A multiple emission bands NIR persistent luminescence nanoparticles [email protected]: Cr3+, Yb3+ for biological applications

Author(s):  
Yaling Lin ◽  
Jie Hu ◽  
Luyan Wu ◽  
Qilin Zou ◽  
Dejian Chen ◽  
...  

Persistent luminescence nanoparticles (PLNPs) emitting in the NIR window (700 - 1700 nm) have shown great promise in the field of fluorescence imaging due to their unique properties including the...

Author(s):  
Youliang Tian ◽  
Huiting Zhou ◽  
Quan Cheng ◽  
Huiping Dang ◽  
Hongyun Qian ◽  
...  

Fluorescence imaging in the second near-infrared window (NIR-II, 1000–1700 nm) holds great promise for in vivo imaging and imaging-guided phototherapy with deep penetration and high spatiotemporal resolution. It is very...


2019 ◽  
Vol 7 (7) ◽  
pp. 2873-2888 ◽  
Author(s):  
Xu Zhang ◽  
Xiaolong Liang ◽  
Xiaotu Ma ◽  
Rui Hou ◽  
Xiaoda Li ◽  
...  

Dye-conjugated cerasome loaded with DOX exhibited high stability and controllable drug release, holding great promise in colorectal cancer photothermal chemotherapy.


Nanoscale ◽  
2020 ◽  
Vol 12 (26) ◽  
pp. 14180-14187 ◽  
Author(s):  
Luyan Wu ◽  
Jie Hu ◽  
Qilin Zou ◽  
Yaling Lin ◽  
Decai Huang ◽  
...  

Y3(Al/Ga)5O12:Ce3+,Cr3+,Nd3+ nanocrystals with strong persistent luminescence in the NIR-II spectral region, which are highly desired for bioimaging, have been synthesized by a salt microemulsion method.


2018 ◽  
Vol 183 (11) ◽  
pp. 354-354 ◽  
Author(s):  
Sophie Favril ◽  
Eline Abma ◽  
Francesco Blasi ◽  
Emmelie Stock ◽  
Nausikaa Devriendt ◽  
...  

One of the major challenges in surgical oncology is the intraoperative discrimination of tumoural versus healthy tissue. Until today, surgeons rely on visual inspection and palpation to define the tumoural margins during surgery and, unfortunately, for various cancer types, the local recurrence rate thus remains unacceptably high. Near-infrared (NIR) fluorescence imaging is an optical imaging technique that can provide real-time preoperative and intraoperative information after administration of a fluorescent probe that emits NIR light once exposed to a NIR light source. This technique is safe, cost-effective and technically easy. Several NIR fluorescent probes are currently studied for their ability to highlight neoplastic cells. In addition, NIR fluorescence imaging holds great promise for sentinel lymph node mapping. The aim of this manuscript is to provide a literature review of the current organic NIR fluorescent probes tested in the light of human oncology and to introduce fluorescence imaging as a valuable asset in veterinary oncology.


2022 ◽  
Author(s):  
Bin Fang ◽  
Beilin Zhang ◽  
Rongxiu Zhai ◽  
Limin Wang ◽  
Yang Ding ◽  
...  

Rational design of mitochondrial viscosity probes with water-soluble two-photon (TP) fluorescence probe still remains a challenge in practical biological applications. Herein, three novel water-soluble TP active sulfosalt derivatives (Mito-Z, Mito-H,...


Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 153
Author(s):  
Hak-Sung Jung ◽  
Keir C. Neuman

Fluorescent nanodiamonds (FNDs) are a new class of carbon nanomaterials that offer great promise for biological applications such as cell labeling, imaging, and sensing due to their exceptional optical properties and biocompatibility. Implementation of these applications requires reliable and precise surface functionalization. Although diamonds are generally considered inert, they typically possess diverse surface groups that permit a range of different functionalization strategies. This review provides an overview of nanodiamond surface functionalization methods including homogeneous surface termination approaches (hydrogenation, halogenation, amination, oxidation, and reduction), in addition to covalent and non-covalent surface modification with different functional moieties. Furthermore, the subsequent coupling of biomolecules onto functionalized nanodiamonds is reviewed. Finally, biomedical applications of nanodiamonds are discussed in the context of functionalization.


Author(s):  
Jingwei Liu ◽  
Yanjie Liang ◽  
Shao Yan ◽  
Dongxun Chen ◽  
Shihai Miao ◽  
...  

Ultraviolet (UV) luminescent materials hold great promise for applications across a wide number of fields, whether environmental, biological or medical. However, luminescent materials with the capability to continue emitting UV...


2020 ◽  
Vol 13 (03) ◽  
pp. 2030006
Author(s):  
Wenzhao Yang ◽  
Sung-Liang Chen

Time-gated (TG) fluorescence imaging (TGFI) has attracted increasing attention within the biological imaging community, especially during the past decade. With rapid development of light sources, image devices, and a variety of approaches for TG implementation, TGFI has demonstrated numerous biological applications ranging from molecules to tissues. The paper presents inclusive TG implementation mainly based on optical choppers and electronic units for synchronization of fluorescence excitation and emission, which also serves as guidelines for researchers to build suited TGFI systems for selected applications. Note that a special focus will be put on TG implementation based on optical choppers for TGFI of long-lived probes (lifetime range from microseconds to milliseconds). Biological applications by TG imaging of recently developed luminescent probes are described.


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