Familial History of Diabetes is Associated with Poor Glycaemic Control in Type 2 Diabetics: A Cross-sectional Study

Objectives: This study aimed to explore the relationship between glycaemic control and factors that may influence this among elderly type 2 diabetes mellitus (T2DM) patients in Lahore, Pakistan. Methods: This descriptive, cross-sectional study was conducted at the Jinnah and Sir Ganga Ram Hospitals, Lahore using convenience sampling techniques between 1 December 2015 and 28 February 2016. The sample consisted of elderly (>65 years) T2DM patients. Glycaemic values and patient characteristics were obtained from medical charts. Consenting patients were interviewed to complete the Barthel Index, Lawton Instrumental Activities of Daily Living Scale, Clinical Frailty Scale, Iowa Pain Thermometer Scale, Geriatric Depression Scale, Montreal Cognitive Assessment tool, Mini Nutritional Assessment Scale—Short Form and Self Care Inventory—Revised Version. Multiple logistic regression analysis was carried out to determine the predictors of poor glycaemic control. Results: A total of 490 patients were approached and 400 agreed to participate. Overall, nearly one-third (32.2%, n = 129) of patients had glycated haemoglobin (HbA1c) at the target level. Fasting and random plasma glucose levels were within the target range to much the same extent; (36.8%, n = 147) and (27%, n = 108), respectively. HbA1c levels were also higher in patients with co-morbidities (67.4%, n = 229) with diabetes-related complications (73.5%, n = 227). Significant predictors of impaired glycaemic control (HbA1c) included poor diabetes self-care (adjusted odds ratio (AOR) 0.96; 95% confidence interval (CI) 0.95, 0.98), not being prescribed oral hypoglycaemic agents (OHA) (AOR 6.22; 95% CI 2.09, 18.46), regular hypoglycaemic attacks (AOR 2.53; 95% CI 1.34, 4.81) and falling tendency (AOR 0.19; 95% CI 0.10, 0.36). Conclusions: Poor glycaemic control prevailed among the majority of elderly Pakistani diabetic patients in this study. Triggering factors of poor glycaemic control should be taken into consideration by the healthcare professionals in targeting multifaceted interventions to achieve good glycaemic control.

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Self-Care Adherence And Barriers To Good Glycaemic Control In Nepalese Type 2 Diabetes Mellitus Patients: A Hospital-Based Cross-Sectional Study

Journal of Multidisciplinary Healthcare ◽

10.2147/jmdh.s216842 ◽

2019 ◽

Vol Volume 12 ◽

pp. 817-826 ◽

Cited By ~ 2

Author(s):

Sushant Pokhrel ◽

Sneha Shrestha ◽

Alaska Timilsina ◽

Manisha Sapkota ◽

Mahendra Prasad Bhatt ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Glycaemic Control ◽

Self Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Good Glycaemic Control

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Lipid profile abnormalities in newly diagnosed type 2 diabetics: a cross-sectional study

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20193620 ◽

2019 ◽

Vol 6 (5) ◽

pp. 1452

Author(s):

Monica A. ◽

Dhivya P.

Keyword(s):

Cardiovascular Disease ◽

Lipid Profile ◽

Cross Sectional Study ◽

South Indian Population ◽

Newly Diagnosed ◽

Sectional Study ◽

Cross Sectional ◽

Type 2 Diabetics ◽

Very High

Background: India is fast becoming the diabetes capital of the World. A direct atherogenic effect of triglyceride rich particles has been noted. This study assesses the lipid profile abnormalities in newly diagnosed type 2 diabetes mellitus. Since dyslipidemia is a risk factor for cardiovascular disease, such assessment will enable better recognition, prevention and management of cardiovascular mortality and morbidity.Methods: The study was conducted over a period of one year at a tertiary care hospital in South India. A cross-sectional study of 100 newly diagnosed type 2 diabetics in a rural South-Indian population was done. Results: In our study, 55 (55%) participants had high triglycerides and 45 (45%) had normal triglycerides. Among the 55 participants with abnormal triglycerides, 34% had borderline high levels (150-199mg/dl), 18% had high levels (200-499 mg/dl) and 3% participants had very high triglycerides (≥500 mg/dl). 26% male and 29% female participants had above normal triglyceride levels. In our study, 25% had borderline high cholesterol levels and 5% had high total Cholesterol. 39% of participants had near optimal levels of LDL, 19% had borderline high levels of LDL, 7% had high levels of LDL and 4% had very high levels of LDL. Significantly higher levels of triglycerides and LDL were noted.Conclusions: Deranged lipid profiles are quite prevalent in type 2 diabetics with females having higher triglyceride levels. Recognition of such elevated triglyceride levels in even newly diagnosed type 2 diabetics will help in better prevention of associated cardiovascular disease.

