scholarly journals Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

2016 ◽  
Vol 4 (21) ◽  
pp. 3639-3642 ◽  
Author(s):  
Arnaud Chaix ◽  
Khaled El Cheikh ◽  
Elise Bouffard ◽  
Marie Maynadier ◽  
Dina Aggad ◽  
...  

Porous silicon nanoparticles grafted with a mannose-6-phosphate analogue were designed for targeting prostate cancer cells.

RSC Advances ◽  
2015 ◽  
Vol 5 (55) ◽  
pp. 44660-44665 ◽  
Author(s):  
Bing Xia ◽  
Bin Wang ◽  
Wenyi Zhang ◽  
Jisen Shi

Styrene-terminated PSiNPs were fabricated for high loading of doxorubicin via π-stacking, which exhibited an excellent capability for killing cancer cells.


2015 ◽  
Vol 3 (12) ◽  
pp. 1555-1565 ◽  
Author(s):  
M. Hasanzadeh Kafshgari ◽  
M. Alnakhli ◽  
B. Delalat ◽  
S. Apostolou ◽  
F. J. Harding ◽  
...  

Polyethyleneimine-coated mesoporous silicon nanoparticles efficiently deliver siRNA in glioblastoma cells, subsequently reducing the protein expression of a chemotherapy resistance gene by 70% within 72 hours.


2015 ◽  
Vol 6 (4) ◽  
pp. 2411-2418 ◽  
Author(s):  
Sudarson Sekhar Sinha ◽  
Dilip K. Paul ◽  
Rajashekhar Kanchanapally ◽  
Avijit Pramanik ◽  
Suhash Reddy Chavva ◽  
...  

Development of a long-range TPS ruler for the screening of prostate cancer cells with sensitivity of 5 cells per mL level is demonstrated.


Endocrinology ◽  
2003 ◽  
Vol 144 (3) ◽  
pp. 955-966 ◽  
Author(s):  
Beverly S. Schaffer ◽  
Ming-Fong Lin ◽  
James C. Byrd ◽  
Jung H. Y. Park ◽  
Richard G. MacDonald

2021 ◽  
Vol 9 (1) ◽  
pp. 133-147
Author(s):  
Terence Tieu ◽  
Marcin Wojnilowicz ◽  
Pie Huda ◽  
Kristofer J. Thurecht ◽  
Helmut Thissen ◽  
...  

Targeted delivery of chemotherapeutics to cancer cells has the potential to yield high drug concentrations in cancer cells while minimizing any unwanted side effects.


2019 ◽  
Vol 20 (11) ◽  
pp. 2809
Author(s):  
Elise Bouffard ◽  
Chiara Mauriello Jimenez ◽  
Khaled El Cheikh ◽  
Marie Maynadier ◽  
Ilaria Basile ◽  
...  

The aim of the present work is the development of highly efficient targeting molecules to specifically address mesoporous silica nanoparticles (MSNs) designed for the photodynamic therapy (PDT) of prostate cancer. We chose the strategy to develop a novel compound that allows the improvement of the targeting of the cation-independent mannose 6-phosphate receptor, which is overexpressed in prostate cancer. This original sugar, a dimannoside-carboxylate (M6C-Man) grafted on the surface of MSN for PDT applications, leads to a higher endocytosis and thus increases the efficacy of MSNs.


2017 ◽  
Vol 29 (39) ◽  
pp. 1703309 ◽  
Author(s):  
Dokyoung Kim ◽  
Jinyoung Kang ◽  
Taejun Wang ◽  
Hye Gun Ryu ◽  
Jonathan M. Zuidema ◽  
...  

2015 ◽  
Vol 7 (41) ◽  
pp. 23197-23204 ◽  
Author(s):  
Alexandra Correia ◽  
Mohammad-Ali Shahbazi ◽  
Ermei Mäkilä ◽  
Sérgio Almeida ◽  
Jarno Salonen ◽  
...  

2014 ◽  
Vol 26 (45) ◽  
pp. 7643-7648 ◽  
Author(s):  
Emilie Secret ◽  
Marie Maynadier ◽  
Audrey Gallud ◽  
Arnaud Chaix ◽  
Elise Bouffard ◽  
...  

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