Fos Expression in the Rat Brain After Intraperitoneal Injection of Staphylococcus Enterotoxin B and the Effect of Vagotomy

2004 ◽  
Vol 29 (9) ◽  
pp. 1667-1674 ◽  
Author(s):  
Xi Wang ◽  
Bai-Ren Wang ◽  
Xi-Jing Zhang ◽  
Xiao-Li Duan ◽  
Xiang Guo ◽  
...  
Keyword(s):  
Rat Brain ◽  
Intraperitoneal Injection ◽  
Enterotoxin B ◽  
Fos Expression ◽  
Staphylococcus Enterotoxin B

Staphylococcal enterotoxin B induces fever, brain c-Fos expression, and serum corticosterone in rats

2001 ◽  
Vol 280 (5) ◽  
pp. R1434-R1439 ◽  
Author(s):  
Lisa E. Goehler ◽  
Ron P. A. Gaykema ◽  
Michael K. Hansen ◽  
Jayme L. Kleiner ◽  
Steven F. Maier ◽  
...  
Keyword(s):  
T Cell ◽  
Host Defense ◽  
Intraperitoneal Injection ◽  
Defense Responses ◽  
Plasma Corticosterone ◽  
Significant Rise ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B ◽  
Fos Expression

The paraventricular nucleus of the hypothalamus (PVH) occupies a pivotal point within the network of brain nuclei coordinating critical host-defense responses. In mice, T cell-dependent immune stimuli, including the bacterial superantigen staphylococcal enterotoxin B (SEB), can activate the PVH. To determine whether T cell-dependent immune stimuli activate the PVH in rats, we assessed plasma corticosterone (Cort) levels, fever responses, and c-Fos expression in the PVH in animals treated with intraperitoneal injections of SEB. In animals with previously implanted abdominal thermisters, intraperitoneal injection of 1 mg/kg SEB resulted in a significant rise in body temperature, with a latency of 3.5–4 h. In separate animals, intraperitoneal injection of 1 mg/kg SEB resulted in a significant elevation of plasma Cort and induced c-Fos expression in parvocellular neurons within the PVH. These results support the idea that T cell-dependent immune stimuli activate brain pathways mediating host-defense responses such as fever and neuroendocrine changes.

C-fos expression in the rat brain after intraperitoneal injection of lithium chloride

Neuroreport ◽  
1992 ◽  
Vol 3 (12) ◽  
pp. 1049-1052 ◽  
Author(s):  
T. Yamamoto ◽  
T. Shimura ◽  
N. Sako ◽  
S. Azuma ◽  
W. -Zh. Bai ◽  
...  
Keyword(s):  
Rat Brain ◽  
Lithium Chloride ◽  
Intraperitoneal Injection ◽  
Fos Expression

Specific Detection of Staphylococcus Enterotoxin B in Milk Using Piezoresistive Cantilever Aptasensor

2015 ◽  
Vol 645-646 ◽  
pp. 1298-1302
Author(s):  
Rui Zhao ◽  
Yong Zheng Wen ◽  
Wei Ma ◽  
Jian Cheng Yang ◽  
Xiao Mei Yu
Keyword(s):  
High Sensitivity ◽  
Rapid Response ◽  
Experimental Results ◽  
Quick Response ◽  
Specific Detection ◽  
Detection Range ◽  
Coated Surface ◽  
Enterotoxin B ◽  
Food Commodities ◽  
Staphylococcus Enterotoxin B

In this paper, an aptasensor with high sensitivity and rapid response was developed for the detection of staphylococcus enterotoxin B (SEB) by using thiol-modified piezoresistive cantilever. Thiol-modified aptamers, acting as the functionalized sensing elements, were immobilized on the nanogold-coated surface of the sensing cantilever as agents for detecting SEB. By using the functionalized aptasensors, different concentrations of SEB were detected with a wide detection range of 6-100 ng/mL and a quick response in milk. The experimental results indicated that the cantilever-based aptasensors had sufficient sensitivity for the detection of SEB in real food commodities and might provide an economical platform for on-site detections of different toxicants with the advantages of portability, high sensitivity, and rapid response.

Differential stimulation of c-fos expression in hypothalamic nuclei of the rat brain during short-term heat acclimation and mild dehydration

1998 ◽  
Vol 798 (1-2) ◽  
pp. 127-139 ◽  
Author(s):  
Panagiotis Patronas ◽  
Michal Horowitz ◽  
Eckhart Simon ◽  
Rüdiger Gerstberger
Keyword(s):  
Rat Brain ◽  
Heat Acclimation ◽  
Short Term ◽  
Hypothalamic Nuclei ◽  
Fos Expression ◽  
Stimulation Of

Habituation to repeated restraint stress is associated with lack of stress-induced c-fos expression in primary sensory processing areas of the rat brain

Neuroscience ◽  
2006 ◽  
Vol 138 (4) ◽  
pp. 1067-1081 ◽  
Author(s):  
M. Girotti ◽  
T.W.W. Pace ◽  
R.I. Gaylord ◽  
B.A. Rubin ◽  
J.P. Herman ◽  
...  
Keyword(s):  
Rat Brain ◽  
Sensory Processing ◽  
Restraint Stress ◽  
Repeated Restraint Stress ◽  
Fos Expression
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