scholarly journals Preliminary study on the influencing factors of shear wave elastography for peripheral nerves in healthy population

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xinyi Tang ◽  
Bihui Zhu ◽  
Mei Tian ◽  
Ruiqian Guo ◽  
Songya Huang ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Median Nerve ◽  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Peripheral Nerves ◽  
Shear Wave Elastography ◽  
Healthy Population ◽  
Significant Difference ◽  
The Right

AbstractThis study took shear wave elastography (SWE) technology to measure the shear wave velocity (SWV) of peripheral nerve in healthy population, which represents the stiffness of the peripheral nerves, and research whether these parameters (location, age, sex, body mass index (BMI), the thickness and cross-sectional area(CSA) of the nerve) would affect the stiffness of the peripheral nerves. 105 healthy volunteers were enrolled in this study. We recorded the genders and ages of these volunteers, measured height and weight, calculated BMI, measured nerve thickness and CSA using high-frequency ultrasound (HFUS), and then, we measured and compared the SWV of the right median nerve at the middle of the forearm and at the proximal entrance of the carpal tunnel. The SWV of the median nerve of the left side was measured to explore whether there exist differences of SWV in bilateral median nerve. Additionally, we also measured the SWV of the right tibial nerve at the ankle canal to test whether there is any difference in shear wave velocity between different peripheral nerves. This study found that there existed significant differences of SWV between different sites in one nerve and between different peripheral nerves. No significant difference was found in SWV between bilateral median nerves. Additionally, the SWV of peripheral nerves was associated with gender, while not associated with age or BMI. The mean SWV of the studied male volunteers in median nerve were significantly higher than those of female (p < 0.05). Peripheral nerve SWE measurement in healthy people is affected by different sites, different nerves and genders, and not associated with age, BMI, nerve thickness or CSA.

scholarly journals Stiffness of the Masseter Muscle in Children—Establishing the Reference Values in the Pediatric Population Using Shear-Wave Elastography

2021 ◽  
Vol 18 (18) ◽  
pp. 9619
Author(s):  
Cyprian Olchowy ◽  
Anna Olchowy ◽  
Aleksander Pawluś ◽  
Mieszko Więckiewicz ◽  
Luca Maria Sconfienza
Keyword(s):  
Shear Wave ◽  
Masseter Muscle ◽  
Pediatric Population ◽  
Shear Wave Elastography ◽  
Total Sample ◽  
Healthy Children ◽  
Significant Difference ◽  
The Right ◽  
The Impact ◽  
Masseter Muscles

In children, the quality and muscle function are altered in many pathologic conditions, including temporomandibular disorders. Although several methods have been used to evaluate muscle tonus, none became a golden standard. Moreover, the masseter muscle characteristics in children have not been investigated to date. This study aimed to measure the stiffness of the masseter muscle using shear-wave elastography in healthy children. We enrolled 30 healthy children (mean age 10.87 ± 3.38 years). The stiffness of masseter muscles was measured with shear wave elastography. Stiffness for the total sample was 6.37 ± 0.77 kPa. A comparison of the measurements did not show significant differences between the right and the left masseter muscles (left—6.47 ± 0.78 kPa; right—6.24 ± 0.76 kPa; p = 0.3546). A significant difference was seen between boys and girls (boys—5.94 ± 0.50 kPa; girls—6.63 ± 0.80; p = 0.0006). Shear-wave elastography is a promising diagnostic tool. It may help to detect changes in the stiffness of the masseter muscle and draw attention to pathological processes within the jaw muscles. Directions for further research shall include determining stiffness values in pathological conditions and the impact of biological and functional factors on the stiffness of the masseter muscle.

scholarly journals Area Covered for Shear Wave Velocity Calculation Affects the Shear Wave Velocity Values

