Coaxial nanotubes of stimuli responsive polymers with tunable release kinetics

Soft Matter ◽  
2015 ◽  
Vol 11 (41) ◽  
pp. 8069-8075 ◽  
Author(s):  
Efe Armagan ◽  
Gozde Ozaydin Ince
Keyword(s):  
Release Kinetics ◽  
Polymer Chemistry ◽  
Stimuli Responsive ◽  
Release Rates ◽  
Polymer Layers ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Responsive Polymer ◽  
Tunable Release ◽  
Stimuli Responsive Polymer

Coaxial nanotubes with different stimuli responsive polymer layers demonstrate triggered response with release rates that can be controlled by tuning the polymer chemistry.

Stimuli-responsive polymer-based systems for diagnostic applications

2020 ◽  
Vol 8 (32) ◽  
pp. 7042-7061 ◽  
Author(s):  
Tong Shu ◽  
Liang Hu ◽  
Qiming Shen ◽  
Li Jiang ◽  
Qiang Zhang ◽  
...  
Keyword(s):  
Molecular Diagnostics ◽  
Stimuli Responsive ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Responsive Polymer ◽  
Diagnostic Applications ◽  
Stimuli Responsive Polymer

The unique properties of stimuli-responsive polymers make them valuable for myriad applications, their use for biosensing and molecular diagnostics is reviewed here.

Stimuli-Responsive Polymers with Tunable Release Kinetics

2020 ◽  
pp. 65-123
Author(s):  
Mehmet Can Zeybek ◽  
Egemen Acar ◽  
Gozde Ozaydin-Ince
Keyword(s):  
Release Kinetics ◽  
Stimuli Responsive ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Tunable Release

scholarly journals Stimuli-responsive polymers and their applications

2017 ◽  
Vol 8 (1) ◽  
pp. 127-143 ◽  
Author(s):  
Menglian Wei ◽  
Yongfeng Gao ◽  
Xue Li ◽  
Michael J. Serpe
Keyword(s):  
Drug Delivery ◽  
Physical Properties ◽  
Artificial Muscles ◽  
Stimuli Responsive ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Responsive Polymer ◽  
External Stimuli

Responsive polymer-based materials are capable of altering their chemical and/or physical properties upon exposure to external stimuli. This review highlights their use for sensing and biosensing, drug delivery, and artificial muscles/actuators.

Stimuli-responsive polymer layers for advanced cell culture technologies

2007 ◽  
Vol 98 (7) ◽  
pp. 646-650 ◽  
Author(s):  
Brigitte Voit ◽  
Dirk Schmaljohann ◽  
Stefan Gramm ◽  
Mirko Nitschke ◽  
Carsten Werner
Keyword(s):  
Cell Culture ◽  
Stimuli Responsive ◽  
Polymer Layers ◽  
Responsive Polymer ◽  
Stimuli Responsive Polymer

scholarly journals Stimuli-Responsive Polymers for Transdermal, Transmucosal and Ocular Drug Delivery

Pharmaceutics ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2050
Author(s):  
Dmitriy Berillo ◽  
Zharylkasyn Zharkinbekov ◽  
Yevgeniy Kim ◽  
Kamila Raziyeva ◽  
Kamila Temirkhanova ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Release Kinetics ◽  
Primary Metabolism ◽  
Stimuli Responsive ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Diffusion Parameters ◽  
Routes Of Drug Administration ◽  
Alternative Routes ◽  
Multiple Drugs

Despite their conventional and widespread use, oral and intravenous routes of drug administration face several limitations. In particular, orally administered drugs undergo enzymatic degradation in the gastrointestinal tract and first-pass metabolism in the liver, which tend to decrease their bioavailability. Intravenous infusions of medications are invasive, painful and stressful for patients and carry the risk of infections, tissue damage and other adverse reactions. In order to account for these disadvantages, alternative routes of drug delivery, such as transdermal, nasal, oromucosal, ocular and others, have been considered. Moreover, drug formulations have been modified in order to improve their storage stability, solubility, absorption and safety. Recently, stimuli-responsive polymers have been shown to achieve controlled release and enhance the bioavailability of multiple drugs. In this review, we discuss the most up-to-date use of stimuli-responsive materials in order to optimize the delivery of medications that are unstable to pH or undergo primary metabolism via transdermal, nasal, oromucosal and ocular routes. Release kinetics, diffusion parameters and permeation rate of the drug via the mucosa or skin are discussed as well.

