A twin-tailed tadpole-shaped amphiphilic copolymer of poly(ethylene glycol) and cyclic poly(ε-caprolactone): synthesis, self-assembly and biomedical applications

2018 ◽  
Vol 9 (33) ◽  
pp. 4343-4353 ◽  
Author(s):  
Yanyan Zhou ◽  
Lei Li ◽  
Wei Chen ◽  
Dian Li ◽  
Nianchen Zhou ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Amphiphilic Copolymer ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

A tadpole-shaped amphiphilic copolymer containing cyclic PCL and two PEG tails, PEG-b-(c-PCL)-b-PEG, was rationally designed and synthesized.

Polysarcosine: The Best Alternative of Poly (Ethylene Glycol)

2020 ◽  
Vol 04 ◽  
Author(s):  
Manu Singhai ◽  
Sankha Bhattacharya
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Protein Delivery ◽  
Ring Opening ◽  
Biomedical Applications ◽  
High Vacuum ◽  
Ring Opening Polymerization ◽  
Poly Ethylene Glycol ◽  
Biologically Relevant ◽  
Poly Ethylene

Abstract:: Polysarcosine (psar) is a non-ionic hydrophilic polypeptoid with numerous biologically relevant properties. Polysarcosine is poly (n-methylated glycine) and has been reported first by wesley and co-workers in the 1920s. Polysarcosine was first synthesized via ring-opening polymerization (rop) of sarcosine n-carboxyanhydride, using high-vacuum techniques. Overall, findings highlight the potential of poly(sarcosine) as an alternative corona-forming polymer to poly (ethylene glycol)-based analogues of (polymerization-induced self-assembly) pisa assemblies for use in various pharmaceutical and biomedical applications. Numerous studies suggested that such polypeptoids hold enormous potential for many biomedical applications, including protein delivery, colloidal stabilization, and nanomedicine.

Synthesis and thermo-responsive self-assembly behavior of amphiphilic copolymer β-CD–(PCL–P(MEO2MA-co-PEGMA))21 for the controlled intracellular delivery of doxorubicin

RSC Advances ◽  
2016 ◽  
Vol 6 (56) ◽  
pp. 50993-51004 ◽  
Author(s):  
Beibei Lu ◽  
Lei Li ◽  
Lulu Wei ◽  
Xuhong Guo ◽  
Jun Hou ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Self Assembly ◽  
Intracellular Delivery ◽  
Amphiphilic Copolymer ◽  
Poly Ethylene Glycol ◽  
Glycol Methacrylate ◽  
Ethyl Methacrylate ◽  
Assembly Behavior ◽  
Poly Ethylene

Well-defined amphiphilic β-cyclodextrin star-shaped copolymers with poly(ε-caprolactone)–poly(2-(2-methoxyethoxy)ethyl methacrylate)-co-poly(ethylene glycol)methacrylate) (β-CD–(PCL–P(MEO2MA-co-PEGMA))21 were synthesized via (ROP) and (ATRP).

Facile synthesis and self-assembly of amphiphilic polydimethylsiloxane with poly(ethylene glycol) moieties via thiol-ene click reaction

RSC Advances ◽  
2015 ◽  
Vol 5 (63) ◽  
pp. 50955-50961 ◽  
Author(s):  
Yong Xia ◽  
Hongtao Yao ◽  
Zhihui Miao ◽  
Yun Ma ◽  
Meifang Cui ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Click Chemistry ◽  
Self Assembly ◽  
Click Reaction ◽  
Amphiphilic Copolymer ◽  
Efficient Synthesis ◽  
Poly Ethylene Glycol ◽  
Facile Synthesis ◽  
Poly Ethylene

A facile and efficient synthesis of polysiloxane-based amphiphilic copolymer via thiol-ene click chemistry.

Synthesis and self-assembly behaviour of poly(Nα-Boc-l-tryptophan)-block-poly(ethylene glycol)-block-poly(Nα-Boc-l-tryptophan)

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Triblock Copolymers ◽  
Potential Drug ◽  
Poly Ethylene Glycol ◽  
Drug Delivery Applications ◽  
Poly Ethylene ◽  
First Time

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.

Preparation and characterization of poly (ethylene glycol) grafted Ca-alginate fibers by γ-irradiation for biomedical applications

2013 ◽  
Vol 27 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Md. Kamal Khan ◽  
Mohammed Mizanur Rahman ◽  
Bodrun Nesa ◽  
Romana Nasrin ◽  
Swajal Molla ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Poly Ethylene Glycol ◽  
Γ Irradiation ◽  
Alginate Fibers ◽  
Poly Ethylene ◽  
Ca Alginate
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