2019 ◽  
Vol 35 (3) ◽  
pp. 182-187
Author(s):  
Amitabh Dashottar ◽  
Erin Montambault ◽  
Jeffrey R. Betz ◽  
Kevin D. Evans
Keyword(s):  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Region Of Interest ◽  
Ultrasound Elastography ◽  
Maximum Area ◽  
Shear Wave Velocities ◽  
Significant Difference ◽  
Technical Specifications ◽  
The Mean

Although ultrasound elastography is established as a reliable and valid tool for assessment of skeletal muscles, guidelines around the technical specifications, data selection, and acquisition parameters still lack consensus. One such parameter is the use of the quantification box (Q-box) that calculates the shear wave velocity/modulus, within a selected region of interest (ROI). Currently, no data compare the effect of the elastographic area within the ROI to the mean shear wave velocity calculations, using a Q-box. In this study, the mean shear wave velocity calculated over a smaller (single Q-box) ROI is compared to the mean shear wave velocity calculated over maximum area of elastogram, within a ROI. Comparison of mean shear wave velocity revealed a significant difference ( t = 2.79, P = .007) between the means calculated over maximum area of elastogram for only nonuniform elastograms. The rater agreement for the classification scheme was assessed (κ = 0.85). To prevent possible overestimation of shear wave velocities, it may be necessary to place the Q-box over the maximum elastographic area.

scholarly journals Is shear wave elastography relevant in the diagnosis of polycystic ovarian syndrome?

2019 ◽  
Vol 21 (2) ◽  
pp. 158 ◽  
Author(s):  
Ersen Ertekin ◽  
Ozgür Deniz Turan ◽  
Ozum Tuncyurek
Keyword(s):  
Shear Wave ◽  
Polycystic Ovarian Syndrome ◽  
Imaging Finding ◽  
Shear Wave Elastography ◽  
Left Ovary ◽  
Control Group ◽  
Diagnostic Efficacy ◽  
Significant Difference ◽  
The Right ◽  
Ovarian Syndrome

Aim: The aim of this study was to determine the contribution of Shear Wave Elastography (SWE) to the diagnosis of polycystic ovarian syndrome (PCOS).Material and methods: Thirty-seven patients with PCOS diagnosis criteria were included in the study. Sixteen volunteer patients without hormonal disturbances and with normal menstrual cycles were evaluated as the control group. Gray scale ultrasonography (US) and SWE measurements in both ovaries were performed by a single radiologist who was blinded to the clinical and laboratory results.Results: The SWE measurements in PCOS group were 8.4±2.0 kPafor the right ovary and 9.4±3.9 kPa for the left ovary and in the control group 7.8±4.1 for the right ovary and 8.6±2.5 kPa for the left ovary. There was no statistically significant difference between the PCOS and the control group according to the SWE results (for right ovary p=0.356, for left ovary p=0.258, and total ovary p=0.293).Conclusions: The ovarian morphology isstill the most reliable imaging finding in the diagnosis of PCOS, although it is controversial especially among adolescents. Although the diagnostic efficacy of SWE is demonstrated in a variety of soft tissue lesions, we did not find any significant contribution of SWE to the diagnosis PCOS. Therefore, the promising value of elastography is yet to be defined for the diagnosis of PCOS.

No Association of Plantar Aponeurosis Stiffness with Medial Longitudinal Arch Stiffness

2021 ◽  
Author(s):  
Hiroaki Noro ◽  
Naokazu Miyamoto ◽  
Naotoshi Mitsukawa ◽  
Toshio Yanagiya
Keyword(s):  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Shear Wave Elastography ◽  
Medial Longitudinal Arch ◽  
Plantar Aponeurosis ◽  
Longitudinal Arch ◽  
The Difference ◽  
Young Subjects

