An ultrasensitive nanobiohybrid platform for glucose electrochemical biosensing based on ferrocenyl iminopropyl-modified silica nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (52) ◽  
pp. 46238-46243 ◽  
Author(s):  
M. Saadaoui ◽  
M. Braiek ◽  
N. Jaffrezic-Renault ◽  
N. Raouafi

A novel nanobiohybrid platform based on ferrocenyl iminopropyl-modified silica nanoparticle conjugates (fap-SiNPs), entrapped in glucose oxidase (GOx) and bovine serum albumin cross-linked with glutaraldehyde, was developed.

2020 ◽  
Vol 186 ◽  
pp. 110677 ◽  
Author(s):  
Flávia Elisa Galdino ◽  
Agustin Silvio Picco ◽  
Maurício Luis Sforca ◽  
Mateus Borba Cardoso ◽  
Watson Loh

2021 ◽  
Author(s):  
Evelyn Frontera ◽  
Martin F Desimone ◽  
Mauricio C De Marzi ◽  
Liliana N Guerra

Background: The addition of 5 mM N-acetylcysteine (NAC) to 3T3-L1 adipocytes culture inhibits the accumulation of triglycerides (Tg) by 50%, but after 48 h uptake was only 16% of total NAC available. Based on these results, the aim of this study is to increase the NAC cellular uptake by encapsulating it in silica nanoparticles (NPs). Materials & methods: Silica NPs, 20 ± 4.5 nm in size, were developed, with an inner cavity loaded with 5 mM NAC. At 48 h after treatment, there was a dose-dependent cytotoxic effect. We attempted to reduce the cytotoxicity of silica NPs by coating them with bovine serum albumin. Results: While we obtained nontoxic bovine serum albumin coated NPs, their effect on Tg cellular accumulation was also reduced.


2018 ◽  
Vol 340 ◽  
pp. 42-50 ◽  
Author(s):  
Valentina Nairi ◽  
Sara Medda ◽  
Marco Piludu ◽  
Maria Francesca Casula ◽  
Maria Vallet-Regì ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (109) ◽  
pp. 107452-107462 ◽  
Author(s):  
Hang Song ◽  
Chang Yang ◽  
Alula Yohannes ◽  
Shun Yao

In this work, silica gel (SiO2) was modified with an acidic ionic liquid (Im+·HSO4−) and the product was characterized using infrared spectroscopy, thermogravimetric analysis and elemental measurement.


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