scholarly journals Lemons to lemonade: Effects of a biobehavioral intervention for cancer patients on later life changes.

2019 ◽  
Vol 38 (3) ◽  
pp. 206-216 ◽  
Author(s):  
Claire C. Conley ◽  
Barbara L. Andersen
Keyword(s):  
Cancer Patients ◽  
Later Life ◽  
Life Changes ◽  
Biobehavioral Intervention

scholarly journals The microbiota-gut-brain axis: An emerging role for the epigenome

2019 ◽  
Vol 245 (2) ◽  
pp. 138-145 ◽  
Author(s):  
Tijs Louwies ◽  
Anthony C Johnson ◽  
Albert Orock ◽  
Tian Yuan ◽  
Beverley Greenwood-Van Meerveld
Keyword(s):  
Gut Microbiota ◽  
Neurological Disorders ◽  
Expression Patterns ◽  
Later Life ◽  
Epigenetic Modifications ◽  
Life Changes ◽  
Microbial Composition ◽  
Initial Stimulus ◽  
Bidirectional Communication ◽  
The Central Nervous System

Through the gut-brain axis, the microorganisms that reside in the gut are able to exert an important influence on the central nervous system. Preclinical and clinical evidence suggests that alterations in the composition of the gut microbiota are involved in gastrointestinal and neurological disorders. During critical neurodevelopmental time periods, such as the early life, changes in gut microbial composition may detrimentally impact neurodevelopment, and subsequently lead to neurological disorders in later life. The finding that neurological disorders persist suggests that epigenetic modifications may be involved in response to disruption of the microbiota-gut-brain axis. Through establishing epigenetic modifications, environmental (microbial) signals can interfere with the cellular gene expression patterns. These long-lasting modifications exert their effects even when the initial stimulus is removed. In this review, we discuss the pathways that provide bidirectional communication between the microbiota and the central and peripheral nervous systems. Furthermore, we summarize how these microorganisms in the gut exert their influence through changing the epigenome in the brain-gut axis. Impact statement Alterations in the composition of gut microbiota may influence the etiology of gastrointestinal and neurological disorders by disturbing the communication in the gut-brain axis. Epigenetic changes in the gut-brain axis may perpetuate these phenotypes even when the gut microbiota has been restored. The studies reviewed in this article provide an overview of the influence the microbiota exerts onto its host’s epigenome. First, we summarize the bidirectional pathways through which the microbiota and the gut-brain axis communicate. Second, we provide evidence for the epigenome-altering capacity of the gut microbiota. Finally, we address the existing knowledge gaps and highlight the potential role of the epigenome in the microbiota-gut-brain axis.

Revisiting Widowhood in Later Life: Changes in Patterns and Profiles, Advances in Research and Understanding

2011 ◽  
Vol 30 (3) ◽  
pp. 339-354 ◽  
Author(s):  
Anne Martin-Matthews
Keyword(s):  
Later Life ◽  
Life Changes ◽  
Fin De Vie ◽  
Classe Sociale ◽  
Marché Du Travail ◽  
Politique Sociale

RÉSUMÉCette analyse examine les façons dont l’expérience du veuvage dans la vieillesse ainsi que la nature de la recherche sur le veuvage ont changé depuis la publication du livre Le Veuvage en fin de vie en 1991. Les modèles de la baisse du veuvage sont examinés, à la fois dans sa durée et de son incidence retardée dans la vie. La recherche sur le veuvage a connu des avancées conceptuelles au-delà de la compréhension de la perte de rôle. La perspective du cours de la vie, ainsi que les concepts de narratifs multiples et de résilience ont aussi contribué à ce domaine. De nouvelles méthodes, y compris des méthodologies prospectives et longitudinales portant sur de larges ensembles de données, ainsi que des études qualitatives détaillées, ont fait avancer notre compréhension de la complexité et des variances du veuvage. Celles-ci incluent des variantes telles que le genre, la diversité ethnoculturelle et la combinaison de facteurs tels que l’aisance matérielle, la santé et la classe sociale. L’article examine aussi l’influence de l’affiliation au marché du travail, de la politique sociale et de la nature changeante du mariage sur le façonnement du veuvage plus tard au cours de la vie.