AbstractLower stiffness of the medial longitudinal arch is reportedly a risk factor for lower leg disorders. The plantar aponeurosis is considered essential to maintaining the medial longitudinal arch. It is therefore expected that medial longitudinal arch stiffness is influenced by plantar aponeurosis stiffness. However, this has not been experimentally demonstrated. We examined the relationship between the plantar aponeurosis stiffness and medial longitudinal arch stiffness in humans in vivo. Thirty young subjects participated in this study. The navicular height and shear wave velocity (an index of stiffness) of the plantar aponeurosis were measured in supine and single-leg standing positions, using B-mode ultrasonography and shear wave elastography, respectively. The medial longitudinal arch stiffness was calculated based on body weight, foot length, and the difference in navicular height between the supine and single-leg standing conditions (i. e., navicular drop). Shear wave velocity of the plantar aponeurosis in the supine and single-leg standing positions was not significantly correlated to medial longitudinal arch stiffness (spine: r=−0.14, P=0.45 standing: r=−0.16, P=0.41). The findings suggest that the medial longitudinal arch stiffness would be strongly influenced by the stiffness of foot structures other than the plantar aponeurosis.

scholarly journals Shear Wave Ultrasonic Elastometry in Diagnostics of Metastatic Lymph Nodes in Neck Thyroid Cancer

2021 ◽  
Vol 4 (4) ◽  
pp. 50-55
Author(s):  
E. A. Gudilina ◽  
T. Yu. Danzanova ◽  
P. I. Lepedatu ◽  
G. T. Sinyukova
Keyword(s):  
Differential Diagnosis ◽  
Thyroid Cancer ◽  
Lymph Nodes ◽  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Soft Tissues ◽  
Statistical Significance ◽  
Metastatic Lesions ◽  
Significant Difference

Purpose: Determination of informative value of a new method of ultrasound tomography, based on the properties of elasticity of soft tissues, in the differential diagnosis of metastatic lesions of the lymph nodes of the neck thyroid cancer.Material and methods: To assess the capabilities of shear wave ultrasound elastometry in the diagnosis of metastatic lesions of the lymph nodes in thyroid cancer, a study was carried out with 45 patients with suspected thyroid cancer. The work was performed by devices Acuson S2000 Siemens, Avius hi vision Hitachi using a linear sensor with a frequency of 5–12 MHz. For each object of the study, from 5 to 10 measurements of the shear wave velocity in m / s were made, depending on the size of the lymph nodes.Results: Reliable results were obtained in the group of altered lymph nodes (statistical significance p < 0.05). Interquartile intervals and the most common values of shear wave velocities do not overlap: in metastases — 2.20– 3.36 m/s, with hyperplasia of lymph nodes — 0.70–1.88 m/s, and medians show a significant difference in velocities: metastases — 3.00 m/s, hyperplastic lymph nodes 1.38 m/s.Conclusions: Shear wave elastography objectifies ultrasound studies, obtaining specific indicators of shear wave velocity in the areas of interest, and can be used as an additional diagnostic tool in the differential diagnosis of metastatic and hyperplastic lymph nodes.

scholarly journals Эластографическая характеризация рака яичка (морфологические и технические аспекты)

2017 ◽  
pp. 25-39
Keyword(s):  
Testicular Cancer ◽  
Germ Cell ◽  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Germ Cell Tumors ◽  
Shear Wave Elastography ◽  
Ultrasound Elastography ◽  
Nonseminomatous Germ Cell Tumors ◽  
Multiparametric Ultrasound

