Simultaneous Imaging and Selective Photothermal Therapy through Aptamer-Driven Au Nanosphere Clustering

2018 ◽  
Vol 10 (2) ◽  
pp. 183-188 ◽  
Author(s):  
Zhenping Guan ◽  
Taishi Zhang ◽  
Hai Zhu ◽  
Da Lyu ◽  
Sreelatha Sarangapani ◽  
...  
2016 ◽  
Vol 52 (74) ◽  
pp. 11068-11071 ◽  
Author(s):  
Mingyu Gou ◽  
Shengnan Li ◽  
Lingyu Zhang ◽  
Lu Li ◽  
Chungang Wang ◽  
...  

We report herein a facile one-pot synthesis of carbon/calcium phosphate/Fe3O4 composite nanoparticles, which were employed as pH/NIR-responsive drug delivery vehicles for simultaneous MRI and chemo-photothermal therapy.


2016 ◽  
Vol 4 (35) ◽  
pp. 5809-5813 ◽  
Author(s):  
Chunyan Wang ◽  
Lingyu Zhang ◽  
Shengnan Li ◽  
Manjie Zhang ◽  
Tingting Wang ◽  
...  

A simple method is developed to synthesize Fe3O4@C/ZnP NPs for simultaneous MRI and synergic chemo-photothermal therapy.


2014 ◽  
Vol 2 (6) ◽  
pp. 915-923 ◽  
Author(s):  
Hui Wang ◽  
Jing Shen ◽  
Yingyu Li ◽  
Zengyan Wei ◽  
Guixin Cao ◽  
...  

The multifunctional hybrid nanoparticles described demonstrate great promise towards advanced nanoplatforms for simultaneous imaging diagnostics and high efficacy therapy.


2020 ◽  
Vol 26 (42) ◽  
pp. 5503-5517
Author(s):  
Shivani Rai Paliwal ◽  
Rameshroo Kenwat ◽  
Sabyasachi Maiti ◽  
Rishi Paliwal

Nanotheranostics, an approach of combining both diagnosis and therapy, is one of the latest advances in cancer therapy particularly. Nanocarriers designed and derived from inorganic materials such as like gold nanoparticles, silica nanoparticles, magnetic nanoparticles and carbon nanotubes have been explored for tremendous applications in this area. Similarly, nanoparticles composed of some organic material alone or in combination with inorganic nano-cargos have been developed pre-clinically and possess excellent features desired. Photothermal therapy, MRI, simultaneous imaging and delivery, and combination chemotherapy with a diagnosis are a few of the known methods exploring cancer therapy and detection at organ/tissue/molecular/sub-cellular level. This review comprises an overview of the recent reports meant for nano theranostics purposes. Targeted cancer nanotheranostics have been included for understating tumor micro-environment or cell-specific targeting approach employed. A brief account of various strategies is also included for the readers highlighting the mechanism of cancer therapy.


2020 ◽  
Author(s):  
zhihong sun ◽  
Guanjun Deng ◽  
Xinghua Peng ◽  
Xiuli Xu ◽  
Lanlan Liu ◽  
...  

Recently, photothermal-immuno synergistic therapy under mild temperature (~ 45 °C) has got broad interest in cancer treatment. Inhibition the intratumorally HSPs production is the key to accomplish highly efficient and mild photothermal therapy. In this work, we developed biomimetic nanoterminators with mature DCs functions by coating the mature dendritic cell membrane on photothermal nanoagents. As-prepared nanoterminators could automatically locate on T cell in the complex tumor-immune microenvironment and promote the T cells proliferation, activation and cytokine secretion, which could not only inhibit the expression of heat shock proteins to cooperate on highly efficient mild photothermal therapy (~42°C), but also promote tumor apoptosis during the treatment. More importantly, this nanoterminator could serve as vaccine to trigger anti-tumor immune response of the whole body, which would be promising to long-life tumor inhibition and termination.


ACS Nano ◽  
2016 ◽  
Vol 10 (9) ◽  
pp. 8578-8590 ◽  
Author(s):  
Shouju Wang ◽  
Ying Tian ◽  
Wei Tian ◽  
Jing Sun ◽  
Shuang Zhao ◽  
...  

ACS Nano ◽  
2016 ◽  
Vol 10 (2) ◽  
pp. 2375-2385 ◽  
Author(s):  
Yanlei Liu ◽  
Meng Yang ◽  
Jingpu Zhang ◽  
Xiao Zhi ◽  
Chao Li ◽  
...  

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...


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