scholarly journals Dihydronicotinamide riboside: synthesis from nicotinamide riboside chloride, purification and stability studies

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 21036-21047
Author(s):  
Amin Zarei ◽  
Leila Khazdooz ◽  
Mojtaba Enayati ◽  
Sara Madarshahian ◽  
Timothy J. Wooster ◽  
...  
Keyword(s):  
High Purity ◽  
Stability Studies ◽  
Purification Method ◽  
Nicotinamide Riboside

A convenient and scalable method for synthesis of dihydronicotinamide riboside (NRH) from the commercially available nicotinamide riboside chloride (NRCl) is elaborated as well as a fast purification method that led to high purity NRH.

Next generation purification method for achieving low trace metals in ultra-high purity chemicals

2021 ◽  
Author(s):  
Majid Entezarian ◽  
Mitsuaki Kobayashi ◽  
Yukihisa Okada ◽  
Takaaki Shirai ◽  
Keita Abe ◽  
...  
Keyword(s):  
Trace Metals ◽  
High Purity ◽  
Next Generation ◽  
Purification Method ◽  
Ultra High Purity

scholarly journals Method development for producing thin 14C foils

2020 ◽  
Vol 229 ◽  
pp. 04002
Author(s):  
Matthew Gott ◽  
John Greene ◽  
Igor Pavlovsky ◽  
Richard Fink
Keyword(s):  
High Purity ◽  
Nuclear Physics ◽  
Method Development ◽  
Carbon Oxide ◽  
Carbon Powder ◽  
Robust Method ◽  
Purification Method ◽  
Physics Community ◽  
Thin Foils

Thin, isotopic 14C foils are of great interest to the nuclear physics community as neutron-rich targets. Historically, these foils have been extremely difficult to prepare and an effort is underway to make them readily available. The stock material of 14C available at Argonne contains a number of oxide impurities (SiO2, MgO, and Al2O3), which affect the composition and stability of the fabricated foil. A simple, robust method was developed (using natC as a surrogate) to purify the 14C material while minimizing loss and potential spread of the material. Thin foils were fabricated using the purified carbon, the unpurified carbon/oxide mix, and purchased high-purity carbon powder. SEM and EDS of the resulting foils was performed and the efficacy of this purification method was demonstrated.

scholarly journals Purification Method for Achieving Low Trace Metals in Ultra-High Purity Chemicals

2021 ◽  
Vol 34 (2) ◽  
pp. 205-211
Author(s):  
Mitsuaki Kobayashi ◽  
Yukihisa Okada ◽  
Takaaki Shirai ◽  
Osamu Sawajiri ◽  
Robert Gieger ◽  
...  
Keyword(s):  
Trace Metals ◽  
High Purity ◽  
Purification Method ◽  
Ultra High Purity

Bacillus subtilis Endospores at High Purity and Recovery Yields: Optimization of Growth Conditions and Purification Method

2012 ◽  
Vol 66 (3) ◽  
pp. 279-285 ◽  
Author(s):  
Milene B. Tavares ◽  
Renata D. Souza ◽  
Wilson B. Luiz ◽  
Rafael C. M. Cavalcante ◽  
Caroline Casaroli ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
High Purity ◽  
Growth Conditions ◽  
Purification Method

Iodine doping of substituted μ-carbido iron diphthalocyanines

2011 ◽  
Vol 15 (07n08) ◽  
pp. 748-755 ◽  
Author(s):  
Gloria Zanotti ◽  
Sara Notarantonio ◽  
Anna Maria Paoletti ◽  
Giovanna Pennesi ◽  
Gentilina Rossi
Keyword(s):  
Physicochemical Properties ◽  
General Formula ◽  
High Purity ◽  
Iodine Doping ◽  
Purification Method ◽  
High Purity Grade ◽  
Tert Butyl ◽  
Yield And Purity ◽  
Purity Grade ◽  
Conduction Properties

