scholarly journals Associations between breast adipose tissue, body fat distribution and cardiometabolic risk in women: cross-sectional data and weight-loss intervention

2011 ◽  
Vol 65 (7) ◽  
pp. 784-790 ◽  
Author(s):  
B Schautz ◽  
W Later ◽  
M Heller ◽  
M J Müller ◽  
A Bosy-Westphal
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Body Fat ◽  
Cardiometabolic Risk ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Weight Loss Intervention ◽  
Cross Sectional ◽  
Breast Adipose Tissue ◽  
Breast Adipose

scholarly journals Impact of age on leptin and adiponectin independent of adiposity

2012 ◽  
Vol 108 (2) ◽  
pp. 363-370 ◽  
Author(s):  
Britta Schautz ◽  
Wiebke Later ◽  
Martin Heller ◽  
Achim Peters ◽  
Manfred J. Müller ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Body Fat ◽  
Fat Distribution ◽  
Cross Sectional Study ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Cross Sectional ◽  
Age Related ◽  
A Minor ◽  
Age Related Changes

Age-related changes in leptin and adiponectin levels remain controversial, being affected by inconsistent normalisation for adiposity and body fat distribution in the literature. In a cross-sectional study on 210 Caucasians (127 women, eighty-three men, 18–78 years, BMI 16·8–46·8 kg/m2), we investigated the effect of age on adipokine levels independent of fat mass (FM measured by densitometry), visceral and subcutaneous adipose tissue volumes (VAT and SAT assessed by whole-body MRI). Adiponectin levels increased with age in both sexes, whereas leptin levels decreased with age in women only. There was an age-related increase in VAT (as a percentage of total adipose tissue, VAT%TAT), associated with a decrease in SATlegs%TAT. Adiposity was the main predictor of leptin levels, with 75·1 % of the variance explained by %FM in women and 76·6 % in men. Independent of adiposity, age had a minor contribution to the variance in leptin levels (5·2 % in women only). The variance in adiponectin levels explained by age was 14·1 % in women and 5·1 % in men. In addition, independent and inverse contributions to the variance in adiponectin levels were found for truncal SAT (explaining additional 3·0 % in women and 9·1 % in men) and VAT%TAT (explaining additional 13·0 % in men). In conclusion, age-related changes in leptin and adiponectin levels are opposite to each other and partly independent of adiposity and body fat distribution. Normalisation for adiposity but not for body fat distribution is required for leptin. Adiponectin levels are adversely affected by subcutaneous and visceral trunk fat.

scholarly journals Comparable reduction of the visceral adipose tissue depot after a diet-induced weight loss with or without aerobic exercise in obese subjects: a 12-week randomized intervention study

2009 ◽  
Vol 160 (5) ◽  
pp. 759-767 ◽  
Author(s):  
Tore Christiansen ◽  
Søren K Paulsen ◽  
Jens M Bruun ◽  
Kristian Overgaard ◽  
Steffen Ringgaard ◽  
...  
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Body Fat ◽  
Visceral Adipose Tissue ◽  
Weight Maintenance ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Hypocaloric Diet ◽  
Relative Reduction ◽  
Visceral Adipose

ObjectiveWeight loss with preferential effect on the visceral adipose tissue (VAT) depot could have important clinical benefits. In this study, we investigated the independent and combined effect of regular exercise and diet induced weight loss on body fat distribution.DesignRandomized control design of i) exercise-only (EXO; 12 weeks of exercise without diet-restriction), ii) hypocaloric-diet (DIO; 8 weeks of very low energy diet (VLED 600 kcal/day) followed by 4-weeks weight maintenance diet) and iii) hypocaloric-diet and exercise (DEX; 8 weeks VLED 800 kcal/day+a 4-week weight maintenance diet combined with exercise throughout the 12 weeks).SubjectsSeventy-nine obese males and females were included.MeasurementsBody fat distribution was quantified by magnetic resonance imaging (MRI)-technology.ResultsIn the EXO group, the weight loss (3.5 kg) and the relative reduction in VAT (18%) was significantly lower compared with the weight losses in the DIO and DEX groups (12.3 kg;P<0.01) and to the reduction in VAT (30–37%;P<0.01). In all the three groups, the relative reduction of VAT was higher as compared with the reduction in fat mass (FM; combining all fat depots determined by MRI;P<0.01 for all comparisons). The changes in VAT were associated with changes in FM and related to the initial VAT/FM ratio (r2=0.72;P<0.01).ConclusionExercise has no additional effects in reduction of the VAT depot, compared with the major effects of hypocaloric diet alone. In addition, the effects of exerciseper seon VAT are relatively limited. The effects on the VAT depot are closely associated with changes in total FM.

