Hypoxia and temperature dual-stimuli-responsive random copolymers: facile synthesis, self-assembly and controlled release of drug

2020 ◽  
Vol 44 (25) ◽  
pp. 10229-10238 ◽  
Author(s):  
Chenming Ji ◽  
Yinlu Deng ◽  
Hua Yuan ◽  
Yongzhen Wu ◽  
Weizhong Yuan

The micelles self-assembled from P(NIPAM-co-AA-co-NIA) copolymers presented hypoxia and temperature dual-stimuli-responsive properties and a controlled release of drug was achieved using them.

2018 ◽  
Vol 6 (42) ◽  
pp. 6817-6830 ◽  
Author(s):  
Wen Liu ◽  
Jian Dai ◽  
Wei Xue

Stimuli-responsive nanomaterial-based drug delivery systems that are able to actively target the tumor microenvironment, enhance intratumoral accumulation and release drugs at target sites are attractive therapeutic platforms at present.


2018 ◽  
Vol 9 (4) ◽  
pp. 463-471 ◽  
Author(s):  
Qingwei Li ◽  
Ziquan Cao ◽  
Guojie Wang

A multiple-stimuli-responsive polymer nanocarrier has been self-assembled for NIR/UV light- and pH-controlled cargo release.


2015 ◽  
Vol 44 (34) ◽  
pp. 15181-15188 ◽  
Author(s):  
Sudhakar Ganta ◽  
Dillip Kumar Chand

A multi-stimuli-responsive metallogel is obtained by the self-assembly of an already self-assembled trinuclear palladium(ii) based coordination ring of the rare M3L6 composition.


2014 ◽  
Vol 2 (34) ◽  
pp. 5576-5584 ◽  
Author(s):  
Sreedevi Krishnakumar ◽  
Karical R. Gopidas

Novel Fréchet-type dendron based organic nanodots exhibiting stimuli responsive reversible morphological transformation have been synthesized by a one-pot reaction which involves etching off gold core of a gold nanoparticle cored dendrimer. Self-assembled FDNs can be utilized for encapsulation and on-demand release of guests.


RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 43024-43028 ◽  
Author(s):  
Siyuan Yang ◽  
Shengsen Zhang ◽  
Hongjuan Wang ◽  
Hao Yu ◽  
Yueping Fang ◽  
...  

Self-assembly CuO nanospheres (CuONSs) and hollow Cu2O microspheres (Cu2OMSs) show an excellent adsorption performance for anionic dyes in water.


2015 ◽  
Vol 3 (28) ◽  
pp. 5690-5701 ◽  
Author(s):  
Krishnamoorthy Lalitha ◽  
Subbiah Nagarajan

The present work reports facile synthesis of pyrene coupled coumarin derivatives which could form self-assembled molecular gel and nano-flakes. The nanomaterials obtained via a self-assembly process could be potentially used in fluorescence imaging applications.


RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 19322-19330 ◽  
Author(s):  
Binoy Maiti ◽  
Sankar Maiti ◽  
Priyadarsi De

Side-chain stearic acid containing thermoresponsive and crystalline random copolymers are synthesized via RAFT technique, which self-assembled to spherical micellar structures in aqueous solution depending on stearate content in the copolymer.


2017 ◽  
Vol 53 (59) ◽  
pp. 8364-8367 ◽  
Author(s):  
Yujuan Zhou ◽  
Kecheng Jie ◽  
Feihe Huang

A selenium-containing pillar[5]arene-based macrocyclic amphiphile was prepared. This amphiphile self-assembled in water to form vesicles with redox responsiveness. Then, these pillar[5]arene-based vesicles were used in the controlled release of DOX.


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