scholarly journals Correlation of Glycemic and Lipid Control Parameters with Cognitive Dysfunction Scores, in Type 2 Diabetic Persons Results from a cross- sectional study

2019 ◽  
Vol 69 (12) ◽  
pp. 3486-3489
Author(s):  
Gina Botnariu ◽  
Alina Popa ◽  
Geta Mitrea ◽  
Marius Manole ◽  
Mariana Pacurar ◽  
...  
Keyword(s):  
Cognitive Dysfunction ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Diabetics ◽  
Lipid Control ◽  
High Density Cholesterol ◽  
The Relationship

Diabetes-related cognitive dysfunction is considered a long-term complication of diabetes. In this cross-sectional study was studied the relationship between cognitive dysfunction (assessed by using two standardized questionnaires), lipid profile parameters and fatty free acids intake, in outpatients, hospitalized for their periodical control. The Mini-Mental State Exam (MMSE) and The Montreal Cognitive Assessment (MoCA) score were related to the body mass index (BMI), high density cholesterol (HDLc), glycated hemoglobin (Hb A1c) and intake of choline and eicosapentaenoic acid (all Ps [ .05, excepting the relationship between MMSE and HDLc). The implications of FFA intake in dementia development, in type 2 diabetics, is important for disease management and prevention.

scholarly journals Lipid profile abnormalities in newly diagnosed type 2 diabetics: a cross-sectional study

2019 ◽  
Vol 6 (5) ◽  
pp. 1452
Author(s):  
Monica A. ◽  
Dhivya P.
Keyword(s):  
Cardiovascular Disease ◽  
Lipid Profile ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Newly Diagnosed ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Diabetics ◽  
Very High

Background: India is fast becoming the diabetes capital of the World. A direct atherogenic effect of triglyceride rich particles has been noted. This study assesses the lipid profile abnormalities in newly diagnosed type 2 diabetes mellitus. Since dyslipidemia is a risk factor for cardiovascular disease, such assessment will enable better recognition, prevention and management of cardiovascular mortality and morbidity.Methods: The study was conducted over a period of one year at a tertiary care hospital in South India. A cross-sectional study of 100 newly diagnosed type 2 diabetics in a rural South-Indian population was done. Results: In our study, 55 (55%) participants had high triglycerides and 45 (45%) had normal triglycerides.  Among the 55 participants with abnormal triglycerides, 34% had borderline high levels (150-199mg/dl), 18% had high levels (200-499 mg/dl) and 3% participants had very high triglycerides (≥500 mg/dl). 26% male and 29% female participants had above normal triglyceride levels. In our study, 25% had borderline high cholesterol levels and 5% had high total Cholesterol. 39% of participants had near optimal levels of LDL, 19% had borderline high levels of LDL, 7% had high levels of LDL and 4% had very high levels of LDL. Significantly higher levels of triglycerides and LDL were noted.Conclusions: Deranged lipid profiles are quite prevalent in type 2 diabetics with females having higher triglyceride levels. Recognition of such elevated triglyceride levels in even newly diagnosed type 2 diabetics will help in better prevention of associated cardiovascular disease.

scholarly journals Type 2 diabetes mellitus in glucose-6-phosphate dehydrogenase deficient individuals in a Ghanaian population

2020 ◽  
Vol 8 (12) ◽  
pp. 4348
Author(s):  
Perez Quartey ◽  
Bright Afriyie Owusu ◽  
Daniel Taylor ◽  
Eliza-Bertha Adomaka
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
G6pd Deficiency ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chi Square Analysis ◽  
The Relationship

Background: Studies in different populations have shown an association between diabetes mellitus and G6PD deficiency. This association has not been investigated in the Ghanaian population. We conducted a cross-sectional study to investigate the relationship between G6PD deficiency and type 2 diabetes mellitus in a Ghanaian population.Methods: The cross-sectional study involved 125 registered type 2 diabetes mellitus clients and 125 non-diabetic individuals. Chi-square analysis was used to assess the association between G6PD status and type 2 diabetes mellitus with statistical significance pegged at p-value<0.05.Results: The prevalence of G6PD deficiency in the study population was 24.0% and 13.6% for the diabetics and non-diabetics respectively. In terms of gender, 29.5% of the diabetic males were G6PD deficient whiles G6PD deficiency was observed in 11.1% of the non-diabetic males. Additionally, 21.0% of the diabetic females were also G6PD deficient with 15.3% of the non-diabetic females being G6PD deficient. The results showed that the overall G6PD deficiency was significantly associated with type 2 diabetes mellitus as compared to the non-diabetics. In terms of gender differences, G6PD deficiency was significantly associated with type 2 diabetes in males but, there was no significant association in females.Conclusions: The study reports the first findings of the relationship between G6PD deficiencies among type 2 diabetes patients in Ghana. The study revealed that G6PD deficiency is more prevalent among type 2 diabetics than non-diabetics. Type 2 diabetes mellitus is independently associated with G6PD deficiency in males but not females.

scholarly journals A Pilot Study on the Effect of Anti-Thrombopoietin Antibody on Platelet Count in Patients with Type 2 Diabetes

Molecules ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 1667
Author(s):  
Takuya Fukuda ◽  
Masahide Hamaguchi ◽  
Takafumi Osaka ◽  
Yoshitaka Hashimoto ◽  
Emi Ushigome ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Platelet Count ◽  
Cross Sectional Study ◽  
Regression Analyses ◽  
Sectional Study ◽  
Cross Sectional ◽  
Platelet Production ◽  
The Relationship

Thrombopoietin (THPO) is a circulatory cytokine that plays an important role in platelet production. The presence of anti-THPO antibody relates to thrombocytopenia and is rarely seen in hematopoietic and autoimmune diseases. To date, there had been no reports that focused on the anti-THPO antibody in patients with type 2 diabetes mellitus (T2DM). To evaluate prevalence of the anti-THPO antibody in patients with T2DM and the relationship between anti-THPO antibody and platelet count, a cross-sectional study was performed on 82 patients with T2DM. The anti-THPO antibody was measured by ELISA using preserved sera and detected in 13 patients. The average platelet count was significantly lower in patients with the anti-THPO antibody than in those without the anti-THPO antibody. Multivariate linear regression analyses showed a significant relationship between the anti-THPO antibody and platelet count, after adjusting for other variables. To our best knowledge, this was the first report on the effect of the anti-THPO antibody on platelet count in patients with T2DM. Further investigation is needed to validate the prevalence and pathological significance of the anti-THPO antibody in patients with T2DM.

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