Assessing temporal eating pattern in free living humans through the myCircadianClock app

Abstract Objectives Subject compliance in free-living dietary intervention studies is difficult to achieve. Published studies suggest various theoretically based strategies that can be used to improve compliance. Methods A weight-management dietary intervention for free-living subjects, based on a vegetarian dietary pattern, was created. Development of 7-day menus was conducted using McGraw Hills’ NutritionCalc Plus software. Menus utilized a framework from the 2015–2020 Dietary Guidelines for Americans’ Healthy Vegetarian Eating Pattern (macronutrient ratios and food group servings). A literature review was conducted to identify various counseling and technology strategies that may be effective at increasing subject compliance with their assigned study diet. The findings of the literature review was used to create study protocols. Protocol development for a food demonstration was also explored. Results A 1-week menu cycle for a vegetarian diet intervention was created, including a set of menus each for 1200,1800, and 2000 calories levels. The menus are inclusive of foods and portions that meet the Dietary Guidelines for Americans. Three study protocols were developed for strategies that may improve subject compliance: 1. A nutrition counseling protocol based on motivational interviewing; 2. A technology protocol on use of a dietary-self monitoring app; and 3. A food demonstration protocol highlighting vegetarian recipes. The protocols are designed to be used by study clinicians/dietitians in future intervention studies. Conclusions Theory-based protocols can be used to develop standardized protocols for research studies. These protocols theoretically may help to improve subject compliance. Funding Sources NIH BUILD PODER.

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Adherence in a 1-year whole foods eating pattern intervention with healthy postmenopausal women

Public Health Nutrition ◽

10.1017/s1368980014000044 ◽

2014 ◽

Vol 17 (12) ◽

pp. 2806-2815 ◽

Cited By ~ 5

Author(s):

Nancy Champe Peters ◽

Isobel R Contento ◽

Fredi Kronenberg ◽

Marci Coleton

Keyword(s):

Postmenopausal Women ◽

Cognitive Theory ◽

Dietary Intervention ◽

Controlled Trial ◽

Eating Patterns ◽

Free Living ◽

Eating Pattern ◽

Adherence Score ◽

Study Characteristics ◽

Whole Foods

AbstractObjectiveTo determine the degree of dietary adherence or change in eating patterns, and demographic, psychosocial and study characteristics associated with adherence, in the Comparing Healthy Options in Cooking and Eating (CHOICE) Study.DesignRandomized controlled trial where women were randomized to one of three eating patterns: (i) Whole Foods, plant-based, macrobiotic-style (n 22); and Moderate Fat with (ii), and without (iii), 10 g of ground flaxseed added daily, which were combined (n 49).SettingA year-long intervention based on social cognitive theory, consisting of twenty-four class sessions involving hands-on cooking classes and behavioural sessions. Monthly 24 h food recalls were obtained and a psychosocial questionnaire was administered at baseline, 6 and 12 months.SubjectsHealthy, free-living, postmenopausal women.ResultsA non-adherence score measuring all food servings out-of-compliance with eating pattern recommendations was specifically designed for the present study. Non-adherence scores decreased significantly (P < 0·05) in both groups to about 65 % during the adoption phase (first 4 months) and remained so during the 8-month maintenance period. Class attendance of the Moderate Fat group showed a trend towards significance as a predictor of adherence (P = 0·063). None of the other predictors (e.g. demographic and psychosocial factors) in a longitudinal regression model were significant.ConclusionsPostmenopausal women were able to adopt and maintain significant changes in their eating patterns, including those on a demanding, near-vegetarian eating plan, suggesting that behavioural interventions with a healthy free-living population can be effective. The non-adherence score developed for the study provides an example of a means for evaluating eating pattern adherence to a dietary intervention.

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Within-person compensation for snack energy by US adults, NHANES 2007–2014

American Journal of Clinical Nutrition ◽

10.1093/ajcn/nqy349 ◽

2019 ◽

Vol 109 (4) ◽

pp. 1145-1153 ◽

Cited By ~ 4

Author(s):

Ashima K Kant ◽

Barry I Graubard

Keyword(s):

Energy Intake ◽

Eating Behaviors ◽

Positive Energy ◽

Natural Setting ◽

Free Living ◽

Eating Pattern ◽

Men And Women ◽

Dietary Recall ◽

Nutrition Study ◽

Main Meals

ABSTRACT Background Most Americans snack and some snack several times a day; however, compensatory dietary and eating behaviors associated with snacking in free-living individuals are poorly understood. Objective The aim of the study was to examine within-person differences in reported energy intake and eating patterns on a snack day relative to a no-snack day. Methods We used 2 d of dietary recall data from the NHANES 2007–2014 to replicate the crossover nutrition study paradigm in a natural setting. Respondents reporting a snack episode in only one of two available dietary recalls were eligible for inclusion in the study (n = 1,917 men and 1,860 women). We used multivariable regression methods to compare within-person differences in quantitative, qualitative, and eating pattern outcomes between the snack and no-snack recall days. Results On the snack day, snack episodes provided (mean difference and 95% CI) 493 (454, 532) kcal of energy in men and 360 (328, 392) kcal in women. The 24-h energy intake on snack day was higher by 239 (140, 337) kcal in men and 219 (164, 273) kcal in women (P < 0.0001). On the snack day, both men and women were more likely to skip main meals and reported lower energy intake from main meals (P < 0.0001); however, the energy density of foods or beverages reported on the snack compared with no-snack days were not different. Fruit servings were higher on the snack day (P ≤ 0.0004), but intakes of vegetables and key micronutrients did not differ. The 24-h ingestive period was longer on the snack day (P < 0.0001). Conclusions Free-living men and women partially compensated for snack energy by decreasing energy intake from main meals without adverse associations with qualitative dietary characteristics or time of meal consumption. Women compensated to a smaller extent than men. Thus, over the long term, snack episodes may contribute to positive energy balance, and the risk may be higher in women.

