Kognitive Defizite bei Schizophren Erkrankten

2015 ◽  
Vol 44 (2) ◽  
pp. 106-120 ◽  
Author(s):  
Almut Carolus ◽  
Petia Popova ◽  
Brigitte Rockstroh
Keyword(s):  
Test Battery ◽  
Cognitive Test ◽  
Kognitive Defizite ◽  
Kognitive Funktionen

Zusammenfassung. Theoretischer Hintergrund: Kognitive Funktionseinschränkungen sind zentrales Merkmal schizophrener Erkrankungen und werden entsprechend im Behandlungskonzept berücksichtigt. Kognitive Remediationsprogramme gelten als wirksam, Effektstärken als moderat. Trainingsvarianten werden zur Effektoptimierung erprobt. Fragestellung: Ist gezieltes Funktionstraining in neuroplastizitäts-orientiertem Lernkontext effektiver als breitgefächertes Behandlungsprogramm und werden Effekte durch das Erkrankungsstadium moduliert? Methode: Bei 59 chronisch und 31 ersthospitalisierten schizophren Erkrankten wurden kognitive Defizite über Testleistungen der MATRICS Consensus Cognitive Test Battery gegenüber 25 gesunder Kontrollpersonen erfasst. Testleistungen vor, nach 4-wöchiger Interventionsphase mit zwei spezifischen Trainings oder Standardbehandlung und 3-monatiger Katamnese prüften den Einfluss von Interventionstypus und Erkrankungsstadium auf Leistungsverbesserung. Ergebnisse: Sowohl chronische wie erstmals behandelte Patienten aller Behandlungsgruppen verbesserten sich signifikant über die Messzeitpunkte, obwohl Defizite relativ zu Kontrollen fortbestanden. Schlussfolgerungen: Spezifisches Training verbessert kognitive Funktionen nicht über Zeit/Remissionseffekte hinaus.

scholarly journals Concussion History and Cognitive Function in a Large Cohort of Adolescent Athletes

2018 ◽  
Vol 46 (13) ◽  
pp. 3262-3270 ◽  
Author(s):  
Kathryn M. Taylor ◽  
Marianthi-Anna Kioumourtzoglou ◽  
Jim Clover ◽  
Brent A. Coull ◽  
Jack T. Dennerlein ◽  
...  
Keyword(s):  
High School ◽  
Cognitive Function ◽  
Verbal Memory ◽  
Impulse Control ◽  
Visual Memory ◽  
Test Battery ◽  
Cognitive Test ◽  
Effect Estimate ◽  
Cognitive Score ◽  
And Performance

Background: The incidence of reported concussions in the adolescent population is increasing, yet research on the effects of concussions in this population is minimal and inconclusive. Purpose: To assess the association between concussion and performance on a cognitive test battery. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Using multivariate models, the authors assessed the association between concussion and performance on a cognitive test battery among 5616 high school and junior high school athletes. The researchers utilized a global cognitive score and scores for 5 domains: verbal memory, visual memory, visual motor, reaction time, and impulse control. Each cognitive score was converted to a z score with the mean and SD of the nonconcussed population. Results from each model were then interpreted as change in the standardized unit score. In the models, concussion was evaluated as ever having a concussion, number of concussions, time since last concussion, and age at first concussion. Results: Ever having a concussion was associated with a mean decrease of 0.11 standardized units (95% CI, −0.20 to −0.01) on the global cognitive score and lower scores in all cognitive domains. Each additional concussion was associated with lower scores on global cognitive function (effect estimate, −0.06; 95% CI, −0.11 to −0.02), verbal memory, visual memory, and impulse control. Concussion in early childhood was associated with lower global cognition (effect estimate, −0.05; 95% CI, −0.08 to −0.01), visual memory, and motor visual scores as compared with concussions in later childhood. The associations between time since last concussion and cognitive test scores were nonlinear, and on all tests, lower scores were observed even ≥1 year after the concussion. Conclusion: On the basis of objective performance metrics for cognitive function, concussions had a more persistent effect on cognitive function than previously thought. The age at which an individual has his or her first concussion may be an important factor in determining long-lasting cognitive effects.

Arizona Cognitive Test Battery

2010 ◽  
Author(s):  
Jamie O. Edgin ◽  
Gina M. Mason ◽  
Melissa J. Allman ◽  
George T. Capone ◽  
Iser DeLeon ◽  
...  
Keyword(s):  
Test Battery ◽  
Cognitive Test

scholarly journals Test Accuracy of the Montreal Cognitive Assessment in Screening for Early Poststroke Neurocognitive Disorder

Stroke ◽  
2021 ◽  
Vol 52 (1) ◽  
pp. 317-320
Author(s):  
Ragnhild Munthe-Kaas ◽  
Stina Aam ◽  
Ingvild Saltvedt ◽  
Torgeir Bruun Wyller ◽  
Sarah T. Pendlebury ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Cognitive Assessment ◽  
Test Battery ◽  
Montreal Cognitive Assessment ◽  
Cognitive Domain ◽  
Cognitive Test ◽  
Test Accuracy ◽  
Neurocognitive Disorder ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual

