Effect of Dietary DHA on DHA Levels in Retinal Rod Outer Segments in Young versus Mature Rats

2003 ◽  
Vol 73 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Nishizawa ◽  
Wang ◽  
Sekine ◽  
Saito
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Total Energy ◽  
Acid Composition ◽  
Diet Group ◽  
Retinal Rod ◽  
Old Rats ◽  
High Doses ◽  
One Year ◽  
Retinal Rod Outer Segments

We compared the effect of direct supplementation with docosahexaenoic acid (DHA) on the fatty acid composition of the liver and the rod outer segment (ROS) membranes of the retina in young (five-week-old) and mature (one-year-old) rats. In young rats, a high content of DHA in the diet (9.7% of total energy) effectively increased the proportion of DHA in ROS membranes (41.8%), compared with the proportion observed in a linoleic acid (LA) diet group (control, 31.6%). The proportion of DHA was also significantly higher in the livers of young DHA-fed rats. These results show that direct supplementation with DHA is very effective in increasing DHA levels in the ROS membranes and livers of developing animals. In contrast, in mature rats there was no significant increase in the proportion of DHA in the ROS membranes, even after the highest dose (8.4% of total energy) of DHA, although the proportion of DHA was significantly higher in the livers of DHA-fed rats. The changes in fatty acid composition in the ROS membranes were different in young and mature rats fed high-DHA diets. Our findings indicate that mature rats maintain a constant level of DHA in the ROS membranes even after being directly supplemented with high doses of DHA.

Morphology and fatty acid composition of erythrocytes from monkeys exposed to ozone for one year

1983 ◽  
Vol 32 (3) ◽  
pp. 445-454 ◽  
Author(s):  
Edward C. Larkin ◽  
Steven C. Goheen ◽  
G.Ananda Rao
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
One Year

scholarly journals Fatty Acid Composition of Phospholipids and in the Central and External Positions of Triacylglycerol in Muscle and Subcutaneous Fat of Beef Steers Fed Diets Supplemented with Oil Containing n6 and n3 Fatty Acids While Undergoing One of Three 48 h Feed Withdrawal Treatments

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
C. Margetak ◽  
G. Travis ◽  
T. Entz ◽  
P. S. Mir ◽  
S. Wei ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Control Diet ◽  
Subcutaneous Fat ◽  
Beef Steers ◽  
Feed Withdrawal ◽  
One Year ◽  
Dietary Oil

This study was designed to determine the effects of dietary oil and feed withdrawal treatments on fatty acid composition of phospholipids of triacylglycerol in pars costalis diaphragmatis muscle and subcutaneous fat from the brisket. A 2 × 3 factorial experiment was conducted with crossbred steers with an initial body weight of 280.5 ± 5.8 kg. Steers were fed either a control or an oil containing diet where 5% of the control diet was replaced with an equal mixture sunflower and flax oil while undergoing one of three feed withdrawal treatments: no withdrawal, a single 48 h withdrawal before initiation of fattening at one year of age, or 48 h withdrawal at 8 wk intervals from weaning to initiation of fattening. At time of processing samples of muscle and fat were obtained and analyzed to determine fatty acid composition. Disproportionate distribution of the fatty acids was observed by diet, feed withdrawal regimen and whether the sample was from muscle or fat. Differences are discussed in detail, and our data suggests a special function for the fatty acids that accumulate in specific positions of the triacylglycerol due to treatment.

scholarly journals Modelling the predictable effects of dietary lipid sources on the fillet fatty acid composition of one-year-old gilthead sea bream (Sparus aurata L.)

2011 ◽  
Vol 124 (2) ◽  
pp. 538-544 ◽  
Author(s):  
Laura Benedito-Palos ◽  
Azucena Bermejo-Nogales ◽  
Alexandros I. Karampatos ◽  
Gabriel F. Ballester-Lozano ◽  
Juan C. Navarro ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Sparus Aurata ◽  
Dietary Lipid ◽  
Gilthead Sea Bream ◽  
Sea Bream ◽  
One Year

scholarly journals High Fat Diet Rich in Linoleic Acid Oil Increases Linoleate-Rich Cardiolipin Species in C57BL6/J Mice

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 1229-1229
Author(s):  
Connor Mahler ◽  
Austin Angelotti ◽  
Rachel Cole ◽  
Deena Snoke ◽  
Genevieve Sparagna ◽  
...  
Keyword(s):  
Body Weight ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Linoleic Acid ◽  
Blood Glucose ◽  
Acid Composition ◽  
Dietary Fat ◽  
High Fat Diet ◽  
Diet Group ◽  
High Fat