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Ultrastructure of neuromuscular relationships in the canine heartworm (dirofilaria immitis)

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100143018 ◽

1986 ◽

Vol 44 ◽

pp. 278-279

Author(s):

W. L. Steffens ◽

Nancy B. Roberts ◽

J. M. Bowen

Keyword(s):

Dirofilaria Immitis ◽

Domestic Dogs ◽

Structural Description ◽

Pharmacological Effects ◽

Free Living ◽

Canine Heartworm ◽

The World ◽

Synaptic Region ◽

Muscle Innervation ◽

Insight Into

The canine heartworm is a common and serious nematode parasite of domestic dogs in many parts of the world. Although nematode neuroanatomy is fairly well documented, the emphasis has been on sensory anatomy and primarily in free-living soil species and ascarids. Lee and Miller reported on the muscular anatomy in the heartworm, but provided little insight into the peripheral nervous system or myoneural relationships. The classical fine-structural description of nematode muscle innervation is Rosenbluth's earlier work in Ascaris. Since the pharmacological effects of some nematacides currently being developed are neuromuscular in nature, a better understanding of heartworm myoneural anatomy, particularly in reference to the synaptic region is warranted.

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Lead and lead toxicity in domestic and free living birds

Avian Pathology ◽

10.1080/03079450301777 ◽

2003 ◽

Vol 32 (1) ◽

pp. 3-13 ◽

Cited By ~ 1

Author(s):

N. De Francisco ◽

N. De Francisco

Keyword(s):

Lead Toxicity ◽

Free Living

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Platelet Aggregation in Finnish Men and Its Relation to Fatty Acids in Platelets, Plasma and Adipose Tissue

Thrombosis and Haemostasis ◽

10.1055/s-0038-1660071 ◽

1985 ◽

Vol 54 (03) ◽

pp. 563-569 ◽

Cited By ~ 19

Author(s):

M K Salo ◽

E Vartiainen ◽

P Puska ◽

T Nikkari

Keyword(s):

Fatty Acids ◽

Adipose Tissue ◽

Fatty Acid Composition ◽

Fatty Acid ◽

Platelet Aggregation ◽

Acid Composition ◽

Saturated Fatty Acids ◽

Free Living ◽

Ω3 Fatty Acids ◽

Induced Aggregation

SummaryPlatelet aggregation and its relation to fatty acid composition of platelets, plasma and adipose tissue was determined in 196 randomly selected, free-living, 40-49-year-old men in two regions of Finland (east and southwest) with a nearly twofold difference in the IHD rate.There were no significant east-southwest differences in platelet aggregation induced with ADP, thrombin or epinephrine. ADP-induced platelet secondary aggregation showed significant negative associations with all C20-C22 ω3-fatty acids in platelets (r = -0.26 - -0.40) and with the platelet 20: 5ω3/20: 4ω 6 and ω3/ ω6 ratios, but significant positive correlations with the contents of 18:2 in adipose tissue (r = 0.20) and plasma triglycerides (TG) (r = 0.29). Epinephrine-induced aggregation correlated negatively with 20: 5ω 3 in plasma cholesteryl esters (CE) (r = -0.23) and TG (r = -0.29), and positively with the total percentage of saturated fatty acids in platelets (r = 0.33), but had no significant correlations with any of the ω6-fatty acids. Thrombin-induced aggregation correlated negatively with the ω3/6ω ratio in adipose tissue (r = -0.25) and the 20: 3ω6/20: 4ω 6 ratio in plasma CE (r = -0.27) and free fatty acids (FFA) (r = -0.23), and positively with adipose tissue 18:2 (r = 0.23) and 20:4ω6 (r = 0.22) in plasma phospholipids (PL).The percentages of prostanoid precursors in platelet lipids, i. e. 20: 3ω 6, 20: 4ω 6 and 20 :5ω 3, correlated best with the same fatty acids in plasma CE (r = 0.32 - 0.77) and PL (r = 0.28 - 0.74). Platelet 20: 5ω 3 had highly significant negative correlations with the percentage of 18:2 in adipose tissue and all plasma lipid fractions (r = -0.35 - -0.44).These results suggest that, among a free-living population, relatively small changes in the fatty acid composition of plasma and platelets may be reflected in significant differences in platelet aggregation, and that an increase in linoleate-rich vegetable fat in the diet may not affect platelet function favourably unless it is accompanied by an adequate supply of ω3 fatty acids.

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