Silver nanoparticles doped with silver cations, stabilized with maleic acid copolymers: specific structure, antimicrobial properties

2021 ◽  
Author(s):  
Nadezhda Samoilova ◽  
Maria Krayukhina ◽  
Alexander Naumkin ◽  
Nelya Anuchina ◽  
Dmitry Popov

The combined composites containing silver nanoparticles and silver cations were proposed. Water-soluble complexes of silver nanoparticles (AgNPs) stabilized by copolymers of maleic acid with ethylene or N-vinylpyrrolidone were doped with...

2011 ◽  
Vol 10 (04n05) ◽  
pp. 1179-1183
Author(s):  
R. ANITHA ◽  
B. KARTHIKEYAN ◽  
T. PANDIYARAJAN ◽  
S. VIGNESH ◽  
R. ARTHUR JAMES ◽  
...  

Silver nanoparticles are known to have inhibitory antimicrobial properties. In this letter, we report the synthesis of silver nanoparticles by using biocompatible, water soluble polymer through polyol method. Optical absorption spectrum of the prepared particles shows an absorption peak around 433 nm which is because of Surface Plasmon Resonance (SPR) of silver nanoparticles. Fourier transform infrared (FTIR) studies were done to identify the interaction of the nanoparticle and polymer. Transmission Electron Microscopic (TEM) studies confirm that the prepared particles are ~ 100 nm in size. Antifungal activity was studied through standard disk diffusion method. Studies show the prepared particles are potential candidates for the antifungal activity.


Nanoscale ◽  
2021 ◽  
Author(s):  
Ajinkya Girish Nene ◽  
Massimiliano Galluzzi ◽  
Hongrong Luo ◽  
Prakash Somani ◽  
Seeram Ramakrishna ◽  
...  

Owning peculiar oxidative effect, silver cations (Ag+) are well-known for antimicrobial properties and explored as therapeutic agents for biomedical applications. Size control with improved dispersion and stability are the key factors...


2015 ◽  
pp. 75-84 ◽  
Author(s):  
N. A. Samoilova ◽  
M. A. Krayukhina ◽  
D. A. Popov ◽  
N. M. Anuchina ◽  
I. A. Yamskov

Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 317
Author(s):  
HanGoo Kang ◽  
Jinwon Seo ◽  
Eun-Jeong Yang ◽  
In-Hong Choi

Silver nanoparticles (AgNPs) are widely used in various fields because of their antimicrobial properties. However, many studies have reported that AgNPs can be harmful to both microorganisms and humans. Reactive oxygen species (ROS) are a key factor of cytotoxicity of AgNPs in mammalian cells and an important factor in the immune reaction of neutrophils. The immune reactions of neutrophils include the expulsion of webs of DNA surrounded by histones and granular proteins. These webs of DNA are termed neutrophil extracellular traps (NETs). NETs allow neutrophils to catch and destroy pathogens in extracellular spaces. In this study, we investigated how AgNPs stimulate neutrophils, specifically focusing on NETs. Freshly isolated human neutrophils were treated with 5 or 100 nm AgNPs. The 5 nm AgNPs induced NET formation, but the 100 nm AgNPs did not. Subsequently, we investigated the mechanism of AgNP-induced NETs using known inhibitors related to NET formation. AgNP-induced NETs were dependent on ROS, peptidyl arginine deiminase, and neutrophil elastase. The result in this study indicates that treatment of 5 nm AgNPs induce NET formation through histone citrullination by peptidyl arginine deiminase and histone cleavage by neutrophil elastase.


1999 ◽  
Vol 28 (11) ◽  
pp. 1169-1170 ◽  
Author(s):  
Sihai Chen ◽  
Keisaku Kimura

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
M. A. El-Sheikh

The water soluble photoinitiator (PI) 4-(trimethyl ammonium methyl) benzophenone chloride is used for the first time in the synthesis of silver nanoparticles (AgNPs). A new green synthesis method involves using PI/UV system, carboxymethyl starch (CMS), silver nitrate, and water. A mechanism of the reduction of silver ions to AgNPs by PI/UV system as well as by the newly born aldehydic groups was proposed. The synthesis process was assessed by UV-vis spectra and TEM of AgNPs colloidal solution. The highest absorbance was obtained using CMS, PI and AgNO3concentrations of 10 g/L, 1 g/L, and 1 g/L, respectively; 40°C; 60 min; pH 7; and a material : liquor ratio 1 : 20. AgNPs so-obtained were stable in aqueous solution over a period of three weeks at room temperature (~25°C) and have round shape morphology. The sizes of synthesized AgNPs were in the range of 1–21 nm and the highest counts % of these particles were for particles of 6–10 and 1–3 nm, respectively.


2021 ◽  
pp. 130233
Author(s):  
A. Kalam ◽  
A.G. Al-Sehemi ◽  
S. Alrumman ◽  
M.A. Assiri ◽  
A.M. Alfaify ◽  
...  

2021 ◽  
Author(s):  
Jelena S. Katanić Stanković ◽  
◽  
Nikola Srećković ◽  
Vladimir Mihailović

In this study, silver nanoparticles (AgNPs) have been synthesized using the aqueous extract of the aerial parts of B. purpurocaerulea, collected in Serbia. B. purpurocaerulea silver nanoparticles (Bp– AgNPs) synthesis was confirmed using UV-Vis spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR). The biological potential of synthesized Bp-AgNPs was evaluated in vitro using ABTS assay for determining free radical scavenging potential and microdilution method for analysis of antimicrobial properties. Bp-AgNPs showed high antioxidant activity similar to Bp-extract, comparable to BHT. The synthesized nanoparticles exerted remarkable antibacterial effects, with minimal inhibitory concentration (MIC) values below 20 µg/mL. In the case of some bacterial strains, the results of Bp– AgNPs were comparable or similar to standard antibiotic erythromycin. The antifungal activity of Bp– AgNPs was moderate for most of the used strains. Nevertheless, several fungi were resistant to the NPs action, while two tested Penicillium species were extremely sensitive on Bp-AgNPs with MIC lower than 40 µg/mL. The antimicrobial properties of Bp-AgNPs can be useful for the development of new NPs-containing products.


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