scholarly journals Lipid profile abnormalities in newly diagnosed type 2 diabetics: a cross-sectional study

2019 ◽  
Vol 6 (5) ◽  
pp. 1452
Author(s):  
Monica A. ◽  
Dhivya P.

Background: India is fast becoming the diabetes capital of the World. A direct atherogenic effect of triglyceride rich particles has been noted. This study assesses the lipid profile abnormalities in newly diagnosed type 2 diabetes mellitus. Since dyslipidemia is a risk factor for cardiovascular disease, such assessment will enable better recognition, prevention and management of cardiovascular mortality and morbidity.Methods: The study was conducted over a period of one year at a tertiary care hospital in South India. A cross-sectional study of 100 newly diagnosed type 2 diabetics in a rural South-Indian population was done. Results: In our study, 55 (55%) participants had high triglycerides and 45 (45%) had normal triglycerides.  Among the 55 participants with abnormal triglycerides, 34% had borderline high levels (150-199mg/dl), 18% had high levels (200-499 mg/dl) and 3% participants had very high triglycerides (≥500 mg/dl). 26% male and 29% female participants had above normal triglyceride levels. In our study, 25% had borderline high cholesterol levels and 5% had high total Cholesterol. 39% of participants had near optimal levels of LDL, 19% had borderline high levels of LDL, 7% had high levels of LDL and 4% had very high levels of LDL. Significantly higher levels of triglycerides and LDL were noted.Conclusions: Deranged lipid profiles are quite prevalent in type 2 diabetics with females having higher triglyceride levels. Recognition of such elevated triglyceride levels in even newly diagnosed type 2 diabetics will help in better prevention of associated cardiovascular disease.

Author(s):  
Ashok Kumar ◽  
Naresh Kumar ◽  
Bhim Ram

Background: Diabetes is characterized by chronic hyperglycemia and disturbances of carbohydrate, lipid and protein metabolism. We aimed to research association between serum lipid profile and blood glucose, hypothesizing that early detection and treatment of lipid abnormalities can minimize the risk for atherogenic cardiovascular disorder and cerebrovascular accident in patients with type 2 diabetes mellitus. Material and methods: A cross-sectional study was carried out to determine the lipid profile levels in newly diagnosed type 2 diabetics in the Department of General Medicine in Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India from March 2019 to February 2020. A total of 200 newly diagnosed type 2 diabetics were enrolled in our study. Results: In our study, 96 (48.0%) participants had normal serum triglycerides levels which is <150 mg/dl whereas 104 (52.0%) participants had an abnormal level of serum triglycerides. Among the 104 (52.0%) participants with abnormal triglycerides, 30.5% had borderline high levels (150-199mg/dl), 19.5% had high levels (200-499 mg/dl) and 2% participants had very high triglycerides (≥500 mg/dl. In our study, among the 200 participants, 142 (71%) participants   had   desirable total   Cholesterol levels of <200mg/dl, 51 (25.5%) had borderline high levels of 200- 239mg/dl and 7 (3.5%) had high total cholesterol levels of ≥240mg/dl and 31% of participants had near optimal levels of LDL, 35.5% had borderline high levels of LDL, 12% had high levels of LDL and 1% had very high levels of LDL. Conclusions: Deranged lipid profiles are quite prevalent in type 2 diabetics with females having higher triglyceride levels. Recognition of such elevated triglyceride levels in even newly diagnosed type 2 diabetics will help in better prevention of associated cardiovascular disease. Keywords: Cardiovascular disease, Hypertriglyceridemia, Type 2 diabetes, Lipid profile


2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Yaa Obirikorang ◽  
Christian Obirikorang ◽  
Enoch Odame Anto ◽  
Emmanuel Acheampong ◽  
Nyalako Dzah ◽  
...  

This study aimed to determine the knowledge and prevalence of obesity among Ghanaian newly diagnosed type 2 diabetics. This cross-sectional study was conducted among diagnosed type 2 diabetics. Structured questionnaire was used to obtain data. Anthropometric measurements and fasting blood sugar levels were also assessed. Participants had adequate knowledge about the general concept of obesity (72.0%) and method of weight measurement (98.6%) but were less knowledgeable of ideal body weight (4.2%). The commonly known cause, complication, and management of obesity were poor diet (76.9%), hypertension (81.8%), and diet modification (86.7%), respectively. The anthropometric measures were higher among females compared to males. Prevalence of obesity was 61.3% according to WHR classification, 40.8% according to WHtR classification, 26.1% according to WC, and 14.8% according to BMI classification. Being female was significantly associated with high prevalence of obesity irrespective of the anthropometric measure used (p<0.05). Taking of snacks in meals, eating meals late at night, physical inactivity, excessive fast food intake, and alcoholic beverage intake were associated with increased prevalence of obesity (p<0.05). Prevalence of obesity is high among diabetic patient and thus increasing effort towards developing and making education programs by focusing on adjusting to lifestyle modifications is required.


2019 ◽  
Vol 69 (12) ◽  
pp. 3486-3489
Author(s):  
Gina Botnariu ◽  
Alina Popa ◽  
Geta Mitrea ◽  
Marius Manole ◽  
Mariana Pacurar ◽  
...  

Diabetes-related cognitive dysfunction is considered a long-term complication of diabetes. In this cross-sectional study was studied the relationship between cognitive dysfunction (assessed by using two standardized questionnaires), lipid profile parameters and fatty free acids intake, in outpatients, hospitalized for their periodical control. The Mini-Mental State Exam (MMSE) and The Montreal Cognitive Assessment (MoCA) score were related to the body mass index (BMI), high density cholesterol (HDLc), glycated hemoglobin (Hb A1c) and intake of choline and eicosapentaenoic acid (all Ps [ .05, excepting the relationship between MMSE and HDLc). The implications of FFA intake in dementia development, in type 2 diabetics, is important for disease management and prevention.


2021 ◽  
Author(s):  
Yanli Li ◽  
Min Yi ◽  
Xiaoyi Deng ◽  
Wangen Li ◽  
Yimei Chen ◽  
...  

Abstract Background Diabetes mellitus (DM) and thyroid dysfunction (TD) are two closely associated disorders. The coexistence of TD could adversely influence metabolic control and even increase the long-term mortality in patients with DM. The objective of the present study was to investigate the thyroid status and the relationship between thyroid hormones, diabetic complications and metabolic parameters in patients with newly diagnosed type 2 DM (T2DM). Methods This is an observational cross-sectional study, conducting on 340 patients with newly diagnosed T2DM who were admitted to ward of endocrinology department and 120 matched nondiabetic subjects. Clinical characteristics were collected and laboratory measurements were conducted. Results Levels of free T3 (FT3), free T4 (FT4) and TSH were significantly lower in patients with T2DM as compared to nondiabetic subjects. The prevalence of TD was 21.2% in patients with diabetes, higher than that of controls (4.2%). The low T3 syndrome was the most frequent TD, shown in 14.7% of patients. The presence of diabetic complications (diabetic nephropathy (DN), diabetic ketosis), metabolic and demographic factors, including age, glycemic control and insulin resistance were factors associated with levels of thyroid hormones. FT3 level was inversely correlated with the level of urinary total protein (mg/24h) and the presence of DN. Multivariate analysis indicated low FT3 level as a strong independent risk factor (OR = 0.364, P < 0.001) for DN. Conclusions TD is not rarely seen in patients with newly diagnosed T2DM. Diabetic complications and diabetes-related metabolic and demographic factors are related to TD. Decreased FT3 is strongly correlated with the presence of DN.


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