scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

Soft Matter ◽  
2015 ◽  
Vol 11 (38) ◽  
pp. 7494-7501 ◽  
Author(s):  
Xueyi Chang ◽  
Zhiyu Cheng ◽  
Biye Ren ◽  
Renfeng Dong ◽  
Jun Peng ◽  
...  

A voltage-responsive comb-like superamphiphilic block polymer PEG113-b-PAA30/FTMA was prepared based on the electrostatic interactions of a ferrocenyl surfactant (FTMA) and an oppositely charged poly-(ethylene glycol)-b-poly(acrylic acid) (PEG113-b-PAA30) in aqueous solution.


2019 ◽  
Vol 7 (7) ◽  
pp. 1050-1055 ◽  
Author(s):  
Liangcan He ◽  
Kanglei Pang ◽  
Wenwen Liu ◽  
Yue Tian ◽  
Lin Chang ◽  
...  

Core–shell Au@zeolitic-imidazolate-framework nanocarriers with high drug-loading, controlled drug release properties, and high cancer treatment efficiency.


2020 ◽  
pp. 088532822095259
Author(s):  
Ke Ma ◽  
Yongbin Cheng ◽  
Xinran Wei ◽  
Daijun Chen ◽  
Xiaoli Zhao ◽  
...  

In this work, gold embedded chitosan nanoparticles (Au@CS NPs) were fabricated by a one-pot method. The benzaldehyde-terminated poly[(2-methacryloyloxy) ethyl phosphorylcholine] (PMPC) was applied to modification of the gold doped chitosan nanoparticles. The obtained Au@CS-PMPC NPs had the diameter of 135 nm with a narrow distribution. The size of the Au@CS-PMPC NPs, as well as the size of the embedded gold NPs, might be well-controlled by adjusting the feeding ratio between chitosan and HAuCl4. Furthermore, the Au@CS-PMPC NPs showed increased colloidal stability, high drug loading content, pH-responsive drug release, excellent biocompatibility and bright fluorescence emission. The results demonstrated that Au@CS-PMPC NPs showed a great potential for tumor therapy via the combination advantages of pH-sensitive controlled drug release and cellular fluorescence imaging.


RSC Advances ◽  
2014 ◽  
Vol 4 (36) ◽  
pp. 18604-18607 ◽  
Author(s):  
Xiaojuan Yan ◽  
Xueqin An

A multifunctional polydiacetylene-liposome (PDA-liposome) was prepared by self-assembly, which can be characterized with controlled drug release and fluorescence tracing.


RSC Advances ◽  
2015 ◽  
Vol 5 (7) ◽  
pp. 5269-5276 ◽  
Author(s):  
Qingjian Xing ◽  
Najun Li ◽  
Yang Jiao ◽  
Dongyun Chen ◽  
Jiaying Xu ◽  
...  

The core–shell nanocarrier, based on spiropyran-containing copolymer coated upconversion nanocomposites, was successfully prepared via a facile self-assembly process for NIR-triggered drug release and cancer therapy.


ACS Nano ◽  
2012 ◽  
Vol 6 (4) ◽  
pp. 3327-3338 ◽  
Author(s):  
Yunlu Dai ◽  
Ping’an Ma ◽  
Ziyong Cheng ◽  
Xiaojiao Kang ◽  
Xiao Zhang ◽  
...  

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