A biodegradable fluorescent nanohybrid for photo-driven tumor diagnosis and tumor growth inhibition

Nanoscale ◽  
2018 ◽  
Vol 10 (40) ◽  
pp. 19082-19091 ◽  
Author(s):  
Rajendra Prasad ◽  
Deepak S. Chauhan ◽  
Amit S. Yadav ◽  
Janhavi Devrukhkar ◽  
Barkha Singh ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Growth ◽  
Growth Inhibition ◽  
Tumor Growth Inhibition ◽  
Oxygen Species ◽  
Deep Tissue ◽  
On Demand ◽  
Cancer Cell Death ◽  
Successful Design ◽  
Fluorescent Carbon Dots

A successful design of a novel red fluorescent carbon dots liposomal nanopitchers for deep tissue visualization and on demand phototriggered combined cancer therapy. The laser irradiation produces heat and reactive oxygen species that cause cancer cell death and tumor growth inhibition.

scholarly journals Close Interactions between Mesenchymal Stem Cells and Neuroblastoma Cell Lines Lead to Tumor Growth Inhibition

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e48654 ◽  
Author(s):  
Giovanna Bianchi ◽  
Fabio Morandi ◽  
Michele Cilli ◽  
Antonio Daga ◽  
Chiara Bocelli-Tyndall ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Tumor Growth ◽  
Growth Inhibition ◽  
Cell Lines ◽  
Neuroblastoma Cell ◽  
Tumor Growth Inhibition ◽  
Neuroblastoma Cell Lines

Diverse Roles of Macrophage Matrix Metalloproteinases in Tissue Destruction and Tumor Growth

1999 ◽  
Vol 82 (08) ◽  
pp. 846-849 ◽  
Author(s):  
Steven Shapiro
Keyword(s):  
Tumor Growth ◽  
Growth Inhibition ◽  
Gene Targeting ◽  
Critical Role ◽  
Human Biology ◽  
Disease Models ◽  
Tumor Growth Inhibition ◽  
Mouse Macrophage ◽  
Tissue Destruction

SummaryIn the mouse, macrophage elastase is critical to macrophage proteolysis. The use of gene-targeting has uncovered both pathological roles, including destructive effects in aneurysm formation and emphysema, and physiological roles, such as tumor growth inhibition and regulation of inflammation. Translation of findings from mouse to human biology depends upon how well the disease models replicate the human conditions and the similarity of enzyme profile between species. We know that human MMP-12 is associated with these diseases, but as opposed to the mouse, other MMPs may also be of importance (MMP-9, and perhaps MMP-7, in particular). Our interpretation is that findings in mice reflect the critical role of macrophage proteolysis in these disease processes.

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