Divalent Multilinking Bonds Control Growth and Morphology of Nanopolymers

Background: Radiation Therapy (RT) is an established treatment option for benign intracranial lesions. The aim of this study is to display an update on the role of RT concerning the most frequent benign brain lesions and tumors. Methods: Published articles about RT and meningiomas, Vestibular Schwannomas (VSs), Pituitary Adenomas (PAs), Arteriovenous Malformations (AVMs) and craniopharyngiomas were reviewed and extracted data were used. Results: In meningiomas RT is applied as an adjuvant therapy, in case of patientrefusing surgery or in unresectable tumors. The available techniques are External Beam RT (EBRT) and stereotactic ones such as Stereotactic Radiosurgery (SRS), Fractionated Stereotactic RT (FSRT), Intensity Modulated RT (IMRT) and proton-beam therapy. The same indications are considered in PAs, in which SRS and FSRT achieve excellent tumor control rate (92-100%), acceptable hormone remission rates (>50%) and decreased Adverse Radiation Effects (AREs). Upon tumor growth or neurological deterioration, RT emerges as alone or adjuvant treatment against VSs, with SRS, FSRT, EBRT or protonbeam therapy presenting excellent tumor control growth (>90%), facial nerve (84-100%), trigeminal nerve (74-99%) and hearing (>50%) preservation. SRS poses an effective treatment modality of certain AVMs, demonstrating a 3-year obliteration rate of 80%. Lastly, a combination of microsurgery and RT presents equal local control and 5-year survival rate (>90%) but improved toxicity profile compared to total resection in case of craniopharyngiomas. Conclusion: RT comprises an effective treatment modality of benign brain and intracranial lesions. By minimizing its AREs with optimal use, RT projects as a potent tool against such diseases.

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Toward Unity among Environmentalists

10.1093/oso/9780195093971.001.0001 ◽

1995 ◽

Author(s):

Bryan G. Norton

Keyword(s):

Resource Use ◽

Wide Spectrum ◽

Strong Support ◽

Environmental Issues ◽

Value Systems ◽

Special Interests ◽

Unified Approach ◽

Policy Makers ◽

The Past ◽

Control Growth

Today, six out of ten Americans describe themselves as "active" environmentalists or as "sympathetic" to the movement's concerns. The movement, in turn, reflects this millions-strong support in its diversity, encompassing a wide spectrum of causes, groups, and sometimes conflicting special interests. For far-sighted activists and policy makers, the question is how this diversity affects the ability to achieve key goals in the battle against pollution, erosion, and out-of-control growth. This insightful book offers an overview of the movement -- its past as well as its present -- and issues the most persuasive call yet for a unified approach to solving environmental problems. Focusing on examples from resource use, pollution control, protection of species and habitats, and land use, the author shows how the dynamics of diversity have actually hindered environmentalists in the past, but also how a convergence of these interests around forward-looking policies can be effected, despite variance in value systems espoused. The book is thus not only an assessment of today's movement, but a blueprint for action that can help pull together many different concerns under a common banner. Anyone interested in environmental issues and active approaches to their solution will find the author's observations both astute and creative.

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Kog1/Raptor mediates metabolic rewiring during nutrient limitation by controlling SNF1/AMPK activity

Science Advances ◽

10.1126/sciadv.abe5544 ◽

2021 ◽

Vol 7 (16) ◽

pp. eabe5544

Author(s):

Zeenat Rashida ◽

Rajalakshmi Srinivasan ◽

Meghana Cyanam ◽

Sunil Laxman

Keyword(s):

Amino Acid ◽

Nutrient Limitation ◽

Carbon Flux ◽

Metabolic Flux ◽

Carbon Allocation ◽

Carbon Utilization ◽

Acid Biosynthesis ◽

Control Growth ◽

Ampk Activity ◽

Delayed Growth

In changing environments, cells modulate resource budgeting through distinct metabolic routes to control growth. Accordingly, the TORC1 and SNF1/AMPK pathways operate contrastingly in nutrient replete or limited environments to maintain homeostasis. The functions of TORC1 under glucose and amino acid limitation are relatively unknown. We identified a modified form of the yeast TORC1 component Kog1/Raptor, which exhibits delayed growth exclusively during glucose and amino acid limitations. Using this, we found a necessary function for Kog1 in these conditions where TORC1 kinase activity is undetectable. Metabolic flux and transcriptome analysis revealed that Kog1 controls SNF1-dependent carbon flux apportioning between glutamate/amino acid biosynthesis and gluconeogenesis. Kog1 regulates SNF1/AMPK activity and outputs and mediates a rapamycin-independent activation of the SNF1 targets Mig1 and Cat8. This enables effective glucose derepression, gluconeogenesis activation, and carbon allocation through different pathways. Therefore, Kog1 centrally regulates metabolic homeostasis and carbon utilization during nutrient limitation by managing SNF1 activity.

