Systematic Evaluation of Transferrin-Modified Porous Silicon Nanoparticles for Targeted Delivery of Doxorubicin to Glioblastoma

2019 ◽  
Vol 11 (37) ◽  
pp. 33637-33649 ◽  
Author(s):  
Meihua Luo ◽  
Guido Lewik ◽  
Julian Charles Ratcliffe ◽  
Chung Hang Jonathan Choi ◽  
Ermei Mäkilä ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Targeted Delivery ◽  
Silicon Nanoparticles ◽  
Systematic Evaluation ◽  
Porous Silicon Nanoparticles

scholarly journals Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

2021 ◽  
Vol 9 (1) ◽  
pp. 133-147
Author(s):  
Terence Tieu ◽  
Marcin Wojnilowicz ◽  
Pie Huda ◽  
Kristofer J. Thurecht ◽  
Helmut Thissen ◽  
...  
Keyword(s):  
Side Effects ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Silicon Nanoparticles ◽  
High Drug ◽  
Drug Concentrations ◽  
Porous Silicon Nanoparticles

Targeted delivery of chemotherapeutics to cancer cells has the potential to yield high drug concentrations in cancer cells while minimizing any unwanted side effects.

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

scholarly journals Tracking the Fate of Porous Silicon Nanoparticles Delivering a Peptide Payload by Intrinsic Photoluminescence Lifetime

2018 ◽  
Vol 30 (35) ◽  
pp. 1802878 ◽  
Author(s):  
Yusung Jin ◽  
Dokyoung Kim ◽  
Hajung Roh ◽  
Sojeong Kim ◽  
Sazid Hussain ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Photoluminescence Lifetime

scholarly journals Ex vivo biodistribution of gallium-68-labeled porous silicon nanoparticles

2020 ◽  
Vol 1439 ◽  
pp. 012035
Author(s):  
V K Tishchenko ◽  
V. M. Petriev ◽  
A A Mikhailovskaya ◽  
O A Smoryzanova ◽  
A V Kabashin ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Ex Vivo ◽  
Porous Silicon Nanoparticles ◽  
Gallium 68 ◽  
Ex Vivo Biodistribution

scholarly journals Transferrin-targeted porous silicon nanoparticles reduce glioblastoma cell migration across tight extracellular space

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Sana Sheykhzadeh ◽  
Meihua Luo ◽  
Bo Peng ◽  
Jacinta White ◽  
Youssef Abdalla ◽  
...  
Keyword(s):  
Cell Migration ◽  
Porous Silicon ◽  
Extracellular Space ◽  
Silicon Nanoparticles ◽  
Glioblastoma Cell ◽  
Porous Silicon Nanoparticles
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