scholarly journals Visual Acuity, Erythrocyte Fatty Acid Composition, and Growth in Term Infants Fed Formulas with Long Chain Polyunsaturated Fatty Acids for One Year

1997 ◽  
Vol 41 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Nancy Auestad ◽  
Michael B Montalto ◽  
Robert T Hall ◽  
Kathleen M Fitzgerald ◽  
Robin E Wheller ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Visual Acuity ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Term Infants ◽  
Erythrocyte Fatty Acid ◽  
One Year ◽  
Long Chain

scholarly journals Polyunsaturated fatty acid concentrations in human hindmilk are stable throughout 12-months of lactation and provide a sustained intake to the infant during exclusive breastfeeding: an Italian study

2000 ◽  
Vol 84 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Franca Marangoni ◽  
Carlo Agostoni ◽  
Anna M. Lammard ◽  
Marcello Giovannini ◽  
Claudio Galli ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Human Milk ◽  
Acid Composition ◽  
Saturated Fatty Acids ◽  
Total Fat ◽  
Extended Lactation ◽  
Long Chain

While a wealth of data on the fatty acid composition of mature human milk has been published, limited information is available on the quantities of individual fatty acids supplied to the suckling infant with maternal milk, through the whole first year of life. Our aim was to qualitatively and quantitatively evaluate the fatty acid composition of human milk from Italian mothers, throughout extended lactation with particular emphasis on the long-chain polyunsaturated fatty acids. We have thus measured the total fat content and the concentrations of major fatty acids by quantitative GLC in pooled breast hindmilk collected from all feedings over 24 h at colostrum, 1, 3, 6, 9 and 12 months in ten mothers recruited after delivery of full-term infants. Total saturated fatty acids progressively increase and total monounsaturated progressively decrease as percentage levels, while among long-chain polyunsaturated fatty acids, percentages of arachidonic acid and docosahexaenoic acid decrease from colostrum up to the third month. Hindmilk total lipids (mg/dl) rise more than twofold up to 3 months, and then remain stable. The amounts (mg/dl) of linoleic acid and α-linolenic acid progressively increase, following the trend of total fat, while arachidonic and docosahexaenoic concentrations (mg/dl) remain stable throughout the whole nursing period. Assessment of the intakes per kg body weight shows different trends for the individual major long-chain polyunsaturated fatty acids supplied to the infant from hindmilk during exclusive breast-feeding (3 months). This information may be useful for the evaluation of infant intakes during extended lactation.

scholarly journals Omega-3 polyunsaturated fatty acids increase purine but not pyrimidine transport in L1210 leukaemia cells

1996 ◽  
Vol 315 (1) ◽  
pp. 329-333 ◽  
Author(s):  
Danielle MARTIN ◽  
Kelly A. MECKLING-GILL
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Fold Increase ◽  
Omega 3 ◽  
Membrane Phospholipids ◽  
Epa And Dha ◽  
Long Chain

Here we show that in vitro supplementation of L1210 murine lymphoblastic leukaemia cells with n-3 polyunsaturated fatty acids results in considerable changes in the fatty acid composition of membrane phospholipids. Incubations for 48 h with 30 μM eicosapentaenoic acid (20:5, n-3; EPA) or docosahexaenoic acid (22:6, n-3; DHA) results primarily in substitution of long-chain n-6 fatty acids with long-chain n-3 fatty acids. This results in a decrease in the n-6/n-3 ratio from 6.9 in unsupplemented cultures to 1.2 or 1.6 for EPA and DHA supplemented cultures, respectively. Coincident with these changes in membrane fatty acid composition, we observed a 5-fold increase in the rate of adenosine (5 μM) uptake via the nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter in EPA- and DHA- supplemented L1210 cells, relative to unsupplemented cells. This seemed to result from a decrease in the Km for adenosine from 12.5 μM in unsupplemented cultures to 5.1 μM in DHA-treated cultures. Guanosine (50 μM) transport was similarly affected by DHA with a 3.5-fold increase in the initial rate of uptake. In contrast, pyrimidine transport, as measured by uptake of thymidine and cytidine, was not similarly affected, suggesting that substrate recognition had been altered by fatty acid supplementation. Studies using [3H]NBMPR showed that there was no effect of EPA or DHA on either the number of NBMPR-binding sites or the affinity of these sites for NBMPR. This observation suggests that the increases in adenosine and guanosine transport were not due to increases in the number of transporter sites but rather that EPA and DHA directly or indirectly modulate transporter function.

