Noninvasive ratiometric fluorescence imaging of γ‑glutamyltransferase activity using an activatable probe

The Analyst ◽  
2021 ◽  
Author(s):  
Zheng Huang ◽  
Ruibing An ◽  
Shixuan Wei ◽  
Jinfang Wang ◽  
Deju Ye
Keyword(s):  
Fluorescence Imaging ◽  
Malignant Tumors ◽  
Diagnosis And Treatment ◽  
Ratiometric Fluorescence ◽  
Accurate Detection ◽  
Activatable Probe

γ-Glutamyltranspeptidase (GGT) is an important aminopeptidase overexpressed in many malignant tumors, and accurate detection of its activity is useful for the diagnosis and treatment of tumors. Herein, we report a...

Ratiometric Fluorescence Imaging for the Distribution of Nucleic Acid Content in Living Cells and Human Tissue Sections

2020 ◽  
Author(s):  
Liu-Yi Liu ◽  
Yuping Zhao ◽  
Nan Zhang ◽  
Kang-Nan Wang ◽  
Minggang Tian ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Fluorescence Imaging ◽  
Human Tissue ◽  
Acid Content ◽  
Living Cells ◽  
Nucleic Acid Content ◽  
Ratiometric Fluorescence ◽  
Tissue Sections

Nanoscale Zeolitic Imidazolate Framework-8 for Ratiometric Fluorescence Imaging of MicroRNA in Living Cells

2017 ◽  
Vol 89 (22) ◽  
pp. 12351-12359 ◽  
Author(s):  
Jin-Tao Yi ◽  
Ting-Ting Chen ◽  
Jia Huo ◽  
Xia Chu
Keyword(s):  
Fluorescence Imaging ◽  
Living Cells ◽  
Ratiometric Fluorescence ◽  
Zeolitic Imidazolate Framework

scholarly journals Role and underlying mechanisms of the interstitial protein periostin in the diagnosis and treatment of malignant tumors (Review)

2017 ◽  
Author(s):  
Dong Ye ◽  
Zhi Shen ◽  
Shi Qiu ◽  
Qun Li ◽  
Guo Wang
Keyword(s):  
Malignant Tumors ◽  
Diagnosis And Treatment ◽  
Underlying Mechanisms

scholarly journals Application of Mass Spectrometry in Pancreatic Cancer Translational Research

2021 ◽  
Vol 11 ◽  
Author(s):  
Peng Ge ◽  
Yalan Luo ◽  
Haiyang Chen ◽  
Jiayue Liu ◽  
Haoya Guo ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Pancreatic Cancer ◽  
Malignant Tumors ◽  
Basic Research ◽  
Present Situation ◽  
Diagnosis And Treatment ◽  
Research Model ◽  
Comprehensive Diagnosis ◽  
Remarkable Progress ◽  
Made In

Pancreatic cancer (PC) is one of the most common malignant tumors in the digestive tract worldwide, with increased morbidity and mortality. In recent years, with the development of surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy, and the change of the medical thinking model, remarkable progress has been made in researching comprehensive diagnosis and treatment of PC. However, the present situation of diagnostic and treatment of PC is still unsatisfactory. There is an urgent need for academia to fully integrate the basic research and clinical data from PC to form a research model conducive to clinical translation and promote the proper treatment of PC. This paper summarized the translation progress of mass spectrometry (MS) in the pathogenesis, diagnosis, prognosis, and PC treatment to promote the basic research results of PC into clinical diagnosis and treatment.

Ratiometric Fluorescence Imaging of Cellular Glutathione

2011 ◽  
Vol 13 (11) ◽  
pp. 2799-2801 ◽  
Author(s):  
Gun-Joong Kim ◽  
Kiwon Lee ◽  
Hyockman Kwon ◽  
Hae-Jo Kim
Keyword(s):  
Fluorescence Imaging ◽  
Ratiometric Fluorescence

Rational design of stable heptamethine cyanines and development of a boimarker-activatable probe for detecting acute lung/kidney injury via NIR-II fluorescence imaging

The Analyst ◽  
2022 ◽  
Author(s):  
Juan Ouyang ◽  
Lihe Sun ◽  
Fang Zeng ◽  
Shuizhu Wu
Keyword(s):  
Fluorescence Imaging ◽  
Rational Design ◽  
Kidney Injury ◽  
High Quality ◽  
Enhanced Imaging ◽  
Activatable Probe

Developing high-quality dyes to construct activatable probes for analyte sensing via NIR-II fluorescence is critical to attain enhanced imaging depths and resolution. Heptamethine-cyanines can serve this purpose; however, they usually...

Field-portable ratiometric fluorescence imaging of dual-color label-free carbon dots for uranyl ions detection with cellphone-based optical platform

2020 ◽  
Vol 31 (11) ◽  
pp. 2925-2928 ◽  
Author(s):  
Jingjing Qian ◽  
Nana Cao ◽  
Jian Zhang ◽  
Jinjin Hou ◽  
Qian Chen ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Carbon Dots ◽  
Free Carbon ◽  
Uranyl Ions ◽  
Label Free ◽  
Ratiometric Fluorescence ◽  
Dual Color

scholarly journals Point-of-care Ratiometric Fluorescence Imaging of Tissue for the Diagnosis of Ovarian Cancer

Theranostics ◽  
2019 ◽  
Vol 9 (16) ◽  
pp. 4597-4607 ◽  
Author(s):  
Xiaobo Zhou ◽  
Yawei Liu ◽  
Qiyu Liu ◽  
Luzhe Yan ◽  
Meng Xue ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Fluorescence Imaging ◽  
Point Of Care ◽  
Ratiometric Fluorescence

A DNA-functionalized biomass nanoprobe for the targeted photodynamic therapy of tumor and ratiometric fluorescence imaging-based visual cancer cell identification/antitumor drug screening

The Analyst ◽  
2021 ◽  
Author(s):  
Pengxiang Lin ◽  
Liangliang Zhang ◽  
Dongxia Chen ◽  
Jiayao Xu ◽  
Yulong Bai ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Cancer Cell ◽  
Drug Screening ◽  
Antitumor Drug ◽  
Ratiometric Fluorescence ◽  
Cell Identification ◽  
Targeted Photodynamic Therapy

A DNA-functionalized biomass nanoprobe was developed for the targeted photodynamic therapy of tumor and ratiometric fluorescence imaging-based visual cancer cell identification/antitumor drug screening.

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