Early childhood body mass index trajectory and overweight/obesity risk differed by maternal weight status

The objective of this study was to determine the associations between hypertensive disorders of pregnancy and early childhood cardiometabolic risk factors in the offspring. Therefore, 7794 women from the Generation Rotterdam Study were included, an ongoing population-based prospective birth cohort. Women with a hypertensive disorder of pregnancy were classified as such when they were affected by pregnancy induced hypertension, pre-eclampsia or the haemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome during pregnancy. Early childhood cardiometabolic risk factors were defined as the body mass index at the age of 2, 6, 12, 36 months and 6 years. Additionally, it included systolic blood pressure, diastolic blood pressure, total fat mass, cholesterol, triglycerides, insulin and clustering of cardiometabolic risk factors at 6 years of age. Sex-specific differences in the associations between hypertensive disorders and early childhood cardiometabolic risk factors were investigated. Maternal hypertensive disorders of pregnancy were inversely associated with childhood body mass index at 12 months (confounder model: -0.15 SD, 95% CI -0.27; -0.03) and childhood triglyceride at 6 years of age (confounder model: -0.28 SD, 95% CI -0.45; -0.10). For the association with triglycerides, this was only present in girls. Maternal hypertensive disorders of pregnancy were not associated with childhood body mass index at 2, 6 and 36 months. No associations were observed between maternal hypertensive disorders of pregnancy and systolic blood pressure, diastolic blood pressure, body mass index, fat mass index and cholesterol levels at 6 years of age. Our findings do not support an independent and consistent association between maternal hypertensive disorders of pregnancy and early childhood cardiometabolic risk factors in their offspring. However, this does not rule out possible longer term effects of maternal hypertensive disorders of pregnancy on offspring cardiometabolic health.

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Prenatal Stress and Early Childhood Body Mass Index: A Path Analysis Approach

Maternal and Child Health Journal ◽

10.1007/s10995-020-03060-9 ◽

2021 ◽

Author(s):

Charlotte V. Farewell ◽

Jini Puma ◽

Zaneta M. Thayer ◽

Susan Morton

Keyword(s):

Body Mass Index ◽

Early Childhood ◽

Path Analysis ◽

Body Mass ◽

Prenatal Stress ◽

Analysis Approach ◽

Childhood Body Mass Index ◽

Path Analysis Approach

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Cesarean birth is not associated with early childhood body mass index

Pediatric Obesity ◽

10.1111/ijpo.12180 ◽

2016 ◽

Vol 12 ◽

pp. 120-124 ◽

Cited By ~ 6

Author(s):

L. G. Smithers ◽

B. W. Mol ◽

L. Jamieson ◽

J. W. Lynch

Keyword(s):

Body Mass Index ◽

Early Childhood ◽

Body Mass ◽

Cesarean Birth ◽

Childhood Body Mass Index

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Prenatal antimicrobial use and early-childhood body mass index

International Journal of Obesity ◽

10.1038/ijo.2017.205 ◽

2017 ◽

Vol 42 (1) ◽

pp. 1-7 ◽

Cited By ~ 19

Author(s):

A E Cassidy-Bushrow ◽

C Burmeister ◽

S Havstad ◽

A M Levin ◽

S V Lynch ◽

...

Keyword(s):

Body Mass Index ◽

Early Childhood ◽

Body Mass ◽

Antimicrobial Use ◽

Childhood Body Mass Index

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Associations Between Delivery Mode and Early Childhood Body Mass Index Z-Score Trajectories: A Retrospective Analysis of 2,685 Children From Mothers Aged 18 to 35 Years at Delivery

Frontiers in Pediatrics ◽

10.3389/fped.2020.598016 ◽

2020 ◽

Vol 8 ◽

Author(s):

Lihong Zhang ◽

Liuxia Huang ◽

Zhiyuan Zhao ◽

Renjuan Ding ◽

Hongnian Liu ◽

...

