Simple and rational design of a polymer nano-platform for high performance of HCV related miR-122 reduction in the liver

2018 ◽  
Vol 6 (10) ◽  
pp. 2667-2680 ◽  
Author(s):  
Hao Fu ◽  
XiangYu Zhang ◽  
Qi Wang ◽  
Yin Sun ◽  
Lei Liu ◽  
...  
Keyword(s):  
Triblock Copolymer ◽  
High Performance ◽  
Rational Design ◽  
Loading Capacity

Efficient long-term liver specific miR-122 reduction is achieved by utilizing high antagomir loading capacity NPs consisting of an mPEG-b-PLGA-b-PLL triblock copolymer.

Rational design of graphene/porous carbon aerogels for high-performance flexible all-solid-state supercapacitors

2014 ◽  
Vol 2 (28) ◽  
pp. 10895-10903 ◽  
Author(s):  
Hong-Fei Ju ◽  
Wei-Li Song ◽  
Li-Zhen Fan
Keyword(s):  
Solid State ◽  
Porous Carbon ◽  
High Performance ◽  
Rational Design ◽  
Electrode Materials ◽  
Carbon Aerogels ◽  
Cycle Stability ◽  
Green Process ◽  
Excellent Electrochemical Performance

Graphene/porous carbon aerogels were rationally designed by a simple green process, exhibiting excellent electrochemical performance and long-term cycle stability as the electrode materials in flexible all-solid-state supercapacitors.

Efficient Co-Harvesting of Solar Energy and Low-Grade Heat by Molecular Photoswitches for High Energy Density, Long-Term Stable Solar Thermal Battery

2019 ◽  
Author(s):  
Zhao-Yang Zhang ◽  
Tao LI
Keyword(s):  
Energy Density ◽  
Solar Energy ◽  
High Performance ◽  
High Energy ◽  
Solar Thermal ◽  
High Energy Density ◽  
Low Grade ◽  
Thermal Battery ◽  
Low Grade Heat

Solar energy and ambient heat are two inexhaustible energy sources for addressing the global challenge of energy and sustainability. Solar thermal battery based on molecular switches that can store solar energy and release it as heat has recently attracted great interest, but its development is severely limited by both low energy density and short storage stability. On the other hand, the efficient recovery and upgrading of low-grade heat, especially that of the ambient heat, has been a great challenge. Here we report that solar energy and ambient heat can be simultaneously harvested and stored, which is enabled by room-temperature photochemical crystal-to-liquid transitions of small-molecule photoswitches. The two forms of energy are released together to produce high-temperature heat during the reverse photochemical phase change. This strategy, combined with molecular design, provides high energy density of 320-370 J/g and long-term storage stability (half-life of about 3 months). On this basis, we fabricate high-performance, flexible film devices of solar thermal battery, which can be readily recharged at room temperature with good cycling ability, show fast rate of heat release, and produce high-temperature heat that is >20<sup> o</sup>C higher than the ambient temperature. Our work opens up a new avenue to harvest ambient heat, and demonstrate a feasible strategy to develop high-performance solar thermal battery.

Efficient Co-Harvesting of Solar Energy and Low-Grade Heat by Molecular Photoswitches for High Energy Density, Long-Term Stable Solar Thermal Battery

2019 ◽  
Author(s):  
Zhao-Yang Zhang ◽  
Tao LI
Keyword(s):  
Energy Density ◽  
Solar Energy ◽  
High Performance ◽  
High Energy ◽  
Solar Thermal ◽  
High Energy Density ◽  
Low Grade ◽  
Thermal Battery ◽  
Low Grade Heat

Solar energy and ambient heat are two inexhaustible energy sources for addressing the global challenge of energy and sustainability. Solar thermal battery based on molecular switches that can store solar energy and release it as heat has recently attracted great interest, but its development is severely limited by both low energy density and short storage stability. On the other hand, the efficient recovery and upgrading of low-grade heat, especially that of the ambient heat, has been a great challenge. Here we report that solar energy and ambient heat can be simultaneously harvested and stored, which is enabled by room-temperature photochemical crystal-to-liquid transitions of small-molecule photoswitches. The two forms of energy are released together to produce high-temperature heat during the reverse photochemical phase change. This strategy, combined with molecular design, provides high energy density of 320-370 J/g and long-term storage stability (half-life of about 3 months). On this basis, we fabricate high-performance, flexible film devices of solar thermal battery, which can be readily recharged at room temperature with good cycling ability, show fast rate of heat release, and produce high-temperature heat that is >20<sup> o</sup>C higher than the ambient temperature. Our work opens up a new avenue to harvest ambient heat, and demonstrate a feasible strategy to develop high-performance solar thermal battery.

