9t18:1 and 11t18:1 activate the MAPK pathway to regulate the expression of PLA2 and cause inflammation in HUVECs

2020 ◽  
Vol 11 (1) ◽  
pp. 649-661
Author(s):  
Sheng-Ben Hu ◽  
Qian Zou ◽  
Xin Lv ◽  
Ruo-Lin Zhou ◽  
Xian Niu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Endothelial Cells ◽  
Vascular Endothelial Cells ◽  
Mapk Pathway ◽  
Vascular Diseases ◽  
Vascular Endothelial ◽  
Apoptosis And Inflammation

trans fatty acids (TFAs) have been reported to promote vascular diseases mainly by promoting apoptosis and inflammation of vascular endothelial cells.

Regulation of glutathione peroxidase (GSHPx) activity in human vascular endothelial cells by fatty acids

1996 ◽  
Vol 24 (2) ◽  
pp. 176S-176S ◽  
Author(s):  
ANITA J. CROSBY ◽  
KLAUS W. J. WAHLE ◽  
GARRY G. DUTHIE ◽  
PHILIP C. MORRICE
Keyword(s):  
Fatty Acids ◽  
Endothelial Cells ◽  
Glutathione Peroxidase ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Gshpx Activity

scholarly journals Glycoconjugates and Related Molecules in Human Vascular Endothelial Cells

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Norihiko Sasaki ◽  
Masashi Toyoda
Keyword(s):  
Endothelial Cells ◽  
Blood Cell ◽  
Vascular Endothelial Cells ◽  
Vascular Diseases ◽  
Cell Trafficking ◽  
Vascular Endothelial ◽  
Carbohydrate Composition ◽  
Vasomotor Tone ◽  
Physiological Functions ◽  
Functional Roles

Vascular endothelial cells (ECs) form the inner lining of blood vessels. They are critically involved in many physiological functions, including control of vasomotor tone, blood cell trafficking, hemostatic balance, permeability, proliferation, survival, and immunity. It is considered that impairment of EC functions leads to the development of vascular diseases. The carbohydrate antigens carried by glycoconjugates (e.g., glycoproteins, glycosphingolipids, and proteoglycans) mainly present on the cell surface serve not only as marker molecules but also as functional molecules. Recent studies have revealed that the carbohydrate composition of the EC surface is critical for these cells to perform their physiological functions. In this paper, we consider the expression and functional roles of endogenous glycoconjugates and related molecules (galectins and glycan-degrading enzymes) in human ECs.

scholarly journals G-CSF Protects Human Brain Vascular Endothelial Cells Injury Induced by High Glucose, Free Fatty Acids and Hypoxia through MAPK and Akt Signaling

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0120707 ◽  
Author(s):  
Jingjing Su ◽  
Houguang Zhou ◽  
Yinghong Tao ◽  
Jingchun Guo ◽  
Zhuangli Guo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Endothelial Cells ◽  
Human Brain ◽  
Free Fatty Acids ◽  
High Glucose ◽  
Vascular Endothelial Cells ◽  
Akt Signaling ◽  
Vascular Endothelial

Free fatty acids trigger apoptosis and inhibit cell cycle progression in human vascular endothelial cells

2003 ◽  
Vol 18 (1) ◽  
pp. 146-148 ◽  
Author(s):  
Michaela Artwohl ◽  
Michael Roden ◽  
Werner Waldhäusl ◽  
Angelika Freudenthaler ◽  
Sabina M. Baumgartner‐Parzer
Keyword(s):  
Cell Cycle ◽  
Fatty Acids ◽  
Endothelial Cells ◽  
Free Fatty Acids ◽  
Cell Cycle Progression ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial ◽  
Cycle Progression ◽  
Inhibit Cell Cycle Progression
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