesized NCD. Here, we create NCD synthetase (NcdS) by reprograming the substrate binding pockets of nicotinic acid mononucleotide (NaMN) adenylyltransferase to favor cytidine triphosphate and nicotinamide mononucleotide over their regular substrates ATP and NaMN, respectively. Overexpression of NcdS alone in the model host Escherichia coli facilitated intracellular production of NCD, and higher NCD levels up to 5.0 mM were achieved upon further pathway regulation. Finally, the non-natural cofactor self-sufficiency was confirmed by mediating an NCD-linked metabolic circuit to convert L-malate into D-lactate. NcdS together with NCD-linked enzymes offer unique tools and opportunities for intriguing studies in chemical biology and synthetic biology.

Redox transformations in desorption electrospray ionization

2009 ◽  
Vol 280 (1-3) ◽  
pp. 235-240 ◽  
Author(s):  
Mario Benassi ◽  
Chunping Wu ◽  
Marcela Nefliu ◽  
Demian R. Ifa ◽  
Michael Volný ◽  
...  
Keyword(s):  
Electrospray Ionization ◽  
Desorption Electrospray Ionization ◽  
Redox Transformations

Reversible Redox Transformations of Bridging Sulfide Ligands within Bioctahedral Rhenium Cluster Anions

2016 ◽  
Vol 2016 (25) ◽  
pp. 4066-4075 ◽  
Author(s):  
Yakov M. Gayfulin ◽  
Anton I. Smolentsev ◽  
Lyudmila V. Yanshole ◽  
Svetlana G. Kozlova ◽  
Yuri V. Mironov
Keyword(s):  
Cluster Anions ◽  
Redox Transformations ◽  
Reversible Redox ◽  
Sulfide Ligands ◽  
Rhenium Cluster

scholarly journals Do Vicinal Disulfide Bridges Mediate Functionally Important Redox Transformations in Proteins?

2013 ◽  
Vol 19 (16) ◽  
pp. 1976-1980 ◽  
Author(s):  
Aline Dantas de Araujo ◽  
Volker Herzig ◽  
Monique J. Windley ◽  
Sławomir Dziemborowicz ◽  
Mehdi Mobli ◽  
...  
Keyword(s):  
Disulfide Bridges ◽  
Redox Transformations

Synthesis and redox reactions of bis(verdazyl)palladium complexes

2017 ◽  
Vol 46 (37) ◽  
pp. 12636-12644 ◽  
Author(s):  
Corey A. Sanz ◽  
Zach R. McKay ◽  
Shaun W. C. MacLean ◽  
Brian O. Patrick ◽  
Robin G. Hicks
Keyword(s):  
Redox Reactions ◽  
Palladium Complexes ◽  
Redox Transformations

Bis(verdazyl)palladium complexes undergo a range of redox transformations, many of which involve ligand (hemi)lability.

Mechanism and Kinetics of Dark Iron Redox Transformations in Previously Photolyzed Acidic Natural Organic Matter Solutions

2013 ◽  
Vol 47 (4) ◽  
pp. 1861-1869 ◽  
Author(s):  
Shikha Garg ◽  
Hiroaki Ito ◽  
Andrew L. Rose ◽  
T. David Waite
Keyword(s):  
Organic Matter ◽  
Natural Organic Matter ◽  
Redox Transformations ◽  
Mechanism And Kinetics ◽  
Iron Redox ◽  
Kinetics Of

Electromicrobial regeneration of pyridine nucleotides and other preparative redox transformations with Clostridium thermoaceticum

1995 ◽  
Vol 42 (6) ◽  
pp. 916-922 ◽  
Author(s):  
M. Schulz ◽  
H. Leichmann ◽  
H. Günther ◽  
H. Simon
Keyword(s):  
Pyridine Nucleotides ◽  
Clostridium Thermoaceticum ◽  
Redox Transformations

Protective effects of hydrogen against irradiation

2021 ◽  
Vol 27 ◽  
Author(s):  
Yasuhiro Terasaki ◽  
Mika Terasaki ◽  
Akira Shimizu
Keyword(s):  
Oxidative Stress ◽  
Lung Injury ◽  
Cultured Cells ◽  
Animal Experiments ◽  
Lung Epithelial Cells ◽  
Lung Damage ◽  
Protective Effects ◽  
Chronic Radiation ◽  
Radiation Induced ◽  
Reactive Oxidants

: Radiation-induced lung injury is characterized by an acute pneumonia phase followed by a fibrotic phase. At the time of irradiation, a rapid, short-lived burst of reactive oxygen species (ROS) such as hydroxyl radicals (•OH) occurs, but chronic radiation-induced lung injury may occur due to excess ROS such as H2O2 , O2•− , ONOO− , and •OH. Molecular hydrogen (H2 ) is an efficient antioxidant that quickly diffuses cell membranes, reduces ROS such as •OH and ONOO− , and suppresses damage caused by oxidative stress in various organs. In 2011, through the evaluation of electron-spin resonance and fluorescent indicator signals, we had reported that H2 can eliminate •OH and can protect against oxidative stress-related apoptotic damage induced by irradiation of cultured lung epithelial cells. We had explored for the first time the radioprotective effects of H2 treatment on acute and chronic radiation-induced lung damage in mice by inhaled H2 gas (for acute) and imbibed H2 -enriched water (for chronic). Thus, we had proposed that H2 be considered a potential radioprotective agent. Recent publications have shown that H2 directly neutralizes highly reactive oxidants and indirectly reduces oxidative stress by regulating the expression of various genes. By regulating gene expression, H2 functions as an anti-inflammatory and anti-apoptotic molecule and promotes energy metabolism. The increased evidence obtained from cultured cells or animal experiments reveal a putative place for H2 treatment and its radioprotective effect clinically. This review focuses on major scientific advances of in the treatment of H2 as a new class of radioprotective agents.

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