Keyword(s):

Body Mass Index ◽

Early Childhood ◽

Body Mass ◽

Measurement Data ◽

Anthropometric Measurement ◽

Delivery Mode ◽

Z Score ◽

Childhood Body Mass Index ◽

Logistic Regressions ◽

Birth Data

Objective: To investigate the association between cesarean delivery (CD) and trajectory patterns of age- and sex-specific body mass index (BMI) z-score in early childhood.Methods: A retrospective cohort study was conducted among 2,685 children whose maternal age at the time of birth was between 18 and 35 years, and birth data and anthropometric measurement data during their ages 3–60 months were collected. A group-based trajectory modeling approach was used to identify distinct BMI z-score trajectories, and multinomial logistic regressions were applied to estimate the associations among CD (both elective and non-elective combined), elective and non-selective CD, and BMI z-score trajectory classes.Results: Of the 2,685 participants, 46.5% (N = 1,248) were born by vaginal delivery (VD), 20.7% (N = 556) by elective CD, and 32.8% (N = 881) by non-elective CD. Five BMI z-score trajectory patterns were identified, and they were “increasing from moderate to high” (10.1%, n = 270), “increasing from mild to moderate” (34.2%, n = 919), “increasing from low to high” (10.5%, n = 283), “stable mild” (30.1%, n = 808), and “stable low” (15.1%, n = 405) groups. Compared with children delivered by VD, those who delivered by CD (both elective and non-elective combined), elective CD, and non-elective CD were associated with the “increasing from moderate to high” trajectory [odds ratio (OR) = 1.61, 95% confidence interval (CI): 1.13–2.29; OR = 1.64, 95%CI: 1.06–2.54; and OR = 1.59, 95%CI: 1.05–2.39, respectively] and were also associated with the “increasing from low to high” trajectory (OR = 1.60, 95%CI: 1.17–2.19, OR = 1.75, 95%CI: 1.16–2.63; and OR = 1.53, 95%CI: 1.00–2.34, respectively).Conclusion: Both elective and non-elective CD were associated with the risk of accelerated weight gain in early childhood.

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Relationship between Severe Early Childhood Caries and Body Mass Index

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.37.3.u56q1554r67g4g31 ◽

2013 ◽

Vol 37 (3) ◽

pp. 235-242 ◽

Cited By ~ 10

Author(s):

W Bhoomika ◽

Ramakrishna Y ◽

AK Munshi

Keyword(s):

Body Mass Index ◽

Early Childhood ◽

Body Weight ◽

Body Mass ◽

Early Childhood Caries ◽

Weight Status ◽

The Body ◽

Body Weight Status ◽

Severe Early Childhood Caries ◽

Childhood Caries

Aim: This study was undertaken to evaluate the relationship between Severe Early Childhood Caries (S-ECC) and Body Mass Index (BMI) in the absence of any underlying medical condition for the school going (3 to 6 years old) children of Mathura city, India. Method: One hundred caries free children (50 boys and 50 girls) and one hundred children (50 boys and 50 girls) affected with S-ECC in the age range of 3-6 years without any contributing medical history were included in the study. Measurements of the weight (kg) and height (m) were done using a standard balanced beam scale and stadiometer. The BMI (kg/m2) was determined and the body weight status was evaluated using CDC based classification for each child. Independent t-test was used to evaluate whether the weight, height and BMI of S-ECC children is significantly different from caries free children. Result: Although the weight of the S-ECC children is more when compared to the normal children, the difference is not statistically significant. However, the mean BMI of S-ECC children is more when compared to the caries free children which was found to be statistically significant at p<0.05. The body weight status of the Normal and S-ECC affected children based on the CDC classification revealed that 48% have been classified in underweight category and 43% in normal weight category and very few children are found to be at risk of overweight and overweight. Conclusions: A positive correlation between the BMI and S-ECC was observed in this study. 51% of caries free children and 45% of S-ECC children were classified in underweight category based on CDC classification.

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