scholarly journals The ozonolysis of isoprene in a cryogenic buffer gas cell by high resolution microwave spectroscopy

2018 ◽  
Vol 20 (24) ◽  
pp. 16828-16834 ◽  
Author(s):  
Jessica P. Porterfield ◽  
Sandra Eibenberger ◽  
David Patterson ◽  
Michael C. McCarthy

A novel approach has been developed for branching ratios analysis, with rapid sampling rate, short reaction times (10 s), and high sensitivity (ppb).

2019 ◽  
Vol 90 (5) ◽  
pp. 053104 ◽  
Author(s):  
Jessica P. Porterfield ◽  
Lincoln Satterthwaite ◽  
Sandra Eibenberger ◽  
David Patterson ◽  
Michael C. McCarthy

Author(s):  
Kazumichi Ogura ◽  
Michael M. Kersker

Backscattered electron (BE) images of GaAs/AlGaAs super lattice structures were observed with an ultra high resolution (UHR) SEM JSM-890 with an ultra high sensitivity BE detector. Three different types of super lattice structures of GaAs/AlGaAs were examined. Each GaAs/AlGaAs wafer was cleaved by a razor after it was heated for approximately 1 minute and its crosssectional plane was observed.First, a multi-layer structure of GaAs (100nm)/AlGaAs (lOOnm) where A1 content was successively changed from 0.4 to 0.03 was observed. Figures 1 (a) and (b) are BE images taken at an accelerating voltage of 15kV with an electron beam current of 20pA. Figure 1 (c) is a sketch of this multi-layer structure corresponding to the BE images. The various layers are clearly observed. The differences in A1 content between A1 0.35 Ga 0.65 As, A1 0.4 Ga 0.6 As, and A1 0.31 Ga 0.69 As were clearly observed in the contrast of the BE image.


Author(s):  
T. M. Weatherby ◽  
P.H. Lenz

Crustaceans, as well as other arthropods, are covered with sensory setae and hairs, including mechanoand chemosensory sensillae with a ciliary origin. Calanoid copepods are small planktonic crustaceans forming a major link in marine food webs. In conjunction with behavioral and physiological studies of the antennae of calanoids, we undertook the ultrastructural characterization of sensory setae on the antennae of Pleuromamma xiphias.Distal mechanoreceptive setae exhibit exceptional behavioral and physiological performance characteristics: high sensitivity (<10 nm displacements), fast reaction times (<1 msec latency) and phase locking to high frequencies (1-2 kHz). Unusual structural features of the mechanoreceptors are likely to be related to their physiological sensitivity. These features include a large number (up to 3000) of microtubules in each sensory cell dendrite, arising from or anchored to electron dense rods associated with the ciliary basal body microtubule doublets. The microtubules are arranged in a regular array, with bridges between and within rows. These bundles of microtubules extend far into each mechanoreceptive seta and terminate in a staggered fashion along the dendritic membrane, contacting a large membrane surface area and providing a large potential site of mechanotransduction.


Author(s):  
Abdallah Naser ◽  
Ahmad Lotfi ◽  
Joni Zhong

AbstractHuman distance estimation is essential in many vital applications, specifically, in human localisation-based systems, such as independent living for older adults applications, and making places safe through preventing the transmission of contagious diseases through social distancing alert systems. Previous approaches to estimate the distance between a reference sensing device and human subject relied on visual or high-resolution thermal cameras. However, regular visual cameras have serious concerns about people’s privacy in indoor environments, and high-resolution thermal cameras are costly. This paper proposes a novel approach to estimate the distance for indoor human-centred applications using a low-resolution thermal sensor array. The proposed system presents a discrete and adaptive sensor placement continuous distance estimators using classification techniques and artificial neural network, respectively. It also proposes a real-time distance-based field of view classification through a novel image-based feature. Besides, the paper proposes a transfer application to the proposed continuous distance estimator to measure human height. The proposed approach is evaluated in different indoor environments, sensor placements with different participants. This paper shows a median overall error of $$\pm 0.2$$ ± 0.2  m in continuous-based estimation and $$96.8\%$$ 96.8 % achieved-accuracy in discrete distance estimation.


Viruses ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 749
Author(s):  
Julia Butt ◽  
Rajagopal Murugan ◽  
Theresa Hippchen ◽  
Sylvia Olberg ◽  
Monique van Straaten ◽  
...  

The emerging SARS-CoV-2 pandemic entails an urgent need for specific and sensitive high-throughput serological assays to assess SARS-CoV-2 epidemiology. We, therefore, aimed at developing a fluorescent-bead based SARS-CoV-2 multiplex serology assay for detection of antibody responses to the SARS-CoV-2 proteome. Proteins of the SARS-CoV-2 proteome and protein N of SARS-CoV-1 and common cold Coronaviruses (ccCoVs) were recombinantly expressed in E. coli or HEK293 cells. Assay performance was assessed in a COVID-19 case cohort (n = 48 hospitalized patients from Heidelberg) as well as n = 85 age- and sex-matched pre-pandemic controls from the ESTHER study. Assay validation included comparison with home-made immunofluorescence and commercial enzyme-linked immunosorbent (ELISA) assays. A sensitivity of 100% (95% CI: 86–100%) was achieved in COVID-19 patients 14 days post symptom onset with dual sero-positivity to SARS-CoV-2 N and the receptor-binding domain of the spike protein. The specificity obtained with this algorithm was 100% (95% CI: 96–100%). Antibody responses to ccCoVs N were abundantly high and did not correlate with those to SARS-CoV-2 N. Inclusion of additional SARS-CoV-2 proteins as well as separate assessment of immunoglobulin (Ig) classes M, A, and G allowed for explorative analyses regarding disease progression and course of antibody response. This newly developed SARS-CoV-2 multiplex serology assay achieved high sensitivity and specificity to determine SARS-CoV-2 sero-positivity. Its high throughput ability allows epidemiologic SARS-CoV-2 research in large population-based studies. Inclusion of additional pathogens into the panel as well as separate assessment of Ig isotypes will furthermore allow addressing research questions beyond SARS-CoV-2 sero-prevalence.


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