Coumarin-containing-star-shaped 4-arm-polyethylene glycol: targeted fluorescent organic nanoparticles for dual treatment of photodynamic therapy and chemotherapy

2015 ◽  
Vol 14 (7) ◽  
pp. 1329-1336 ◽  
Author(s):  
Moumita Gangopadhyay ◽  
Tanya Singh ◽  
Krishna Kalyani Behara ◽  
S. Karwa ◽  
S. K. Ghosh ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Polyethylene Glycol ◽  
Polymeric Nanoparticles ◽  
Single Component ◽  
Organic Nanoparticles ◽  
Fluorescent Organic Nanoparticles ◽  
Dual Treatment

Single-component targeted fluorescent organic polymeric nanoparticles are synthesized from star-shaped 4-arm-PEG containing coumarin for concomitant photodynamic and chemotherapy to efficiently annihilate tumour.

Single-Component Fluorescent Organic Nanoparticles with Four-Armed Phototriggers for Chemo-Photodynamic Therapy and Cellular Imaging

2019 ◽  
Vol 2 (6) ◽  
pp. 3728-3734 ◽  
Author(s):  
C. Parthiban ◽  
Pavithra M. ◽  
L. Vinod Kumar Reddy ◽  
Dwaipayan Sen ◽  
N. D. Pradeep Singh
Keyword(s):  
Photodynamic Therapy ◽  
Cellular Imaging ◽  
Single Component ◽  
Organic Nanoparticles ◽  
Fluorescent Organic Nanoparticles

Exploration of dynamic self-assembly mediated nanoparticle formation using perylenemonoimide–pyrene conjugate: a tool towards single-component white-light emission

2018 ◽  
Vol 6 (42) ◽  
pp. 11328-11335 ◽  
Author(s):  
Nilotpal Kapuria ◽  
Vikas Sharma ◽  
Prashant Kumar ◽  
Apurba Lal Koner
Keyword(s):  
White Light ◽  
Self Assembly ◽  
Light Emission ◽  
Cost Effective ◽  
White Light Emission ◽  
Single Component ◽  
Organic Nanoparticles ◽  
Nanoparticle Formation ◽  
Fluorescent Organic Nanoparticles

The formulation of fluorescent organic nanoparticles in an easy and cost-effective way is the desideratum.

Visible-Light -Triggered Fluorescent Organic Nanoparticles for Chemo-Photodynamic Therapy with Real-Time Cellular Imaging

2018 ◽  
Vol 1 (11) ◽  
pp. 6281-6288 ◽  
Author(s):  
C. Parthiban ◽  
Pavithra M. ◽  
Vinod Kumar Reddy L. ◽  
Dwaipayan Sen ◽  
Melvin Samuel S. ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Visible Light ◽  
Real Time ◽  
Cellular Imaging ◽  
Organic Nanoparticles ◽  
Fluorescent Organic Nanoparticles

Photocontrolled Nuclear-Targeted Drug Delivery by Single Component Photoresponsive Fluorescent Organic Nanoparticles of Acridin-9-Methanol

2013 ◽  
Vol 24 (11) ◽  
pp. 1828-1839 ◽  
Author(s):  
Avijit Jana ◽  
Biswajit Saha ◽  
Deb Ranjan Banerjee ◽  
Sudip Kumar Ghosh ◽  
Kim Truc Nguyen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Single Component ◽  
Organic Nanoparticles ◽  
Fluorescent Organic Nanoparticles ◽  
Targeted Drug

A new route towards fluorescent organic nanoparticles with red-shifted emission and increased colloidal stability

Tetrahedron ◽  
2014 ◽  
Vol 70 (10) ◽  
pp. 1903-1909 ◽  
Author(s):  
Kassem Amro ◽  
Jonathan Daniel ◽  
Guillaume Clermont ◽  
Talia Bsaibess ◽  
Mathieu Pucheault ◽  
...  
Keyword(s):  
Colloidal Stability ◽  
Organic Nanoparticles ◽  
Fluorescent Organic Nanoparticles

Current phthalocyanines delivery systems in photodynamic therapy: an updated review

2021 ◽  
Vol 28 ◽  
Author(s):  
Mariana Miretti ◽  
Cesar German Prucca ◽  
Tomas Cristian Tempesti ◽  
Maria Teresa Baumgartner
Keyword(s):  
Photodynamic Therapy ◽  
Polymeric Micelles ◽  
Polymeric Nanoparticles ◽  
Aqueous Media ◽  
Delivery Systems ◽  
Current Status ◽  
Oxygen Species ◽  
Cancer Treatments ◽  
Therapy Efficacy ◽  
Cellular Components

: Photodynamic therapy has emerged as an effective therapeutic alternative to treat oncological, cardiovascular, dermatological, infectious, and ophthalmic diseases. Photodynamic therapy combines the action of a photosensitizer with light in the presence of oxygen to generate reactive oxygen species capable of reacting with cellular components resulting in injury and, consequently, inducing cellular death. Phthalocyanines are considered good photosensitizers, although most of them are lipophilic, difficulting their administration for clinical use. A strategy to overcome the lack of solubility of phthalocyanines in aqueous media is to incorporate them into different delivery systems. The present review aimed to summarize the current status of the main drug delivery systems used for Zn and Al phthalocyanines and their effect in photodynamic therapy, reported in the last five years. Liposomes, polymeric micelles, polymeric nanoparticles, and gold-nanoparticles constituted some of the most used carriers and were discussed in this review. The latest studies reported strongly suggests that the application of nanotechnologies as delivery systems allow an increase in photodynamic therapy efficacy and reduce side-effects associated with the phthalocyanine administration, which represents a promise for cancer treatments.

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