Проведена ультразвуковая эластографическая оценка злокачественных опухолей яичка у 31 пациента в возрасте от 19 до 65 лет. Во всех случаях было одностороннее поражение. Во всех случаях диагноз подтвержден морфологически (семинома - 18 (58,1%), эмбриональная карцинома - 5 (16,1%), смешанные герминогенные опухоли - 7 (22,6%), спермоцитарная семинома - 1 (3,2%)). Пациенты были разделены на группы в зависимости от морфологических видов опухоли (семинома (n = 18) и несеминомные герминогенные опухоли (n = 12, в 2 случаях семинома была одним из компонентов смешанной герминогенной опухоли) (1 случай спермоцитарной семиномы был исключен из этой части анализа); тератома как компонент смешанной герминогенной опухоли (n = 6) и остальные герминогенные опухоли (n = 25)). Режим эластографии сдвиговой волной использовался после предварительной серошкальной визуализации яичек на аппаратах Aplio 500 (Toshiba, Япония) и Aixplorer (Supersonic Imagine, Франция) (линейные датчики 5-14 и 4-15 МГц соответственно). Технические аспекты: различия между измерениями значений модуля Юнга в опухолях яичка на аппарате (1) Aplio 500 и аппарате (2) Aixplorer недостоверны (P = 0,95). Корреляция между значениями модуля Юнга, полученными на двух приборах, высокая (rs = 0,86, P = 0,0137). Значения модуля Юнга в опухолях яичка достоверно выше по сравнению с эхографически неизмененной паренхимой ипсилатерального яичка (P = 0,0017 для указанных сравнений на двух аппаратах) и паренхимой эхографически неизмененного контрлатерального яичка (P = 0,0017 для указанных сравнений на двух аппаратах) на фоне отсутствия достоверности различий между значениями модуля Юнга в двух яичках (неизмененные участки ипсилатерального яичка и паренхима среднего сегмента контрлатерального яичка) (P = 0,4057 и P = 0,8480 для аппаратов 1 и 2 соответственно). Морфологические аспекты (аппарат Aixplorer): медиана Emean в группе семиномы (n = 18) составила 110,3 кПа, 25-75-й процентили - 77,6-159,0 кПа, 5-95-й процентили - 16.5- 222,1 кПа, минимальное - максимальное значения - 15,3-241,4 кПа; в группе несеминомных герминогенных опухолей (n = 12) - 109,9 кПа, 83,0-129,0 кПа, 55.5- 156,8 кПа, 54,2-157,8 кПа (различия недостоверны при P=0,9325). Отсутствие достоверности различий также было определено при сравнении смешанных герминогенных опухолей, в составе которых была тератома, и остальных опухолей (P = 0,5823). Различия значений индексов жесткости (индекс жесткости 1 - отношение значений Emean в областях опухоли и эхографически неизмененной паренхимы ипсилатерального яичка, индекс жесткости 2 - отношение значений Emean в областях опухоли и паренхимы эхографически неизмененного контрлатерального яичка, индекс жесткости 3 - внутриопухолевый индекс жесткости с учетом участков с максимальной и минимальной жесткостью внутри объемного образования) у пациентов с семиномами и несеминомными герминогенными опухолями не выявлены. Ключевые слова: мультипараметрическая ультразвуковая диагностика, ультразвуковая эластография, эластография сдвиговой волной, жесткость, модуль Юнга, скорость сдвиговой волны, рак яичка, семинома, несеминомные герминогенные опухоли, multiparametric ultrasound, ultrasound elastography, shear wave elastography, stiffness, Young’s modulus, shear wave velocity, testicular cancer, seminoma, nonseminomatous germ cell tumors

scholarly journals Parameter Identification for Ultrasound Shear Wave Elastography Simulation

2021 ◽  
Vol 7 (1) ◽  
pp. 35-38
Author(s):  
M. Neidhardt ◽  
J. Ohlsen ◽  
N. Hoffmann ◽  
A. Schlaefer
Keyword(s):  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Shear Wave Elastography ◽  
Material Model ◽  
Percentage Error ◽  
Tissue Elasticity ◽  
Phantom Experiment ◽  
Tissue Phantom ◽  
Wave Imaging

