Aiding the versatility of simple ammonium ionic liquid by the synthesis of bioactive 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinones derivatives.

2021 ◽  
Author(s):  
Satish Kumar Awasthi ◽  
Praachi Kakati ◽  
Preeti Singh ◽  
PRIYANKA YADAV
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Condensation Reaction ◽  
Hantzsch Reaction ◽  
Environment Friendly ◽  
Quinazolinone Derivatives ◽  
Biginelli Condensation ◽  
Ammonium Ionic Liquids

Simple ammonium ionic liquids [ILs] are the efficient, green, environment friendly catalyst in promoting Biginelli condensation reaction, Hantzsch reaction and Niementowski reaction to afford 1,2,3,4-tetrahydropyrimidine, 2-aminothiazole and quinazolinone derivatives respectively...

One-Pot Syntheses of 2H-Indazolo[2,1-B] Phthalazine-Triones Catalyzed by Ionic Iiquid

2011 ◽  
Vol 332-334 ◽  
pp. 1884-1887
Author(s):  
Fang Yang ◽  
Hong Jun Zang ◽  
Qing Kai Wang ◽  
Bo Wen Cheng ◽  
Yuan Lin Ren ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Condensation Reaction ◽  
Aromatic Aldehydes ◽  
One Pot

A simple and efficient one-pot method for the preparation of 2H-indazolo [2,1-b] phthalazine-triones from phthalhydrazide, dimedone and aromatic aldehydes has been developed using ionic liquids as catalysts. Two ionic liquid catalysts are described, and the ionic liquid [(CH2)4SO3HMIM]HSO4 catalyst is found to be more effective than [HMIM]HSO4 for this condensation reaction.

An effective and environment-friendly system for Cu NPs@RGO-catalyzed C–C homocoupling of aryl halides or arylboronic acids in ionic liquids under microwave irradiation

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 41108-41113 ◽  
Author(s):  
Hongyan Zhao ◽  
Guijie Mao ◽  
Huatao Han ◽  
Jinyi Song ◽  
Yang Liu ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Microwave Irradiation ◽  
Aryl Halides ◽  
Green Solvent ◽  
Environment Friendly ◽  
Arylboronic Acids

Cu NPs@RGO can effectively catalyze Ullmann C–C homocoupling of aryl halides and arylboronic acids under microwave irradiation in green solvent ionic liquid..

A Phosphine-mediated Synthesis of 2,3,4,5-tetra-substituted Nhydroxypyrroles from α-oximino Ketones and Dialkyl Acetylenedicarboxylates Under Ionic Liquid Green-media

2018 ◽  
Vol 21 (1) ◽  
pp. 14-18
Author(s):  
Ashraf S. Shahvelayati ◽  
Maryam Ghazvini ◽  
Khadijeh Yadollahzadeh ◽  
Akram S. Delbari
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Organic Solvents ◽  
Condensation Reaction ◽  
Reaction Medium ◽  
Sustainable Chemistry ◽  
Polyfunctional Compounds ◽  
High Yields ◽  
Work Up ◽  
Reaction Media

Background: The development of multicomponent reactions (MCRs) in the presence of task-specific ionic liquids (ILs), used not only as environmentally benign reaction media, but also as catalysts, is a new approach that meet with the requirements of sustainable chemistry. In recent years, the use of ionic liquids as a green media for organic synthesis has become a chief study area. This is due to their unique properties such as non-volatility, non-flammability, chemical and thermal stability, immiscibility with both organic compounds and water and recyclability. Ionic liquids are used as environmentally friendly solvents instead of hazardous organic solvents. Objective: We report the condensation reaction between α-oximinoketone and dialkyl acetylene dicarboxylate in the presence of triphenylphosphine to afford substituted pyrroles under ionic liquid conditions in good yields. Result: Densely functionalized pyrroles was easily prepared from reaction of α-oximinoketones, dialkyl acetylene dicarboxylate in the presence of triphenylphosphine in a quantitative yield under ionic liquid conditions at room temperature. Conclusion: In conclusion, ionic liquids are indicated as a useful and novel reaction medium for the selective synthesis of functionalized pyrroles. This reaction medium can replace the use of hazardous organic solvents. Easy work-up, synthesis of polyfunctional compounds, decreased reaction time, having easily available-recyclable ionic liquids, and good to high yields are advantages of present method.

