scholarly journals Nanobody-displaying porous silicon nanoparticles for the co-delivery of siRNA and doxorubicin

2021 ◽  
Vol 9 (1) ◽  
pp. 133-147
Author(s):  
Terence Tieu ◽  
Marcin Wojnilowicz ◽  
Pie Huda ◽  
Kristofer J. Thurecht ◽  
Helmut Thissen ◽  
...  
Keyword(s):  
Side Effects ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Targeted Delivery ◽  
Silicon Nanoparticles ◽  
High Drug ◽  
Drug Concentrations ◽  
Porous Silicon Nanoparticles

Targeted delivery of chemotherapeutics to cancer cells has the potential to yield high drug concentrations in cancer cells while minimizing any unwanted side effects.

High loading of doxorubicin into styrene-terminated porous silicon nanoparticles via π-stacking for cancer treatments in vitro

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44660-44665 ◽  
Author(s):  
Bing Xia ◽  
Bin Wang ◽  
Wenyi Zhang ◽  
Jisen Shi
Keyword(s):  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
High Loading ◽  
Cancer Treatments ◽  
Π Stacking ◽  
Porous Silicon Nanoparticles

Styrene-terminated PSiNPs were fabricated for high loading of doxorubicin via π-stacking, which exhibited an excellent capability for killing cancer cells.

Systematic Evaluation of Transferrin-Modified Porous Silicon Nanoparticles for Targeted Delivery of Doxorubicin to Glioblastoma

2019 ◽  
Vol 11 (37) ◽  
pp. 33637-33649 ◽  
Author(s):  
Meihua Luo ◽  
Guido Lewik ◽  
Julian Charles Ratcliffe ◽  
Chung Hang Jonathan Choi ◽  
Ermei Mäkilä ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Targeted Delivery ◽  
Silicon Nanoparticles ◽  
Systematic Evaluation ◽  
Porous Silicon Nanoparticles

scholarly journals Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

2016 ◽  
Vol 4 (21) ◽  
pp. 3639-3642 ◽  
Author(s):  
Arnaud Chaix ◽  
Khaled El Cheikh ◽  
Elise Bouffard ◽  
Marie Maynadier ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
Prostate Cancer Cells ◽  
Mesoporous Silicon ◽  
Two Photon ◽  
Porous Silicon Nanoparticles ◽  
Mannose 6 Phosphate

Porous silicon nanoparticles grafted with a mannose-6-phosphate analogue were designed for targeting prostate cancer cells.

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

2016 ◽  
Vol 6 (3) ◽  
pp. 1601009 ◽  
Author(s):  
Zehua Liu ◽  
Vimalkumar Balasubramanian ◽  
Chinmay Bhat ◽  
Mikko Vahermo ◽  
Ermei Mäkilä ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

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