Anti-inflammatory activity and molecular mechanism of Oolong tea theasinensin

2014 ◽  
Vol 5 (8) ◽  
pp. 1891-1897 ◽  
Author(s):  
Ayami Hisanaga ◽  
Hisako Ishida ◽  
Kozue Sakao ◽  
Takayuki Sogo ◽  
Takuma Kumamoto ◽  
...  
Keyword(s):  
Molecular Mechanism ◽  
Green Tea ◽  
Bioactive Compounds ◽  
Black Tea ◽  
Tea Polyphenols ◽  
Inflammatory Activity ◽  
Tea Catechins ◽  
Oolong Tea ◽  
Green Tea Catechins ◽  
Anti Inflammatory

Oolong tea theasinensins are a group of tea polyphenols different from green tea catechins and black tea theaflavins, and they are considered as bioactive compounds in oolong tea.

scholarly journals Beneficial Properties of Green Tea Catechins

2020 ◽  
Vol 21 (5) ◽  
pp. 1744 ◽  
Author(s):  
Claudia Musial ◽  
Alicja Kuban-Jankowska ◽  
Magdalena Gorska-Ponikowska
Keyword(s):  
Green Tea ◽  
Antioxidant Properties ◽  
Biologically Active ◽  
Hydroxyl Groups ◽  
Molecular Signaling ◽  
Epicatechin Gallate ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Antioxidant Agents ◽  
Anti Inflammatory

Green tea (Camellia sinesis) is widely known for its anticancer and anti-inflammatory properties. Among the biologically active compounds contained in Camellia sinesis, the main antioxidant agents are catechins. Recent scientific research indicates that the number of hydroxyl groups and the presence of characteristic structural groups have a major impact on the antioxidant activity of catechins. The best source of these compounds is unfermented green tea. Depending on the type and origin of green tea leaves, their antioxidant properties may be uneven. Catechins exhibit the strong property of neutralizing reactive oxygen and nitrogen species. The group of green tea catechin derivatives includes: epicatechin, epigallocatechin, epicatechin gallate and epigallocatechin gallate. The last of these presents the most potent anti-inflammatory and anticancer potential. Notably, green tea catechins are widely described to be efficient in the prevention of lung cancer, breast cancer, esophageal cancer, stomach cancer, liver cancer and prostate cancer. The current review aims to summarize the potential anticancer effects and molecular signaling pathways of major green tea catechins. It needs to be clearly emphasized that green tea as well as green tea catechols cannot replace the standard chemotherapy. Nonetheless, their beneficial effects may support the standard anticancer approach.

scholarly journals Green Tea, Black Tea, and Oolong Tea Polyphenols Reduce Visceral Fat and Inflammation in Mice Fed High-Fat, High-Sucrose Obesogenic Diets

2014 ◽  
Vol 144 (9) ◽  
pp. 1385-1393 ◽  
Author(s):  
David Heber ◽  
Yanjun Zhang ◽  
Jieping Yang ◽  
Janice E. Ma ◽  
Susanne M. Henning ◽  
...  
Keyword(s):  
Green Tea ◽  
Visceral Fat ◽  
Black Tea ◽  
Tea Polyphenols ◽  
High Fat ◽  
Oolong Tea ◽  
High Sucrose

scholarly journals Review: Telaah Kandungan Senyawa Katekin dan Epigalokatekin Galat (EGCG) sebagai Antioksidan pada Berbagai Jenis Teh

2021 ◽  
Vol 8 (1) ◽  
pp. 31
Author(s):  
Zahra Hasna Fadhilah ◽  
Farid Perdana ◽  
Raden Aldizal Mahendra Rizkio Syamsudin
Keyword(s):  
Antioxidant Activity ◽  
Green Tea ◽  
Bioactive Compounds ◽  
Bitter Taste ◽  
Epigallocatechin Gallate ◽  
Black Tea ◽  
Major Determinant ◽  
Oolong Tea ◽  
Ic50 Value ◽  
High Antioxidant Activity