Use Of Tai Chi Elements To Increase Respiratory Amplitude

2019 ◽  
pp. 11-20
Author(s):  
Mihai-Alexandru Citea ◽  
Marius Neculaes
Keyword(s):  
High Performance ◽  
Tai Chi ◽  
Sports Club ◽  
Optimal Functioning ◽  
Physiological Adaptations ◽  
Competitive Activity ◽  
Abdominal Breathing ◽  
Study Participants ◽  
Different Levels

High performance sport has a major impact on the physiological adaptations of the respiratory system. The importance of the optimal functioning of this system is essential to achieve top results in high performance sport but also in maintaining a long term health status. Science journals present numerous studies that highlight the benefits of practicing Tai Chi on the general population, with effects ranging from improving cardiac function, to influencing the immune system. The purpose of this study is to identify whether by practicing Tai Chi forms a athlete can change their breathing pattern and develop their respiratory amplitude. The subjects of the study were 22 fencing practitioners, accredited at the Iași Municipal Sports Club (C.S.M. Iași), aged between 14 and 18 years, with over 3 years of competitive activity. Materials and method: The study participants were evaluated initially and at the end of 7 months of practice. The frequency was 3 sessions per week, and the duration of each session was 20-30 minutes. The evaluation consisted in measuring the circumference of the thorax at 3 different levels: subaxillary, medial thorax (T6-T7) and lower rib (diaphragmatic) in maximal inspiration and expiration. Conclusions: A constant evolution is observed in most of the exposed cases. In cases where this evolution is not visible, a change in the breathing mode can be noticed, transforming from an upper rib breathing into a thoracic or abdominal breathing. With the exception of one case, all subjects had an improvement of the value in the lower rib level.

scholarly journals Review on Development and Dental Applications of Polyetheretherketone-Based Biomaterials and Restorations

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 408 ◽  
Author(s):  
Ludan Qin ◽  
Shuo Yao ◽  
Jiaxin Zhao ◽  
Chuanjian Zhou ◽  
Thomas W. Oates ◽  
...  
Keyword(s):  
High Performance ◽  
Dental Resin ◽  
Oral Environment ◽  
Inert Surface ◽  
Oral Implant ◽  
Long Term Performance ◽  
Dental Applications ◽  
Term Performance ◽  
Orthopedic Applications

Polyetheretherketone (PEEK) is an important high-performance thermoplastic. Its excellent strength, stiffness, toughness, fatigue resistance, biocompatibility, chemical stability and radiolucency have made PEEK attractive in dental and orthopedic applications. However, PEEK has an inherently hydrophobic and chemically inert surface, which has restricted its widespread use in clinical applications, especially in bonding with dental resin composites. Cutting edge research on novel methods to improve PEEK applications in dentistry, including oral implant, prosthodontics and orthodontics, is reviewed in this article. In addition, this article also discusses innovative surface modifications of PEEK, which are a focus area of active investigations. Furthermore, this article also discusses the necessary future studies and clinical trials for the use of PEEK in the human oral environment to investigate its feasibility and long-term performance.

Rational Design of a High Performance and Robust Solar Evaporator via 3D‐Printing Technology

2021 ◽  
pp. 2102649
Author(s):  
Sourav Chaule ◽  
Jongha Hwang ◽  
Seong‐Ji Ha ◽  
Jihun Kang ◽  
Jong‐Chul Yoon ◽  
...  
Keyword(s):  
3D Printing ◽  
High Performance ◽  
Rational Design ◽  
Printing Technology ◽  
3D Printing Technology

Interpenetrating Gels as Conducting/Adhering Matrices Enabling High-Performance Silicon Anodes

2021 ◽  
Author(s):  
Tingting Xia ◽  
Chengfei Xu ◽  
Pengfei Dai ◽  
Xiaoyun Li ◽  
Riming Lin ◽  
...  
Keyword(s):  
Energy Storage ◽  
High Performance ◽  
Electrode Materials ◽  
Three Dimensional ◽  
Electrochemical Energy Storage ◽  
Active Materials ◽  
Silicon Anodes ◽  
Weak Binding ◽  
Binding Forces

Three-dimensional (3D) conductive polymers are promising conductive matrices for electrode materials toward electrochemical energy storage. However, their fragile nature and weak binding forces with active materials could not guarantee long-term...

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