Background and Purpose: We determined the diagnostic accuracy of the Montreal Cognitive Assessment (MoCA) for poststroke neurocognitive disorder defined according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria in a prospective observational study. Methods: Consecutive participants able to complete a cognitive test battery and MoCA 3 months poststroke were included. The reference standard of neurocognitive disorder was defined as a score of ≥1.5 SD below the normative mean in ≥1 cognitive domain on the cognitive test battery. Results: Among 521 participants (43.6% women; mean age/SD, 71.5/12.0 years; mean education/SD, 12.4/3.8 years), the area under the receiver operating characteristic curve of MoCA for neurocognitive disorder was 0.80 (95% CI, 0.76–0.84). Using the standard MoCA cutoff <26, sensitivity was 0.71 (0.69–0.79) with specificity of 0.73 (0.66–0.76). MoCA cutoff of <27 gave higher sensitivity (0.82 [0.77–0.85]) at the expense of specificity (0.60 [0.53–0.66]). Discussion: MoCA has reasonable accuracy for poststroke neurocognitive disorder diagnosed using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria. Registration: URL: https://www.clinicaltrials.gov . Unique identifier: NCT02650531.

scholarly journals Evidence of Validity for a Newly Developed Digital Cognitive Test Battery

2020 ◽  
Vol 11 ◽  
Author(s):  
Stefan Vermeent ◽  
Ron Dotsch ◽  
Ben Schmand ◽  
Laura Klaming ◽  
Justin B. Miller ◽  
...  
Keyword(s):  
Test Battery ◽  
Cognitive Test

P1-517: VALIDITY AND RELIABILITY OF THE 10/66 DEMENTIA RESEARCH GROUP COGNITIVE TEST BATTERY FOR EARLY IDENTIFICATION OF COGNITIVE DECLINE IN MEXICO

2006 ◽  
Vol 14 (7S_Part_9) ◽  
pp. P529-P529
Author(s):  
Berenice Dafne Ortiz-Saavedra ◽  
Fernando Austria-Corrales ◽  
Claudia I. Astudillo-Garcia ◽  
Gilberto Isaac Acosta-Castillo ◽  
Ana Luisa Sosa-Ortiz
Keyword(s):  
Cognitive Decline ◽  
Research Group ◽  
Early Identification ◽  
Test Battery ◽  
Cognitive Test ◽  
Validity And Reliability ◽  
Dementia Research

[P1-326]: DETECTING COGNITIVE DISORDERS USING MUISTIKKO WEB-BASED COGNITIVE TEST BATTERY: VALIDATION IN THREE COHORTS

2017 ◽  
Vol 13 (7S_Part_7) ◽  
pp. P380-P380
Author(s):  
Teemu Paajanen ◽  
Shadi Mahdiani ◽  
Marie Bruun ◽  
Marta Baroni ◽  
Hanneke FM. Rhodius- Meester ◽  
...  
Keyword(s):  
Cognitive Disorders ◽  
Test Battery ◽  
Cognitive Test ◽  
Web Based

The effects of acute dopamine reuptake inhibition on cognitive function during passive hyperthermia

2020 ◽  
Author(s):  
Phillip J. Wallace ◽  
Ricardo S Martins ◽  
Jake S Scott ◽  
Scott W Steele ◽  
Matthew Greenway ◽  
...  
Keyword(s):  
Heat Stress ◽  
Executive Function ◽  
Cognitive Function ◽  
Thermal Strain ◽  
Maze Learning ◽  
Test Battery ◽  
Cognitive Test ◽  
Set Shifting ◽  
Heart Rates ◽  
The Impact

Dopamine activity can modulate physical performance in the heat, but less is known about its effects on cognition during thermal stress. Twelves males completed a randomized, double-blinded protocol consisting of oral ingestion of 20 mg of methylphenidate (MPH) or placebo (lactose pill) during passive heating using a water-perfused suit (water temperature ~49°C). To identify the impact of peripheral versus central thermal strain, a cognitive test battery was completed at four different thermal states: baseline (BASE; 37.2±0.6˚C core, 32.9±0.7˚C skin), neutral core-hot skin (NC-HS; 37.2±0.3˚C, 37.4±0.3˚C), hyperthermic core-hot skin (HC-HS; 38.7±0.4˚C, 38.7±0.2˚C), and hyperthermic core-cooled skin (HC-CS; 38.5±0.4˚C, 35.1±0.8˚C). The cognitive test battery consisted of the 2-back task (i.e. working memory), set-shifting (i.e. executive function), Groton Maze Learning Task (i.e. executive function) and detection task (i.e. psychomotor processing). MPH led to significantly higher heart rates (~5-15 b·min-1) at BASE, NC-HS, and HC-HS (all p<0.05). There were no significant differences in the number of errors made on each task (all p<0.05). Participants were significantly faster (p<0.05) on the set-shifting task in the HC-HS timepoint, irrespective of drug condition (p>0.05). In summary, we demonstrated that 20 mg of MPH did not significantly alter cognitive function during either normothermia or moderate hyperthermia. Novelty: ● 20 mg of MPH did not significantly alter cognitive function during passive heat stress ● MPH led to significant higher heart rates (~5-15 bmin-1) in thermoneutral and during passive heat stress ● Future studies are needed to determine the mechanisms of why MPH improves physical but not cognitive performance during heat stress

scholarly journals Age and education effects and norms on a cognitive test battery from a population-based cohort: The Monongahela–Youghiogheny Healthy Aging Team

2010 ◽  
Vol 14 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Mary Ganguli ◽  
Beth E. Snitz ◽  
Ching-Wen Lee ◽  
Joni Vanderbilt ◽  
Judith A. Saxton ◽  
...  
Keyword(s):  
Healthy Aging ◽  
Population Based ◽  
Test Battery ◽  
Cognitive Test ◽  
Education Effects
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