Fast and Spatially Resolved Environmental Probing Using Stimuli-Responsive Polymer Layers and Fluorescent Nanocrystals

2006 ◽  
Vol 18 (11) ◽  
pp. 1453-1457 ◽  
Author(s):  
L. Ionov ◽  
S. Sapra ◽  
A. Synytska ◽  
A. L. Rogach ◽  
M. Stamm ◽  
...  
Keyword(s):  
Stimuli Responsive ◽  
Polymer Layers ◽  
Spatially Resolved ◽  
Responsive Polymer ◽  
Stimuli Responsive Polymer

scholarly journals Selected Applications of Stimuli-Responsive Polymers: 4D Printing by the Fused Filament Fabrication Technology

2020 ◽  
Vol 31 ◽  
pp. 13-22
Author(s):  
Y. Ahroni ◽  
N. Dresler ◽  
A. Ulanov ◽  
D. Ashkenazi ◽  
M. Aviv ◽  
...  
Keyword(s):  
Colour Change ◽  
Stimuli Responsive ◽  
4D Printing ◽  
Fused Filament Fabrication ◽  
Responsive Materials ◽  
Temperature Changes ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymer ◽  
Colour Changes ◽  
Stimuli Responsive Polymer

In the past few years four-dimensional (4D) printing technologies have attained worldwide interest and they are now considered the "next big thing". The aim of this research is to provide three selected examples of stimuli-responsive polymer (SRP) applications additively manufactured (AM) by the fused filament fabrication (FFF) technique. To that end, a CCT BLUE filament of thermo-responsive polymer was chosen to produce a water temperature indicator, which changes colour from blue to white when temperature increases; a CCU RED filament of photo-responsive polymer was used to produce a sunlight / UV indicator bracelet; a transparent PLA CLEAR polymer, a CCU RED photo-responsive polymer, and an electrical conductive PLA polymer were selected to produce a smart business card stand. The temperature indicator capability was analysed based on examining colour changes as a function of temperature changes. The sunlight/UV indicator capability was analysed based on the inspection of colour change as a function of absorbed sun/ultraviolet light. The electrical conductivity of the conductive PLA polymer was examined by performing resistance measurements. All three objects were successfully produced and their functionality was demonstrated. We hope that these examples will catalyse the expansion of FFF 4D printed SRP applications, as much work remains to be done in designing the parts and developing FFF printing parameters that take advantage of the stimuli-responsive materials currently being developed for FFF technology.

Amino-functional polyethers: versatile, stimuli-responsive polymers

2020 ◽  
Vol 11 (24) ◽  
pp. 3940-3950 ◽  
Author(s):  
Patrick Verkoyen ◽  
Holger Frey
Keyword(s):  
Ring Opening ◽  
Review Article ◽  
Stimuli Responsive ◽  
New Class ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers

Amino-functional polyethers have emerged as a new class of “smart”, i.e. pH- and thermoresponsive materials. This review article summarizes the synthesis and applications of these materials, obtained from ring-opening of suitable epoxide monomers.

Smart Drug Release Systems Based on Stimuli-Responsive Polymers

2013 ◽  
Vol 13 (9) ◽  
pp. 1369-1380 ◽  
Author(s):  
Guangyan Qing ◽  
Minmin Li ◽  
Lijing Deng ◽  
Ziyu Lv ◽  
Peng Ding ◽  
...  
Keyword(s):  
Drug Release ◽  
Stimuli Responsive ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Smart Drug

scholarly journals Thermo- and Photoresponsive Behaviors of Dual-Stimuli-Responsive Organogels Consisting of Homopolymers of Coumarin-Containing Methacrylate

Polymers ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 329
Author(s):  
Seidai Okada ◽  
Eriko Sato
Keyword(s):  
Functional Group ◽  
Solution Temperature ◽  
Stimuli Responsive ◽  
Critical Solution Temperature ◽  
Equilibrium Degree ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers ◽  
Dual Functional ◽  
Wide Range ◽  
Increasing Temperature

Coumarin-containing vinyl homopolymers, such as poly(7-methacryloyloxycoumarin) (P1a) and poly(7-(2′-methacryloyloxyethoxy)coumarin) (P1b), show a lower critical solution temperature (LCST) in chloroform, which can be controlled by the [2 + 2] photochemical cycloaddition of the coumarin moiety, and they are recognized as monofunctional dual-stimuli-responsive polymers. A single functional group of monofunctional dual-stimuli-responsive polymers responds to dual stimuli and can be introduced more uniformly and densely than those of dual-functional dual-stimuli-responsive polymers. In this study, considering a wide range of applications, organogels consisting of P1a and P1b, i.e., P1a-gel and P1b-gel, respectively, were synthesized, and their thermo- and photoresponsive behaviors in chloroform were investigated in detail. P1a-gel and P1b-gel in a swollen state (transparent) exhibited phase separation (turbid) through a temperature jump and reached a shrunken state (transparent), i.e., an equilibrium state, over time. Moreover, the equilibrium degree of swelling decreased non-linearly with increasing temperature. Furthermore, different thermoresponsive sites were photopatterned on the organogel through the photodimerization of the coumarin unit. The organogels consisting of homopolymers of coumarin-containing methacrylate exhibited unique thermo- and photoresponsivities and behaved as monofunctional dual-stimuli-responsive organogels.

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