scholarly journals Body fat distribution in trunk and legs are associated with cardiometabolic risk clustering among Chinese adolescents aged 10–18 years old

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Qingmei Yang ◽  
Ping Ma ◽  
Hao Zhang ◽  
Rongrong Cai ◽  
Yangyang Dong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Fat ◽  
Fat Mass ◽  
Protective Factor ◽  
Cardiometabolic Risk ◽  
Fat Distribution ◽  
Normal Subjects ◽  
Body Fat Distribution ◽  
Chinese Adolescents ◽  
Cross Sectional

Abstract Objectives The aim of the present study was to evaluate the association of body fat distribution with cardiometabolic risk factors clustering among Chinese adolescents. Methods In this cross sectional study a total of 1,175 adolescents aged 10–18 years underwent a comprehensive assessment of cardimetabolic risk factors. Body fat analysis was performed with bioelectrical impedance analysis (BIA). Results Individuals with the CVRFs≥1 or CVRFs≥2 had higher indices of body fat distribution such as body fat mass (BFM) compared to those with normal CVRFs (all p<0.001). The prevalence of CVRFs≥1, CVRFs≥2 increased with increasing of the quartile of BFM, TBFM, ABFM, LBFM, PBF, VFL compared to normal subjects. After adjusted for age and sex, the study indicated an linear relationship between TBFM (β = 0.693, 95% CI:0.363, 1.023), LBFM (β = −1.471, 95% CI:−2.768, −0.175) and CVRFs z-score. Logistic regression models suggested TBFM was associated with CVRFs≥1 and CVRFs≥2 by higher odds. Lower odds of LBFM was associated with CVRFs≥2. Conclusions The contribution of the fat mass in specific region on the cardiovascular risk factors clustering is different among adolescents. The trunk fat is associated with higher clustered cardiometabolic risk, while leg fat mass is the protective factor.

scholarly journals AKR1C2 and AKR1C3 expression in adipose tissue: association with body fat distribution and regulatory variants

2021 ◽  
pp. 111220
Author(s):  
Giada Ostinelli ◽  
Jinchu Vijay ◽  
Marie-Claude Vohl ◽  
Elin Grundberg ◽  
Andre Tchernof
Keyword(s):  
Adipose Tissue ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Regulatory Variants

scholarly journals Impact of Variation in the FTO Gene on Whole Body Fat Distribution, Ectopic Fat, and Weight Loss

Obesity ◽  
2008 ◽  
Vol 16 (8) ◽  
pp. 1969-1972 ◽  
Author(s):  
Axel Haupt ◽  
Claus Thamer ◽  
Jürgen Machann ◽  
Kerstin Kirchhoff ◽  
Norbert Stefan ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Whole Body ◽  
Ectopic Fat ◽  
Fto Gene

scholarly journals Unacylated ghrelin is associated with changes in body composition and body fat distribution during long-term exercise intervention

2011 ◽  
Vol 165 (2) ◽  
pp. 243-248 ◽  
Author(s):  
Henna Cederberg ◽  
Ulla Rajala ◽  
Vesa-Matti Koivisto ◽  
Jari Jokelainen ◽  
Heljä-Marja Surcel ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Waist Circumference ◽  
Body Fat ◽  
Exercise Performance ◽  
Exercise Intervention ◽  
Fat Distribution ◽  
Body Fat Distribution ◽  
Unacylated Ghrelin

ObjectiveGhrelin, a gut–brain peptide involved in energy homeostasis, circulates predominantly (>90%) in unacylated form. Previous studies, however, have focused on total and acylated ghrelin, and the role of unacylated ghrelin (UAG) is not well understood. Particularly, the association of UAG with weight loss and changes in body composition in adults remains unclear. We hypothesized that exercise-associated increase in UAG level is associated with weight loss, favorable changes in body composition, and body fat distribution.Design and methodsA prospective study of 552 young men (mean age 19.3 and range 19–28 years) undergoing military service with structured 6-month exercise training program. Exercise performance, body composition, and biochemical measurements were obtained at baseline and follow-up. Association between changes in UAG levels and body composition and body fat distribution were evaluated.ResultsAn increase in UAG level during the exercise intervention was associated with reduced weight, fat mass (FM), fat percentage (fat %), and waist circumference, but not with fat-free mass. Inverse associations of changes in UAG level with changes in waist circumference and fat % were independent of weight at baseline, and changes in weight and exercise performance. Associations of changes in UAG level with waist circumference were significantly stronger than with fat % after the adjustment for confounding variables.ConclusionUAG is associated with changes in body weight and body composition during an intensive long-term exercise intervention in young men. The association of UAG levels with changes in central obesity was stronger than with total FM.

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