scholarly journals A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study

2017 ◽  
Vol 8 (4) ◽  
pp. 2795-2803 ◽  
Author(s):  
Zi-Ru Dai ◽  
Lei Feng ◽  
Qiang Jin ◽  
Hailing Cheng ◽  
Yan Li ◽  
...  

A practical strategy was proposed and successfully used to design and develop an isoform-specific probe for a given enzyme.

2021 ◽  
Vol 328 ◽  
pp. 129034 ◽  
Author(s):  
Yanpeng Dai ◽  
Tianzi Xue ◽  
Hefang Ji ◽  
Pan Zhang ◽  
Dongdong Zhang ◽  
...  

2016 ◽  
Vol 52 (10) ◽  
pp. 2055-2058 ◽  
Author(s):  
Ivan Peran ◽  
Matthew D. Watson ◽  
Osman Bilsel ◽  
Daniel P. Raleigh

Selenomethionine is a short range quencher of p-cyanophenylalanine fluorescence and these residues provide a site-specific probe of protein helical structure.


2019 ◽  
Vol 11 (8) ◽  
pp. 2195 ◽  
Author(s):  
Chen-Yi Sun ◽  
Yin-Guang Chen ◽  
Rong-Jing Wang ◽  
Shih-Chi Lo ◽  
Jyh-Tyng Yau ◽  
...  

The green building certification system of Taiwan, EEWH (Ecology, Energy Saving, Waste Reduction and Health), has been in operation for more than 20 years (since 1999). In order to understand the relationship between green building certification and the construction costs of residential buildings, this study obtained 37 green building-certified residential cases and 36 general residential cases available from public information and conducted a comparative analysis. The results of this study showed that the average construction cost of a green building certification residential building was only 1.58% higher than a general residential building, indicating that green building certification does not require a large increase in costs. However, for residential buildings, achieving a high-grade (gold-grade or diamond-grade) green building certification means an increase of 6.7% to 9.3% in construction costs. This shows that the pursuit of higher levels of green building certification does require higher construction costs. In addition, the results of this study can not only provide important references for the government in making green building policies, but also offer a practical strategy for developers for decision-making.


Author(s):  
Dashamir Asani ◽  
Dode Prenga

Here we consider some proposal-steps in the calculation of the shadow economy as a latent or simply response variable in the models that involve high volatile observable as the money aggregates etc., and if the number of data point is small. In this case we propose to check for possible extreme behavior or self-organization regimes present in the series by testing e log-periodic fit to the data. To improve the linear regressions critical points (if found) have been excluded from series by simply truncating them. Next, the presence of more general regimes is analyzed using empirical mode decomposition techniques, and we estimate that the best truncated series to be used should exclude the edges of such regimes. In the case of short term regimes, we propose to use series in intervals that include many cycles. This technique worked for the calculation of informal economy in the Republic of Macedonia for the short period of [2004, 2016] but it is supposed to improve calculation for other cases as well


2020 ◽  
Vol 178 ◽  
pp. 108366 ◽  
Author(s):  
Ji-Ting Hou ◽  
Bingya Wang ◽  
Shan Wang ◽  
Yongquan Wu ◽  
Ye-Xin Liao ◽  
...  
Keyword(s):  

2019 ◽  
Vol 131 (39) ◽  
pp. 13752-13752
Author(s):  
Jing Ning ◽  
Wei Wang ◽  
Guangbo Ge ◽  
Peng Chu ◽  
Feida Long ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (18) ◽  
pp. 6125-6129 ◽  
Author(s):  
Chenchen Li ◽  
Wei Hu ◽  
Jinchen Wang ◽  
Xinjian Song ◽  
Xiaoxing Xiong ◽  
...  

A two-photon fluorescent probe with high selectivity and sensitivity was constructed and applied to image stroke-induced NO inflammation.


2021 ◽  
Vol 330 ◽  
pp. 129312
Author(s):  
Yue Chen ◽  
Qing-Qing He ◽  
Dan-Dan Wang ◽  
Fang-Yuan Wang ◽  
Xiao-Qing Guan ◽  
...  

2015 ◽  
Vol 7 (2) ◽  
pp. 443-457 ◽  
Author(s):  
Wanghui Jing ◽  
Ru Yan ◽  
Yitao Wang

A MIM-IDA-EPI-based strategy was proposed as a practical tool for the comprehensive characterization of the chemical profile of Mori Cortex.


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