Abstract Objectives Dietary fat quality alters the fatty acid composition of phospholipids in cell membranes. The fatty acid composition of the inner mitochondrial membrane phospholipid cardiolipin (CL) impacts mitochondria function where linoleic acid (LA) -rich cardiolipin, e.g., tetralinoleoyl-cardiolipin (L4CL). This study compared the effects of a LA-rich diet and a saturated fat (SF)-rich diet on L4CL in the liver of mice. Methods Male C57BL6/J mice (9 weeks, N = 24) randomized by body weight to a high fat diet (24% fat w/w) containing LA-rich safflower oil (SO) or SF-rich oil (LD) for 18 weeks. Food intake and body weight were measured every two days. Fasting blood glucose and body composition (Echo/MRI) were measured in the washout period and again 11 weeks later. Insulin tolerance test (ITT) measured insulin sensitivity on day 85, and mice were euthanized starting after day 100. Liver cardiolipin speciation was measured using HPLC/MS. A two-sample t-test at a 5% significance level was used to determine differences between diet groups. Results Body weight, cumulative food intake, adipose and lean tissues were not significantly different between diet groups at Day 130. Fasting glucose between diets was not significantly different at any timepoints throughout the study. Blood glucose during the ITT was significantly different between LA-rich and SF-rich diets for the last two time points, 90 minute and 120 minute. The SO diet increased hepatic L4CL (% of total CL) compared to the LD diet (P-value: < 0.01). Conclusions Hepatic CL fatty acid composition reflected dietary fat composition. Feeding of a high fat LA-rich diet increased hepatic L4CL species and hastened resolution of glucose levels in response to insulin in the SO diet group (vs. LD diet group). Funding Sources Supported by Human Nutrition - Human Sciences, Carol S. Kennedy endowment, OADRC.

Effect of Maternal Essential Fatty Acid Supply on Fatty Acid Composition of Brain, Liver, Muscle and Serum in 21-day-old Rats

1972 ◽  
Vol 102 (6) ◽  
pp. 773-782 ◽  
Author(s):  
C. Alling ◽  
A. Bruce ◽  
I. Karlsson ◽  
O. Sapia ◽  
L. Svennerholm
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Acid Composition ◽  
Old Rats

Platelet Aggregation in Finnish Men and Its Relation to Fatty Acids in Platelets, Plasma and Adipose Tissue

1985 ◽  
Vol 54 (03) ◽  
pp. 563-569 ◽  
Author(s):  
M K Salo ◽  
E Vartiainen ◽  
P Puska ◽  
T Nikkari
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Platelet Aggregation ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Free Living ◽  
Ω3 Fatty Acids ◽  
Induced Aggregation

SummaryPlatelet aggregation and its relation to fatty acid composition of platelets, plasma and adipose tissue was determined in 196 randomly selected, free-living, 40-49-year-old men in two regions of Finland (east and southwest) with a nearly twofold difference in the IHD rate.There were no significant east-southwest differences in platelet aggregation induced with ADP, thrombin or epinephrine. ADP-induced platelet secondary aggregation showed significant negative associations with all C20-C22 ω3-fatty acids in platelets (r = -0.26 - -0.40) and with the platelet 20: 5ω3/20: 4ω 6 and ω3/ ω6 ratios, but significant positive correlations with the contents of 18:2 in adipose tissue (r = 0.20) and plasma triglycerides (TG) (r = 0.29). Epinephrine-induced aggregation correlated negatively with 20: 5ω 3 in plasma cholesteryl esters (CE) (r = -0.23) and TG (r = -0.29), and positively with the total percentage of saturated fatty acids in platelets (r = 0.33), but had no significant correlations with any of the ω6-fatty acids. Thrombin-induced aggregation correlated negatively with the ω3/6ω ratio in adipose tissue (r = -0.25) and the 20: 3ω6/20: 4ω 6 ratio in plasma CE (r = -0.27) and free fatty acids (FFA) (r = -0.23), and positively with adipose tissue 18:2 (r = 0.23) and 20:4ω6 (r = 0.22) in plasma phospholipids (PL).The percentages of prostanoid precursors in platelet lipids, i. e. 20: 3ω 6, 20: 4ω 6 and 20 :5ω 3, correlated best with the same fatty acids in plasma CE (r = 0.32 - 0.77) and PL (r = 0.28 - 0.74). Platelet 20: 5ω 3 had highly significant negative correlations with the percentage of 18:2 in adipose tissue and all plasma lipid fractions (r = -0.35 - -0.44).These results suggest that, among a free-living population, relatively small changes in the fatty acid composition of plasma and platelets may be reflected in significant differences in platelet aggregation, and that an increase in linoleate-rich vegetable fat in the diet may not affect platelet function favourably unless it is accompanied by an adequate supply of ω3 fatty acids.

Health Benefits of Pumpkin Seed and Nutrition Profile of 35 Pumpkin Accessions

EDIS ◽  
2017 ◽  
Vol 2017 (6) ◽  
Author(s):  
Geoffrey M. Meru ◽  
Yuqing Fu ◽  
Dayana Leyva ◽  
Paul Sarnoski ◽  
Yavuz Yagiz
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Health Benefits ◽  
Pumpkin Seed ◽  
Production Practices

This article aims to summise production and nutrition aspects of pumpkin seed. Specifically, it focuses on health benefits of the seeds, production practices and provides data on the oil, protein and fatty acid composition of 35 pumpkin accessions.  

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