Katekin merupakan senyawa bioaktif dengan kerangka flavan-3-ol dan menjadi senyawa utama penentu mutu serta dapat memberikan rasa pahit yang khas pada teh. Senyawa turunan katekin yang memiliki aktivitas sebagai antioksidan paling kuat dan melimpah yaitu epigalokatekin galat. Tujuan dari review artikel ini yaitu untuk mengetahui kandungan senyawa katekin dan epigalokatekin galat sebagai antioksidan pada berbagai jenis teh berdasarkan nilai IC50.Metode penulisan review artikel ini dilakukan dengan mencari serta menganalisis studi pustaka dari beberapa jurnal yang berkaitan dengan aktivitas antioksidan pada berbagai jenis teh dengan penelusuran terhadap senyawa katekin, khususnya epigalokatekin galat. Hasil review menunjukkan bahwa aktivitas antioksidan pada pengolahan jenis teh seperti teh hijau, teh oolong, dan teh hitam memiliki perbedaan yang cukup signifikan yang dapat dilihat dari kandungan senyawa katekin dan EGCG dimana semakin besar kandungan senyawa tersebut, maka aktivitas antioksidannya semakin tinggi. Selain itu, tingginya aktivitas antioksidan dapat dilihat dari nilai IC50. Semakin rendah nilai IC50, maka aktifitas antioksidan akan semakin tinggi. Teh hijau terbukti memiliki aktivitas antioksidan yang paling tinggi diantara teh lainnya dengan kandungan katekin sebesar 10,04% dan epigalokatekin galat sebesar 3,28% serta nilai IC50 yang paling rendah yaitu 58,61 µg/mL. Kata Kunci: Katekin, Teh Hijau, Teh Oolong, Teh Hitam, Antioksidan Catechins are bioactive compounds with a flavan-3-ol structure and become a major determinant of quality compounds and can give a distinctive bitter taste of tea. Catechin derivative compounds that have the antioxidant activity as the strongest and abundant are epigallocatechin gallate. The purpose of this article review was to determine the content of catechins and epigallocatechin gallate compounds as an antioxidant in various types of tea based on the IC50 value. The method of writing of this article review was carried out by searching and analyzing literature studies from several journals related to antioxidant activity in various types of tea by tracing catechin compounds, especially the epigallocatechin gallate. The results of the review showed that the antioxidant activity in the processing of types of tea such as green tea, oolong tea, and black tea has significant differences which could be seen from the content of catechins and EGCG compounds where the greater the content of the compounds, the higher the antioxidant activity. Also, the high antioxidant activity can be seen from the IC50 value. The lower the IC50 value, the higher the antioxidant activity. Green tea shows to have the highest antioxidant activity among other teas with a catechin content of 10.04% and an epigallocatechin gallate of 3.28% and the lowest IC50 value of 58.61 µg/mL.

Green Tea Catechins Improve Liver Dysfunction Following Massive Hepatectomy Through Anti-Oxidative and Anti-Inflammatory Activities in Rats

2011 ◽  
Vol 140 (5) ◽  
pp. S-928 ◽  
Author(s):  
Yu Saito ◽  
Mitsuo Shimada ◽  
Tohru Utsunomiya ◽  
Satoru Imura ◽  
Yuji Morine ◽  
...  
Keyword(s):  
Green Tea ◽  
Liver Dysfunction ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Massive Hepatectomy ◽  
Anti Inflammatory

scholarly journals Green Tea Catechins Improve Human Forearm Vascular Function and Have Potent Anti-Inflammatory and Anti-Apoptotic Effects in Smokers

2010 ◽  
Vol 49 (23) ◽  
pp. 2553-2559 ◽  
Author(s):  
Jun-ichi Oyama ◽  
Toyoki Maeda ◽  
Makoto Sasaki ◽  
Kazuya Kozuma ◽  
Ryuji Ochiai ◽  
...  
Keyword(s):  
Green Tea ◽  
Vascular Function ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Human Forearm ◽  
Anti Inflammatory ◽  
Apoptotic Effects
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