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Correlation of Glycemic and Lipid Control Parameters with Cognitive Dysfunction Scores, in Type 2 Diabetic Persons Results from a cross- sectional study

Revista de Chimie ◽

10.37358/rc.18.12.6775 ◽

2019 ◽

Vol 69 (12) ◽

pp. 3486-3489

Author(s):

Gina Botnariu ◽

Alina Popa ◽

Geta Mitrea ◽

Marius Manole ◽

Mariana Pacurar ◽

...

Keyword(s):

Cognitive Dysfunction ◽

Cross Sectional Study ◽

The Body ◽

Sectional Study ◽

Cross Sectional ◽

Type 2 Diabetics ◽

Lipid Control ◽

High Density Cholesterol ◽

The Relationship

Diabetes-related cognitive dysfunction is considered a long-term complication of diabetes. In this cross-sectional study was studied the relationship between cognitive dysfunction (assessed by using two standardized questionnaires), lipid profile parameters and fatty free acids intake, in outpatients, hospitalized for their periodical control. The Mini-Mental State Exam (MMSE) and The Montreal Cognitive Assessment (MoCA) score were related to the body mass index (BMI), high density cholesterol (HDLc), glycated hemoglobin (Hb A1c) and intake of choline and eicosapentaenoic acid (all Ps [ .05, excepting the relationship between MMSE and HDLc). The implications of FFA intake in dementia development, in type 2 diabetics, is important for disease management and prevention.

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Hypomagnesemia and Poor Glycemic Control Among Palestinian Type 2 Diabetic Patients: A Cross-Sectional Study

10.21203/rs.3.rs-1066121/v1 ◽

2021 ◽

Author(s):

Mohmmad Hamarshih ◽

Suha Hamshari ◽

Zaher Nazzal ◽

Farha Abu Snobar ◽

Rawa Mletat ◽

...

Keyword(s):

Diabetic Retinopathy ◽

Glycemic Control ◽

Serum Magnesium ◽

Cross Sectional Study ◽

Magnesium Level ◽

Poor Glycemic Control ◽

Sectional Study ◽

Cross Sectional ◽

History Of

Abstract Background: Hypomagnesemia has been shown to have a significant impact on both glycemic control and diabetes complications in type 2 Diabetes Mellitus (T2DM) patients. This study aims to assess the prevalence of hypomagnesemia in T2DM patients and find the association between serum magnesium levels and outcomes relevant to glycemic control and diabetic complications.Methods: A cross-sectional study was conducted and included 373 patients (222 males and 151 females). Serum magnesium levels were measured by the Colorimetric Endpoint Method using the Cobas C501system. Hypomagnesemia was determined to be a serum magnesium level <1.6 mg/dL. In addition, the following data were also obtained; patients' characteristics, anthropometric measurements, smoking status, HbA1c, co-morbidities, and therapeutic management. Results: Patients' mean age was 56.2 ±10.8 years, 24.6% were smokers, and most were overweight or obese. About 60% have a history of hypertension, and the majority have had diabetes for more than ten years. Their mean HbA1c level was 8.5±2. The prevalence of hypomagnesemia was 11% (95% CI: 8%-14.6%). It was found to be significantly higher among females (adjusted OR: 2.7, 95%CI: 1.2%-5.8%), patients with HbA1c ≥ 8% (adjusted OR: 2.4, 95%CI: 1.1%-5.5%), and patients with a history of diabetic retinopathy (adjusted OR: 2.7, 95%CI: 1.1%-7.1%). Conclusions: the study showed that hypomagnesemia is more prevalent in females and is associated with diabetic retinopathy and poor glycemic control. Having a sufficient magnesium level may be associated with better glycemic control and a reduced occurrence of complications.

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Dietary Intakes And Familial History of Obesity

Canadian Journal of Dietetic Practice and Research ◽

10.3148/69.2.2008.97 ◽

2008 ◽

Vol 69 (2) ◽

pp. 97-100 ◽

Cited By ~ 2

Author(s):

Ann-Marie Paradis ◽

Gaston Godin ◽

Louis Pérusse ◽

Marie-Claude Vohl

Keyword(s):

Cross Sectional Study ◽

Dietary Guidelines ◽

Quebec City ◽

Dietary Intakes ◽

Sectional Study ◽

Cross Sectional ◽

Familial History ◽

Daily Energy ◽

History Of ◽

History Of Obesity

Purpose: To compare dietary intakes of individuals with and without familial history of obesity (FHO) with recommendations from Canada’s Food Guide to Healthy Eating (CFGHE). Methods: This cross-sectional study recruited 197 women and 129 men with a body mass index of less than 30kg/m2 from the Quebec City metropolitan area. A dietitian obtained their dietary intakes, using a food frequency questionnaire. Results: Daily energy, macronutrient, and fibre intakes were not significantly different between individuals with and without FHO. No significant differences in the proportion of individuals who achieved the minimum CFGHE recommendations were observed between individuals with and without FHO. Conclusions: Findings of our study suggest that individuals with and without FHO have comparable dietary intakes when compared to Canadian dietary guidelines.

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