The appraisal of positive life changes following cancer diagnosis: An interview study

2006 ◽  
Vol 4 (1) ◽  
pp. 3-12 ◽  
Author(s):  
KAZUE KOMURA ◽  
JOHN R. HEGARTY
Keyword(s):  
Content Analysis ◽  
Cancer Patients ◽  
Healthy Lifestyle ◽  
Group Discussion ◽  
Future Research ◽  
Life Changes ◽  
Cancer Support ◽  
Cancer Support Group ◽  
Negative Impacts ◽  
Positive Impacts

Objective: This research examines positive life changes that cancer patients may experience following their diagnosis. Although cancer is often believed to have negative impacts on the life of patients, positive impacts have been also discussed empirically. This study focuses on cancer patients' appraisal of positive life changes following their diagnosis and examines how and in which fields they recognize their lives as positively changed based on the study of Petrie et al. (1999).Methods: A total of eight cancer patients in a cancer support group participated in this research. A group discussion and semistructured interviews were conducted. Content analysis was applied.Results: The content analysis produced insights into the seven types of cancer-related life changes: improved empathy, greater knowledge about health, renewed recognition of life, change in personal life priorities, greater appreciation of health and life, improved close relationships, and healthy lifestyle change. Negative life changes were also reported.Significance of the research: This research showed that cancer patients tended to find and appraise their own positive life changes following cancer. The categorization of positive life changes basically supported that of Petrie et al. (1999), but produced an original category: renewed recognition of life. Positive life changes might be seen as a natural process that encourages patients' adjustment to cancer. Understanding positive impacts of cancer could be important in capturing the life-sized features of cancer patients. Future research could expand the view of the impacts of cancer and demonstrate how people recognize them as benefits.

scholarly journals THE CONSTRUCT OF IDENTITY AMONG LATER LIFE CANCER PATIENTS

2015 ◽  
Vol 55 (Suppl_2) ◽  
pp. 55-55
Keyword(s):  
Cancer Patients ◽  
Later Life

Positive lifestyle changes following urological cancer diagnoses – an Australian interview based study

2015 ◽  
Vol 8 (2) ◽  
pp. 110-119 ◽  
Author(s):  
Sabina Cerimagic ◽  
Nariman Ahmadi ◽  
Howard Gurney ◽  
Tania Hossack ◽  
Manish I. Patel
Keyword(s):  
Posttraumatic Growth ◽  
Cancer Patients ◽  
Cancer Diagnosis ◽  
Ethnic Diversity ◽  
Small Sample ◽  
Lifestyle Changes ◽  
Life Changes ◽  
Structured Interviews ◽  
Urological Cancer ◽  
Content Type

Purpose – The purpose of this paper is to examine ethnic Australian urological cancer patients and the positive life changes that those patients report after cancer diagnosis. Design/methodology/approach – A sample of 50 Australian urological cancer patients of ethnic origin were chosen to participate in this study. One-on-one semi structured interviews were conducted with the patients. Findings – Cancer diagnosis often serves as an impetus for making positive lifestyle changes. Most (98 per cent) of this study’s participants reported that they made positive lifestyle changes following a diagnosis of cancer. Those positive lifestyle changes include: greater appreciation of health and life (100 per cent); improved diet (94 per cent); closer relationships with family and friends (90 per cent); more frequent visits to the doctor for check-ups (74 per cent); increased physical activity (48 per cent); starting a new hobby (36 per cent); greater knowledge about their health in general (32 per cent) and increased spirituality (22 per cent). Research limitations/implications – The limitation of this study is the small sample of patients with ethnic diversity specific to western Sydney. Larger multicentre studies across Australia are required to confirm the findings. Additionally, this study focused on positive life changes, because 98 per cent of the participants reported positive lifestyle changes after diagnosis. However, there are related negative health behaviour changes, which this study has not addressed in depth. Furthermore, a comparison between positive life changes of ethnic Australian patients’ against the experience of post cancer diagnosis of non-ethnic Australian patients could investigate this issue further and possibly provide further insight. Originality/value – The majority (98 per cent) of the participants report positive lifestyle changes following urological cancer diagnoses. The patient population of predominantly elderly (84 per cent), males (90 per cent) differs from the current literate which states that positive lifestyle changes (posttraumatic growth) are mainly found to be significantly correlated to being female, younger and non-white and greater event severity.

317. Quality of life changes during the adjuvant chemotherapy in colon cancer patients

2016 ◽  
Vol 42 (9) ◽  
pp. S145
Author(s):  
S.J. Lee ◽  
M.J. Baek ◽  
D.G. Park ◽  
T.G. Lee ◽  
J.Y. Kim
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Life Changes

scholarly journals MP05-01 HEALTH-RELATED QUALITY OF LIFE CHANGES IN PROSTATE CANCER PATIENTS AFTER RADICAL PROSTATECTOMY: A LONGITUDINAL COHORT STUDY

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Jinsung Park ◽  
Sang Hyub Lee ◽  
Tae-Hwan Kim ◽  
Seok Joong Yun ◽  
Jong Kil Nam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Cohort Study ◽  
Radical Prostatectomy ◽  
Cancer Patients ◽  
Life Changes ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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