Ultrafast and nonlinear surface-enhanced Raman spectroscopy

2016 ◽  
Vol 45 (8) ◽  
pp. 2263-2290 ◽  
Author(s):  
Natalie L. Gruenke ◽  
M. Fernanda Cardinal ◽  
Michael O. McAnally ◽  
Renee R. Frontiera ◽  
George C. Schatz ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Future Directions ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Nonlinear Surface

This review discusses the origins, latest advances, challenges, and future directions of the emerging field of ultrafast surface-enhanced Raman spectroscopy.

Surface-enhanced Raman spectroscopy: bottlenecks and future directions

2018 ◽  
Vol 54 (1) ◽  
pp. 10-25 ◽  
Author(s):  
Rajapandiyan Panneerselvam ◽  
Guo-Kun Liu ◽  
Yao-Hui Wang ◽  
Jun-Yang Liu ◽  
Song-Yuan Ding ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Future Perspectives ◽  
Future Directions ◽  
Feature Article ◽  
The Past ◽  
Early Stages ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This feature article discusses developmental bottleneck issues in surface Raman spectroscopy in its early stages and surface-enhanced Raman spectroscopy (SERS) in the past four decades and future perspectives.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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