A metal-enhanced sensing platform for highly sensitive detection of C-Reactive Protein antibody and Rhodamine B, applications for cardiovascular disease and food safety

2021 ◽  
Author(s):  
Nguyen Thanh Thao ◽  
Thi Xoan Hoang ◽  
Thang Bach Phan ◽  
Jae Young Kim ◽  
Hanh Kieu Thi Ta ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Food Safety ◽  
Medical Diagnostics ◽  
C Reactive Protein ◽  
Enhanced Fluorescence ◽  
Reactive Protein ◽  
Sensing Platform ◽  
Highly Sensitive ◽  
Potential Applications ◽  
Highly Sensitive Detection

Potential applications of metal enhanced fluorescence (MEF) devices are associated with biosensors for the detection of trace amounts of biosciences, biotechnology, and pathogens that are relevant to medical diagnostics and...

Highly sensitive detection of C-reactive protein using a novel dissolution approach in a dye-doped silica nanoparticle-based fluorescence immunoassay

2017 ◽  
Vol 9 (6) ◽  
pp. 994-1003 ◽  
Author(s):  
Robert Nooney ◽  
Valerie Rebello ◽  
Gemma Keegan ◽  
Claire L. O'Connell ◽  
Daragh Byrne ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Silica Nanoparticle ◽  
Sensitive Detection ◽  
Fluorescence Immunoassay ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Enhanced Sensitivity ◽  
Disease Marker ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A novel dissolution approach was used to achieve enhanced sensitivity in a nanoparticle (NP) immunoassay for the detection of a cardiovascular disease marker, C-reactive protein (CRP).

A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein

2016 ◽  
Vol 52 (20) ◽  
pp. 3883-3886 ◽  
Author(s):  
Ryo Matsuura ◽  
Keiko Tawa ◽  
Yukiya Kitayama ◽  
Toshifumi Takeuchi
Keyword(s):  
Surface Plasmon ◽  
Synthetic Polymer ◽  
Sensitive Detection ◽  
C Reactive Protein ◽  
Enhanced Fluorescence ◽  
Reactive Protein ◽  
Sensing System ◽  
Highly Sensitive ◽  
Highly Sensitive Detection ◽  
Polymer Ligand

A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence.

One-step kinetics-based immunoassay for the highly sensitive detection of C-reactive protein in less than 30min

2014 ◽  
Vol 456 ◽  
pp. 32-37 ◽  
Author(s):  
Sandeep Kumar Vashist ◽  
Gregor Czilwik ◽  
Thomas van Oordt ◽  
Felix von Stetten ◽  
Roland Zengerle ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Highly Sensitive ◽  
One Step ◽  
Highly Sensitive Detection

Synthesis of grafted phosphorylcholine polymer layers as specific recognition ligands for C-reactive protein focused on grafting density and thickness to achieve highly sensitive detection

2015 ◽  
Vol 17 (15) ◽  
pp. 9951-9958 ◽  
Author(s):  
Yuri Kamon ◽  
Yukiya Kitayama ◽  
Akiko N. Itakura ◽  
Kyoko Fukazawa ◽  
Kazuhiko Ishihara ◽  
...  
Keyword(s):  
Layer Thickness ◽  
Thin Layers ◽  
Sensitive Detection ◽  
C Reactive Protein ◽  
Polymer Layers ◽  
Reactive Protein ◽  
Specific Recognition ◽  
Grafting Density ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

We studied the effects of layer thickness and grafting density of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) thin layers as specific ligands for the highly sensitive binding of C-reactive protein (CRP).

Fluorogenic nanocrystals for highly sensitive detection of C-reactive protein

2006 ◽  
Vol 153 (3) ◽  
pp. 54 ◽  
Author(s):  
K.-K. Sin ◽  
C.P.-Y. Chan ◽  
W.-M. Leung ◽  
M. Seydack ◽  
R. Renneberg
Keyword(s):  
Sensitive Detection ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Highly sensitive C-reactive protein (CRP) assay using metal-enhanced fluorescence (MEF)

2015 ◽  
Vol 17 (7) ◽  
Author(s):  
Yi Zhang ◽  
Gemma L. Keegan ◽  
Ondrej Stranik ◽  
Margaret E. Brennan-Fournet ◽  
Colette McDonagh
Keyword(s):  
C Reactive Protein ◽  
Enhanced Fluorescence ◽  
Metal Enhanced Fluorescence ◽  
Reactive Protein ◽  
Highly Sensitive

Highly sensitive C reactive protein in patients with metabolic syndrome and cardiovascular disease

2012 ◽  
Vol 5 (2) ◽  
pp. 98 ◽  
Author(s):  
PrabhaM Adhikari ◽  
SahanaD Acharya ◽  
JohnT Ramapuram ◽  
MuktaN Chowta ◽  
Rishav Sinha ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Highly Sensitive

Wash-free highly sensitive detection of C-reactive protein using gold derivatised triangular silver nanoplates

RSC Advances ◽  
2014 ◽  
Vol 4 (55) ◽  
pp. 29022-29031 ◽  
Author(s):  
Yi Zhang ◽  
Denise E. Charles ◽  
Deirdre M. Ledwith ◽  
Damian Aherne ◽  
Stephen Cunningham ◽  
...  
Keyword(s):  
Sensitive Detection ◽  
C Reactive Protein ◽  
Silver Nanoplates ◽  
Reactive Protein ◽  
Highly Sensitive ◽  
Triangular Silver Nanoplates ◽  
Highly Sensitive Detection

Rapid, wash-free highly sensitive detection of C-reactive protein is reported using nanoplate biosensor sols.

Nanodiagnostic Attainments and Clinical Perspectives on C-Reactive Protein: Cardiovascular Disease Risks Assessment

2020 ◽  
Vol 27 ◽  
Author(s):  
Iswary Letchumanan ◽  
M.K. Md Arshad ◽  
Subash C.B. Gopinath
Keyword(s):  
Cardiovascular Disease ◽  
Coronary Artery ◽  
High Performance ◽  
Colorimetric Assay ◽  
Medical Diagnostics ◽  
World Health ◽  
Enzyme Linked Immunosorbent Assay ◽  
C Reactive Protein ◽  
Electrical Measurements ◽  
Reactive Protein

: Cardiovascular disease (CVD) has become one of the leading causes of morbidity and mortality among men and women. According to the World Health Organization, ischemic heart disease is the major issue among the population due to narrowing of the coronary artery by the plaque formation on the artery wall and causes an inadequate flow of oxygen and blood to the heart, called ‘coronary artery disease’. Consequently, the death rate due to CVD has increased to 15 % in 2016 as compared to the past decade (on 2006), by 2016 it was ~17.6 million. This tremendous increment urges the development of a suitable biomarker for the rapid and early diagnosis. Currently, C-reactive protein (CRP) is considered as an outstanding biomarker among clinical researches for its quick and accurate outcome. Many techniques are used to diagnose cardiovascular disease, which include surface plasmon resonance, colorimetric assay, enzyme-linked immunosorbent assay, fluoro-immunoassays, chemiluminescent and by the electrical measurements. This review discusses these strategies and how current cutting-edge technologies enabled that development of high-performance detection methodologies. Concluding remarks have been made with the clinical significance and the usage of nanomaterial in medical diagnostics towards nanotheranostics.

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