1,3-Dialkylimidazolium Dimethyl Phosphates – Effective Solvents and Catalysts for Condensation Reactions

2014 ◽  
Vol 52 (1-2) ◽  
pp. 41-48
Author(s):  
L. Anteina ◽  
A. Gaidule ◽  
A. Zicmanis
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Malonic Acid ◽  
Condensation Reaction ◽  
Ethyl Cyanoacetate ◽  
Liquid Structure ◽  
Reaction Rates ◽  
Condensation Reactions

Abstract We report the preparation, characterization and exploitation of 1,3-dialkylimidazolium dimethyl phosphates. Condensation reactions of benzaldehyde with ethyl cyanoacetate and with malonic acid were performed in these ionic liquids either in absence or in presence of other catalysts. The effect of ionic liquid structure on the condensation reaction rates and yields was discussed

scholarly journals SBA-15 Modified with Tethered Ionic Liquids Applied in the Esterification of Valeric Acid with Pentanol—Towards Cellulosic Biofuels

2020 ◽  
Vol 1 (2) ◽  
pp. 138-153
Author(s):  
Lisa Mullins ◽  
James A. Sullivan
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Elemental Analysis ◽  
Condensation Reaction ◽  
Valeric Acid ◽  
Esterification Reaction ◽  
Cellulosic Biofuels ◽  
Counter Ion ◽  
Nh3 Adsorption ◽  
Mesoporous Sio2

Two catalysts are prepared by tethering ionic liquid cation components (1-(propyl-3-sulfonate)-3-(3-trimethoxysilylpropyl) imidazolium) with either chloride or sulphate anions, to the surface of a mesoporous SiO2 material through a condensation reaction. These are characterized using elemental analysis, TGA-MS, FTIR (and D-FTIR), TEM, physisorption and NH3 adsorption (TPD and FTIR), and applied in the valeric acid + pentanol esterification reaction to form the sustainable biodiesel Pentyl Valerate. The material containing the sulfate counter-ion was significantly more active than the chloride analogue.

Partition of proteins with extraction in aqueous two-phase system by hydroxyl ammonium-based ionic liquid

2014 ◽  
Vol 6 (12) ◽  
pp. 4067-4076 ◽  
Author(s):  
Jing Chen ◽  
Yuzhi Wang ◽  
Qun Zeng ◽  
Xueqin Ding ◽  
Yanhua Huang
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Phase System ◽  
Two Phase ◽  
Aqueous Two Phase System ◽  
Ammonium Ionic Liquids

A series of hydroxyl ammonium ionic liquids have been designed and synthesized and used for the extraction of proteins.

scholarly journals Solvent-free Knoevenagel reaction catalysed by reusable pyrrolidinium base protic ionic liquids (PyrrILs): synthesis of long-chain alkylidenes

RSC Advances ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 3214-3221 ◽  
Author(s):  
R. C. M. Alves Sobrinho ◽  
P. M. de Oliveira ◽  
C. R. Montes D'Oca ◽  
D. Russowsky ◽  
M. G. Montes D'Oca
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Knoevenagel Condensation ◽  
Condensation Reaction ◽  
Solvent Free ◽  
Knoevenagel Reaction ◽  
Protic Ionic Liquids ◽  
Knoevenagel Condensation Reaction ◽  
Pyrrolidinium Ionic Liquid ◽  
Long Chain

In this work, an efficient and reusable pyrrolidinium ionic liquid (PyrrIL) catalysis system was developed and used in a Knoevenagel condensation reaction of long-chain aldehydes with several 1,3-dicarbonyl compounds.

Synthesis of Medicinally Relevant Scaffolds-Triazoles and Pyrazoles in Green Solvent Ionic Liquids

2021 ◽  
Vol 25 ◽  
Author(s):  
Parmita Phukan ◽  
Diganta Sarma
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Public Sector ◽  
Chemical Industry ◽  
Constant Pressure ◽  
Energy Sources ◽  
Green Solvent ◽  
Efficient Synthesis ◽  
Environment Friendly ◽  
Tremendous Importance

: The use of natural and environment friendly energy sources for betterment of the living society has become an active concern in both government and public sector. Due to this, responsible use of global resources has become a growing concern among people. Similarly, in chemical industry especially in pharmaceutical fields, there is constant pressure in reducing hazardous organic solvents and environmentally detrimental laboratory materials. The use of ionic liquids in efficient synthesis of a wide array of fundamentally important structural motifs has gained tremendous importance in the scientific era. In this review, synthesis of two such medicinally relevant moieties, namely, triazole and pyrazole, in green and sustainable ionic liquid have been discussed.

scholarly journals Bi-SO3H Functionalized Ionic Liquid Based on DABCO: New and Efficient Catalyst for Facile Synthesis of Dihydropyrimidinones

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Firouzeh Nemati ◽  
Sara G. Alizadeh
Keyword(s):  
Ionic Liquid ◽  
Efficient Method ◽  
Condensation Reaction ◽  
Facile Synthesis ◽  
One Pot ◽  
Efficient Catalyst ◽  
Dicarbonyl Compounds ◽  
Functionalized Ionic Liquid ◽  
The One ◽  
Biginelli Condensation

A simple and efficient method for the one-pot Biginelli condensation reaction of aldehydes,β-dicarbonyl compounds, and urea or thiourea employing [DABCO](SO3H)2Cl2as a novel ionic liquid catalyst is described.

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