Abstract Elasticity of soft tissue is a valuable information to physicians in treatment and diagnosis of diseases. The elastic properties of tissue can be estimated with ultrasound (US) shear wave imaging (SWEI). In US-SWEI, a force push is applied inside the tissue and the resulting shear wave is detected by high-frequency imaging. The properties of the wave such as the shear wave velocity can be mapped to tissue elasticity. Commonly, wave features are extracted by tracking the peak of the shear wave, estimating the phase velocity or with machine learning methods. To tune and test these methods, often simulation data is employed since material properties and excitation can be accurately controlled. Subsequent validation on real US-SWEI data is in many cases performed on tissue phantoms such as gelatine. Clearly, validation performance of these procedures is dependent on the accuracy of the simulated tissue phantom and a thorough comparison of simulation and experimental data is needed. In this work, we estimate wave parameters from 400 US-SWEI data sets acquired in various homogeneous gelatine phantoms. We tune a linear material model to these parameters. We report an absolute percentage error for the shear wave velocity between simulation and phantom experiment of <2.5%. We validate our material model on unknown gelatine concentrations and estimate the shear wave velocity with an error <3.4% for in-range concentrations indicating that our material model is in good agreement with US-SWEI measurements.

scholarly journals Ultrasound shear wave elastography of the anterior talofibular and calcaneofibular ligaments in healthy subjects

2021 ◽  
Vol 21 (85) ◽  
pp. e86-e94
Author(s):  
Lana H Gimber ◽  
◽  
L. Daniel Latt ◽  
Chelsea Caruso ◽  
Andres A. Nuncio Zuniga ◽  
...  
Keyword(s):  
Shear Wave ◽  
Wave Velocity ◽  
Shear Wave Velocity ◽  
Shear Wave Elastography ◽  
Observer Agreement ◽  
Anterior Talofibular Ligament ◽  
Calcaneofibular Ligament ◽  
Ankle Ligaments ◽  
Lateral Ankle ◽  
Lateral Ankle Ligaments

Aim of study: Most sprained lateral ankle ligaments heal uneventfully, but in some cases the ligament’s elastic function is not restored, leading to chronic ankle instability. Ultrasound shear wave elastography can be used to quantify the elasticity of musculoskeletal soft tissues; it may serve as a test of ankle ligament function during healing to potentially help differentiate normal from ineffective healing. The purpose of this study was to determine baseline shear wave velocity values for the lateral ankle ligaments in healthy male subjects, and to assess inter-observer reliability. Material and methods: Forty-six ankles in 23 healthy male subjects aged 20–40 years underwent shear wave elastography of the lateral ankle ligaments performed by two musculoskeletal radiologists. Each ligament was evaluated three times with the ankle relaxed by both examiners, and under stress by a single examiner. Mean shear wave velocity values were compared for each ligament by each examiner. Inter-observer agreement was evaluated. Results: The mean shear wave velocity at rest for the anterior talofibular ligament was 2.09 ± 0.3 (range 1.41–3.17); and for the calcaneofibular ligament 1.99 ± 0.36 (range 1.29–2.88). Good inter-observer agreement was found for the anterior talofibular ligament and calcaneofibular ligament shear wave velocity measurements with the ankle in resting position. There was a significant difference in mean shear wave velocities between rest and stressed conditions for both anterior talofibular ligament (2.09 m/s vs 3.21 m/s; p <0.001) and calcaneofibular ligament (1.99 m/s vs 3.42 m/s; p <0.0001). Conclusion: Shear wave elastography shows promise as a reproducible method to quantify ankle ligament stiffness. This study reveals that shear waves velocities of the normal lateral ankle ligaments increased with applied stress compared to the resting state.

A case of lung cancer and a case of pneumonia adjacent to the pleura in which shear wave velocity could be measured by shear wave elastography from the body surface

Choonpa Igaku ◽  
2018 ◽  
Vol 45 (4) ◽  
pp. 439-443
Author(s):  
Naoki HAMAZAKI ◽  
Naohisa SHIOYA ◽  
Teruhiko IMAI ◽  
Kouji HAYASHIDA ◽  
Motoaki YASUKAWA ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Shear Wave ◽  
Wave Velocity ◽  
Body Surface ◽  
Shear Wave Velocity ◽  
Shear Wave Elastography ◽  
The Body
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