Comparison of Solid-Phase Microextraction to Solvent Extraction and QuEChERS for Quantitative Analysis of Veterinary Drug Residues in Chicken and Beef Matrices

AbstractA rapid, simple, and sensitive method of detecting veterinary drug residues in animal food sources, including poultry and pork, was developed and validated. The method was optimized for over 155 veterinary drugs of 21 different classes. Sample pretreatment included a simple solid-liquid extraction step with 0.2% formic acid-acetonitrile-water and a purification step with a PRiME HLB (hydrophile-lipophile balance) solid-phase extraction cartridge. Data were collected using ultra-high-performance liquid chromatography coupled to Quadrupole-Exactive Orbitrap mass spectrometry. The limits of detection of 155 veterinary drugs ranged from 0.1 µg/kg to 10 µg/kg. The recovery rates were between 79.2 and 118.5 % in all matrices studied, with relative standard deviation values less than 15% (n = 6). The evaluated method allows the reliable screening, quantification, and identification of 155 veterinary drug residues in animal source food and has been successfully applied in authentic samples.

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Eco-friendly multivariate curve resolution-alternating least squares and chromatographic quantifications of some veterinary drug residues in pharmaceutical industrial wastewater

RSC Advances ◽

10.1039/d0ra08850a ◽

2021 ◽

Vol 11 (5) ◽

pp. 2935-2946

Author(s):

Osama I. Abdel Sattar ◽

Hamed H. M. Abuseada ◽

Mohamed S. Emara ◽

Mahmoud Rabee

Keyword(s):

Quantitative Analysis ◽

Analytical Methods ◽

Industrial Wastewater ◽

Cost Effective ◽

Multivariate Curve Resolution ◽

Veterinary Drug ◽

Veterinary Drug Residues ◽

Drug Residues ◽

Curve Resolution ◽

Wastewater Samples

Three eco-friendly and cost-effective analytical methods were developed and optimized for quantitative analysis of some veterinary drug residues in production wastewater samples.

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Simultaneous determination of multi-classes of veterinary drug residues in pork by ultra performance liquid chromatography coupled with quadrupole-time of flight mass spectrometry

Chinese Journal of Chromatography ◽

10.3724/sp.j.1123.2015.04033 ◽

2015 ◽

Vol 33 (9) ◽

pp. 1002 ◽

Cited By ~ 1

Author(s):

Wanyan ZHU ◽

Xin ZHANG ◽

Juan YANG ◽

Wenyuan XU ◽

Meiling XU

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Simultaneous Determination ◽

Time Of Flight ◽

Ultra Performance Liquid Chromatography ◽

Veterinary Drug ◽

Veterinary Drug Residues ◽

Drug Residues ◽

Flight Mass Spectrometry

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Evaluation of Certain Veterinary Drug Residues in Food. WHO Technical Report Series 855. VI and 59 pages, 10 tables. World Health Organization, Geneva 1995. Price: 12,- Sw.fr.

Nahrung/Food ◽

10.1002/food.19970410235 ◽

1997 ◽

Vol 41 (2) ◽

pp. 124-124

Author(s):

M. Kujawa

Keyword(s):

World Health Organization ◽

World Health ◽

Veterinary Drug ◽

Veterinary Drug Residues ◽

Drug Residues ◽

Technical Report Series ◽

Technical Report ◽

Health Organization

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Application of multiple headspace-solid-phase microextraction followed by gas chromatography–mass spectrometry to quantitative analysis of tomato aroma components

Journal of Chromatography A ◽

10.1016/j.chroma.2008.11.026 ◽

2009 ◽

Vol 1216 (1) ◽

pp. 127-133 ◽

Cited By ~ 49

Author(s):

E. Serrano ◽

J. Beltrán ◽

F. Hernández

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Quantitative Analysis ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Gas Chromatography Mass Spectrometry ◽

Headspace Solid Phase Microextraction ◽

Chromatography Mass Spectrometry ◽

Aroma Components

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Application of headspace solid phase microextraction to qualitative and quantitative analysis of tobacco additives in cigarettes

Journal of Chromatography A ◽

10.1016/j.chroma.2006.03.010 ◽

2006 ◽

Vol 1116 (1-2) ◽

pp. 10-19 ◽

Cited By ~ 25

Author(s):

Careen Merckel ◽

Fritz Pragst ◽

Astrid Ratzinger ◽

Beat Aebi ◽

Werner Bernhard ◽

...

Keyword(s):

Quantitative Analysis ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Qualitative And Quantitative Analysis ◽

Headspace Solid Phase Microextraction ◽

Qualitative And Quantitative

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Aromatic Constituents from Chinese Traditional Smoke-cured Bacon of Mini-pig

Food Science and Technology International ◽

10.1177/1082013208098331 ◽

2008 ◽

Vol 14 (4) ◽

pp. 329-340 ◽

Cited By ~ 20

Author(s):

J.-C. Xie ◽

B.-G. Sun ◽

S.-B. Wang

Keyword(s):

Solvent Extraction ◽

Phenolic Compounds ◽

Lipid Oxidation ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Active Regions ◽

Volatile Composition ◽

Headspace Solid Phase Microextraction ◽

Unsaturated Aldehydes

Volatile composition of Chinese traditional smoke-cured bacon of Mini-pig breed was first characterized. Both headspace solid phase microextraction (SPME) and simultaneous distillation and solvent extraction (SDE) were performed. SDE exhibited efficiency in the extraction of representative aromatic volatiles especially the phenolic smoky flavors from the bacon sample. In total, 104 different components were found with the major quantity and kinds of aromas being the volatile saturated and unsaturated aldehydes from lipid oxidation and the phenolic compounds from smoke. Olfactory evaluation (GC-O) of the SDE extract revealed five basic odor patterns pertaining to 53 odor active regions and 47 odorants. Some key flavors accounting for the bacon aroma were (E, E)-2, 4-decadienal, 3-(methylthio) propanal, 2-furanmethanol, guaiacol, 3-ethylphenol and 2, 5-dimethylpyrazine.

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