Hemi and amphi-substituted μ-carbido iron diphthalocyanine having general formula (t- bu ) 4PcFe-C-FePc and (t- bu ) 4PcFe-C-FePc (t- bu )4 have been oxidized with I2. The oxidized compounds have been characterized and their physicochemical properties have been studied; the results obtained lead to assign them the formula [(t- Bu ) 4PcFe-C-FePc ] (I5)0.66 and [[(t- Bu ) 4PcFe ]2 C ]] (I5)0.66 respectively. The conduction properties, related to the role played by the pushing groups inserted in the peripheral macrocycles, are discussed. Moreover, an effective purification method for improving the yield and purity of iron tetra-tert-butyl phthalocyanine is described, the difficulty being able to obtain this precursor with a high purity grade.

scholarly journals Preparation of 6N,7N High-Purity Gallium by Crystallization: Process Optimization

Materials ◽  
2019 ◽  
Vol 12 (16) ◽  
pp. 2549 ◽  
Author(s):  
Jianfeng Hou ◽  
Kefeng Pan ◽  
Xihan Tan
Keyword(s):  
Water Temperature ◽  
Flow Rate ◽  
High Purity ◽  
Crystallization Process ◽  
Cooling Water ◽  
Crystallization Rate ◽  
Purification Method ◽  
Cooling Water Temperature ◽  
Ultra High Purity ◽  
Crystal Seed

In this study, radial crystallization purification method under induction was proposed for preparing 6N,7N ultra-high purity gallium crystal seed. The effect of cooling temperature on the morphology of the crystal seed, as well as the cooling water temperature, flow rate, and the addition amount of crystal seed on the crystallization process was explored, and the best purification process parameters were obtained as follows: temperature of the crystal seed preparation, 278 K; temperature and flow rate of the cooling water, 293 K and 40 L·h−1, respectively; and number of added crystal seed, six. The effects of temperature and flow rate of the cooling water on the crystallization rate were investigated. The crystallization rate decreased linearly with increasing cooling water temperature, but increased exponentially with increasing cooling water flow. The governing equation of the crystallization rate was experimentally determined, and three purification schemes were proposed. When 4N crude gallium was purified by Scheme I, 6N high-purity gallium was obtained, and 7N high-purity gallium was obtained by Schemes II and III. The purity of high-purity gallium prepared by the three Schemes I, II, and III was 99.999987%, 99.9999958%, and 99.9999958%, respectively.

An Improved Purification Method for the Rapid Synthesis of High Purity Fluorobutyrophenone Neuroleptics from Nitro and Chloro Precursors Suitable for PET Study

1994 ◽  
Vol 23 (12) ◽  
pp. 2295-2298 ◽  
Author(s):  
Kazunari Hashizume ◽  
Naoto Hashimoto ◽  
David G. Cork ◽  
Yoshihiro Miyake
Keyword(s):  
High Purity ◽  
Rapid Synthesis ◽  
Purification Method

scholarly journals Synthesis, Stability, and Bioavailability of Nicotinamide Riboside Trioleate Chloride

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 113
Author(s):  
Amin Zarei ◽  
Leila Khazdooz ◽  
Sara Madarshahian ◽  
Mojtaba Enayati ◽  
Imann Mosleh ◽  
...  
Keyword(s):  
Water Activity ◽  
High Water ◽  
Stability Studies ◽  
Intestinal Fluid ◽  
Vitamin B3 ◽  
Simulated Intestinal Fluid ◽  
Nicotinamide Riboside ◽  
Effective Form ◽  
Oil In Water

Nicotinamide riboside chloride (NRCl) is an effective form of vitamin B3. However, it cannot be used in ready-to-drink (RTD) beverages or high-water activity foods because of its intrinsic instability in water. To address this issue, we synthesized nicotinamide riboside trioleate chloride (NRTOCl) as a new hydrophobic nicotinamide riboside (NR) derivative. Contrary to NRCl, NRTOCl is soluble in an oil phase. The results of stability studies showed that NRTOCl was much more stable than NRCl both in water and in oil-in-water emulsions at 25 °C and 35 °C. Finally, we evaluated the bioavailability of NRTOCl by studying its digestibility in simulated intestinal fluid. The results demonstrated that NRTOCl was partially digestible and released NR in the presence of porcine pancreatin in a simulated intestinal fluid. This study showed that NRTOCl has the potential to be used as an NR derivative in ready-to-drink (RTD) beverages and other foods and supplement applications.

Sign in / Sign up

Export Citation Format

Share Document