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Environmental factors affect efficacy of some essential oils and resveratrol to control growth and ochratoxin A production by Penicillium verrucosum and Aspergillus westerdijkiae on wheat grain

Journal of Stored Products Research ◽

10.1016/j.jspr.2008.03.004 ◽

2008 ◽

Vol 44 (4) ◽

pp. 341-346 ◽

Cited By ~ 38

Author(s):

David Aldred ◽

Victoria Cairns-Fuller ◽

Naresh Magan

Keyword(s):

Environmental Factors ◽

Essential Oils ◽

Ochratoxin A ◽

Wheat Grain ◽

Penicillium Verrucosum ◽

Control Growth ◽

Aspergillus Westerdijkiae

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Influence of Application Method on the Activity of Butylate and EPTC in Reduced-Tillage Corn (Zea mays)

Weed Science ◽

10.1017/s0043174500053911 ◽

1987 ◽

Vol 35 (3) ◽

pp. 412-417 ◽

Cited By ~ 5

Author(s):

Douglas D. Buhler

Keyword(s):

Zea Mays ◽

Weed Control ◽

The Other ◽

Growth Chamber ◽

Reduced Tillage ◽

Corn Yield ◽

Liquid Fertilizer ◽

Application Method ◽

Control Growth ◽

Application Methods

Weed control in reduced-tillage corn (Zea maysL. ‘Pioneer 3732′) with butylate [S-ethyl bis(2-methylpropyl) carbamothioate] and EPTC (S-ethyl dipropyl carbarnothioate) was not reduced when these herbicides were applied jointly with dry or liquid fertilizer. In most cases, application with fertilizer resulted in weed control similar to that observed when the herbicide was applied in water at 285 L/ha. Butylate applied as a granular formulation also gave weed control similar to the spray at 285 L/ha. Application in 95 L/ha of water consistently resulted in reduced weed control. Corn injury was not greatly influenced by application method, and differences in corn yield appeared to be due to differences in weed control. Growth chamber bioassays indicated that both butylate and EPTC dissipated more rapidly when applied in 95 L/ha of water than the other application methods, which may explain differences in weed control observed in the field.

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FLURPRIMIDOL PREPLANT BULB SOAKS CONTROL GROWTH OF POTTED LILIUMS

Acta Horticulturae ◽

10.17660/actahortic.2011.900.8 ◽

2011 ◽

pp. 79-87

Author(s):

B.E. Whipker ◽

I. McCall ◽

J. Barnes ◽

W. Buhler ◽

B. Krug ◽

...

Keyword(s):

Control Growth

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14-3-3ɛ antagonizes FoxO to control growth, apoptosis and longevity inDrosophila

Aging Cell ◽

10.1111/j.1474-9726.2008.00420.x ◽

2008 ◽

Vol 7 (5) ◽

pp. 688-699 ◽

Cited By ~ 51

Author(s):

Mette Damgaard Nielsen ◽

Xi Luo ◽

Benoît Biteau ◽

Keith Syverson ◽

Heinrich Jasper

Keyword(s):

Control Growth

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SYNTHESIS AND ANTICANCER ACTIVITY EVALUATION OF SOME SCHIFF BASES OF 1, 3, 4-OXADIAZOLE

INDIAN DRUGS ◽

10.53879/id.56.03.11589 ◽

2019 ◽

Vol 56 (03) ◽

pp. 12-17

Author(s):

Manpreet Kaur ◽

S. Singh ◽

Keyword(s):

Schiff Base ◽

Growth Inhibition ◽

Anticancer Activity ◽

Maximum Growth ◽

Schiff Base Derivatives ◽

Control Growth ◽

Anti Cancer ◽

Oxadiazole Derivatives ◽

Cancer Activity ◽

Mcf 7

A new series of 2,5-disubstituted-1,3,4-oxadiazole derivatives has been synthesized with the help of different aromatic benzaldehydes and final compounds were characterized by FTIR and 1H NMR. 2,5- disubstituted-1,3,4-oxadiazole derivatives were synthesized by the reaction of Schiff base derivatives with 2,5-disubstituted-1,3,4-oxadiazoles. All the synthesized compounds were screened for their anticancer activity. These compounds were evaluated for their anticancer activity against various cancer cell lines. Five of the compounds possessed good to moderate anti-cancer activity. Three of the synthesized compounds i.e. 6a, 6f and 6g were found to possess maximum growth inhibition. The order for the % control growth inhibition of MCF-7 was found to be 6a>6f>6g>5b>6h, as shown in Table II-VI.

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