A “turn-on” silver nanocluster based fluorescent sensor for folate receptor detection and cancer cell imaging under visual analysis

2015 ◽  
Vol 51 (59) ◽  
pp. 11810-11813 ◽  
Author(s):  
Hong Jiang ◽  
Gang Xu ◽  
Yimin Sun ◽  
Weiwei Zheng ◽  
Xiangxiang Zhu ◽  
...  

A novel terminal protection based label-free and “turn-on” fluorescent sensor for detection of folate receptors (FRs) and HeLa cells is developed by fluorescence resonance energy transfer (FRET) between single-walled carbon nanotubes (SWCNTs) and silver nanoclusters (AgNCs).

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.


2020 ◽  
Vol 21 (14) ◽  
pp. 5004
Author(s):  
Ekaterina O. Serebrovskaya ◽  
Nadezda M. Podvalnaya ◽  
Varvara V. Dudenkova ◽  
Anna S. Efremova ◽  
Nadya G. Gurskaya ◽  
...  

Poly-(ADP-ribosyl)-ation (PARylation) is a reversible post-translational modification of proteins and DNA that plays an important role in various cellular processes such as DNA damage response, replication, transcription, and cell death. Here we designed a fully genetically encoded fluorescent sensor for poly-(ADP-ribose) (PAR) based on Förster resonance energy transfer (FRET). The WWE domain, which recognizes iso-ADP-ribose internal PAR-specific structural unit, was used as a PAR-targeting module. The sensor consisted of cyan Turquoise2 and yellow Venus fluorescent proteins, each in fusion with the WWE domain of RNF146 E3 ubiquitin ligase protein. This bipartite sensor named sPARroW (sensor for PAR relying on WWE) enabled monitoring of PAR accumulation and depletion in live mammalian cells in response to different stimuli, namely hydrogen peroxide treatment, UV irradiation and hyperthermia.


2019 ◽  
Vol 43 (33) ◽  
pp. 13143-13151 ◽  
Author(s):  
Shimeng Liu ◽  
Changyin Lv ◽  
Ran Liu ◽  
Guiying Yang ◽  
Shiya Li ◽  
...  

The principle of sensitive detection of glucose in human serum using Bro-AuNCs @MnO2 nanocomposites as a fluorescent sensor.


2019 ◽  
Vol 43 (23) ◽  
pp. 9226-9231
Author(s):  
Yuling Fu ◽  
Wenjing Qi ◽  
Hongkun He ◽  
Maoyu Zhao ◽  
Di Wu ◽  
...  

The ECL donor Ru(bpy)32+-doped silica nanoparticles and acceptor methylene blue were applied in the electrochemiluminescence resonance energy transfer-based detection of glucose.


The Analyst ◽  
2020 ◽  
Vol 145 (22) ◽  
pp. 7412-7420
Author(s):  
Hui Liu ◽  
Hao Yin ◽  
TingTing Yang ◽  
HouCheng Ding ◽  
YongPing Dong

A label-free ECL sensor for thrombin was fabricated based on ECL resonance energy transfer occurred between ZnGa2O4/g-C3N4 and AuNP/GR nanocomposites, which revealed a new role of spinel-type semiconductor oxides in the fabrication of ECL sensors.


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