scholarly journals Change in Fatty Acid Composition of Serum Lipids in Obese Females after Short-Term Weight Reducing Regimen with the Addition of n-3 Long Chain Polyunsaturated Fatty Acids In Comparison To Controls

2008 ◽  
pp. S57-S65 ◽  
Author(s):  
P Hlavatý ◽  
M Kunešová ◽  
M Gojová ◽  
E Tvrzická ◽  
M Vecka ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Acid Composition ◽  
Serum Lipids ◽  
Low Doses ◽  
Short Term ◽  
Significant Difference ◽  
Long Chain

Short-term weight-reducing regimens were shown to influence fatty acid composition of serum lipids unfavorably. Adding long chain n-3 polyunsaturated fatty acids (n-3 LC PUFA) to a low-calorie diet (LCD) could avoid these changes. The aim of this study was to examine the effect of a short-term in-patient weight-reducing regimen including LCD with yogurt enriched by low doses of n-3 PUFA (n-3 LCD). The enriched yogurt contained 790 mg of fish oil, predominantly eicosapentaenoic (20:5n-3; EPA) and docosahexaenoic (22:6n-3; DHA). Forty obese women were randomly assigned to the group consuming LCD and joghurt either with or without n-3 enrichment. Following the 3-week diet in the n-3 LCD group a significantly higher increase in the proportion of n-3 LC PUFA (sum of n-3 FA, EPA and DHA) in serum lipids was confirmed. In phospholipids (PL) a significant difference in the sum of n-6 fatty acids was found, a decrease in the n-3 LCD group and an increase in LCD group. Significantly higher increase in the PL palmitate (16:0) was shown in the LCD group. The results suggest that low doses of n-3 fatty acid enrichment can help to avoid unfavorable changes in fatty acid composition in serum lipids after a short-term weight-reducing regimen.

scholarly journals Fatty acid composition of breast meat in two lines of slow-growing chickens reared conventionally or on pasture

2018 ◽  
Vol 1 (1) ◽  
pp. 70 ◽  
Author(s):  
Teodora Popova ◽  
Evgeni Petkov ◽  
Maya Ignatova
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Lipid Profile ◽  
Acid Composition ◽  
Monounsaturated Fatty Acids ◽  
Breast Meat ◽  
Slow Growing ◽  
Long Chain

The study was carried out to compare the fatty acid composition of the breast meat in two lines of slow growing chickens - La Belle (LB) and Bresse (BB), reared conventionally or having access to pasture. The differences in the lipid profile due to the lines and rearing strategies were assessed through two-way ANOVA. Both factors influenced the lipid composition in the breast meat, however the effect of pasture was more pronounced. It was associated with lower contents of C14:0, C16:0 and C16:1Δ7 (P<0.001), C18:1 (P<0.05), total saturated (SFA) and monounsaturated fatty acids (MUFA) (P<0.01), and significant increase (P<0.001) of the long chain polyunsaturated fatty acids (PUFA). These changes in the lipid profile of the breast meat in the chickens reared outdoors led to considerably lower atherogenic and thrombogenic indices, reduced n-6/n-3 ratio (P<0.001), as well as higher P/S and h/H values (P<0.001). Differences in the fatty acid composition of the breast meat were also due to the line of the birds, showing advantage of the LB over BB chickens. The former had lower contents of saturated (P<0.001) but higher long chain polyunsaturated fatty acids (P<0.05) which determined better nutritional indices of the breast meat in the LB line.

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