Incorporation of poorly soluble drug Cefixime inside the micellar core of conventional and gemini surfactants

2022 ◽  
Author(s):  
Aparna D Saraf ◽  
shweta sharma ◽  
Shilpee Sachar
Keyword(s):  
Cetyl Trimethyl Ammonium Bromide ◽  
Gemini Surfactants ◽  
Ammonium Bromide ◽  
Antibiotic Drug ◽  
Dimethyl Ammonium ◽  
Poorly Soluble ◽  
Dodecyl Trimethyl Ammonium Bromide ◽  
Poorly Soluble Drug ◽  
Cetyl Trimethyl Ammonium ◽  
Micellar Core

This work reports the physicochemical behavior of antibiotic drug, cefixime (CEF) in presence of cetyl trimethyl ammonium bromide (CTAB), dodecyl trimethyl ammonium bromide (DTAB), dodecyl ethyl dimethyl ammonium bromide, (DDAB),...

Activity of Polyphenoloxidase in red Fuji Apples Promoted with Cationic Surfactant – Role of Surfactant Structure

2021 ◽  
Vol 58 (5) ◽  
pp. 383-393
Author(s):  
Maozhang Tian ◽  
Fan Zhang ◽  
Lu Wang ◽  
Xing Dong ◽  
Lifei Zhang ◽  
...  
Keyword(s):  
Gemini Surfactant ◽  
Cetyl Trimethyl Ammonium Bromide ◽  
Gemini Surfactants ◽  
Ammonium Bromide ◽  
Wide Range ◽  
Dimethyl Ammonium ◽  
Dodecyl Trimethyl Ammonium Bromide ◽  
Cetyl Trimethyl Ammonium ◽  
Menten Constant

Abstract In this study, we observed the activity of polyphenoloxidase (PPO) in red Fuji apples in the presence of single-chained surfactants (including cetyl trimethyl ammonium bromide (CTAB), and dodecyl trimethyl ammonium bromide (DTAB)) and gemini surfactants (pentamethylene-α,ω-bis(dodecyl dimethyl ammonium bromide), octamethylene-α,ω-bis(dodecyl dimethyl ammonium bromide, dodecamethylene-α,ω-bis(dodecyl dimethyl ammonium bromide), pentamethylene-α,ω-bis(cetyl dimethyl ammonium bromide), and octamethylene-α,ω-bis(cetyl dimethyl ammonium bromide)). It was found that all these surfactants enhanced the activity of PPO in a wide range of temperature at low content. When PPO was denatured by incubating at high temperature, the surfactants caused reactivation of PPO. Compared to the single-chained surfactants, the gemini surfactants increased PPO activity at a much lower concentration. Moreover, the single-chained surfactant and the gemini surfactant acted together to further increase PPO activity, and the synergistic effect reduced the amount of surfactant used. In addition, the Michaelis-Menten constant for PPO did not change in the presence of the surfactants, suggesting the active site should remain well with the surfactants.

scholarly journals Preparation of Porous Hydroxyapatite Using Cetyl Trimethyl Ammonium Bromide as Surfactant for the Removal of Lead Ions from Aquatic Solutions

Polymers ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1617
Author(s):  
Silviu-Adrian Predoi ◽  
Carmen Steluta Ciobanu ◽  
Mikael Motelica-Heino ◽  
Mariana Carmen Chifiriuc ◽  
Monica Luminita Badea ◽  
...  
Keyword(s):  
Cetyl Trimethyl Ammonium Bromide ◽  
Morphological Changes ◽  
Low Cost ◽  
Lead Ions ◽  
Ammonium Bromide ◽  
Porous Hydroxyapatite ◽  
X Ray ◽  
Composition And Structure ◽  
Cetyl Trimethyl Ammonium ◽  
Co Precipitation

In the present study, a new low-cost bioceramic nanocomposite based on porous hydroxyapatite (HAp) and cetyl trimethyl ammonium bromide (CTAB) as surfactant was successfully obtained by a simple chemical co-precipitation. The composition and structure of the HAp-CTAB were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), scanning electron microscope (SEM) equipped with an energy dispersive X-ray (EDX) spectrometer, and N2 adsorption/desorption analysis. The capacity of HAp-CTAB nanocomposites to remove the lead ions from aqueous solutions was studied by adsorption batch experiments and proved by Langmuir and Freundlich models. The Pb2+ removal efficiency of HAp-CTAB biocomposite was also confirmed by non-destructive ultrasound studies. The cytotoxicity assays showed that the HAp-CTAB nanocomposites did not induce any significant morphological changes of HeLa cells after 24 h of incubation or other toxic effects. Taken together, our results suggests that the obtained porous HAp-CTAB powder could be used for the decontamination of water polluted with heavy metals, such as Pb2+.

Influence of Different Dispersants on the Dispersion Property of Nano-Aluminium Powders

2011 ◽  
Vol 71-78 ◽  
pp. 122-125 ◽  
Author(s):  
Ling Li Song ◽  
Ren Yuan Zhang ◽  
Ling Bo Mao ◽  
Wen Jie Zhu ◽  
Miao Yan Zheng
Keyword(s):  
Sodium Dodecyl Sulfate ◽  
Ultrasonic Vibration ◽  
Cetyl Trimethyl Ammonium Bromide ◽  
Sodium Dodecyl ◽  
Dispersion Property ◽  
Ammonium Bromide ◽  
Aluminum Powders ◽  
Ultrasonic Time ◽  
Dodecyl Sulfate ◽  
Cetyl Trimethyl Ammonium

The influences of dispersant type, supersonic time and concentration on the dispersion property of the nano-aluminium powders in glycol water were systematically studied by using Sodium dodecyl sulfate (SDS)，cetyl trimethyl ammonium bromide (CTAB) and sodium hexa metah posphate（SHMP）as dispersants. During the first stage of the experiments, influences of dispersant type and ultrasonic time with these dispersants were evaluated. The next stage of the study was focused on SHMP concentration. The influence of SHMP concentration was assessed. The results show that with the increasing of ultrasonic time, the dispersion property of nano-aluminum powders first increases and then decreases, and SHMP is the best one. The excellent dispersing condition on the dispersion property of nano-aluminium is: 5g/L SHMP and 50 min ultrasonic vibration.

scholarly journals SYNTHESIS OF COPPER NANOPARTICLES USING ASCORBIC ACID AND CETYL TRIMETHYL AMMONIUM BROMIDE

2018 ◽  
Vol 11 (14) ◽  
pp. 62
Author(s):  
Saurabh Singh ◽  
Bimlesh Kumar ◽  
Narendra Kumar Pandey ◽  
Barinder Kaur ◽  
Arun Kumar ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Copper Nanoparticles ◽  
Cetyl Trimethyl Ammonium Bromide ◽  
Ammonium Bromide ◽  
Distilled Water ◽  
Bromide Solution ◽  
Cetyl Trimethyl Ammonium ◽  
Dialysis Bag ◽  
Spray Dried ◽  
Glass Beaker

Objective: The present study highlights the development of a method to synthesize copper nanoparticles (CuNPs).Methods: CuNPs were developed using 0.01 M copper penta sulfate and 0.11 M of ascorbic acid (AA) and 0.03 M of cetyl trimethyl ammonium bromide solution. The synthesized CuNPs were differentiated through filtration and washed by water (deionized). CuNPs were kept in dialysis bag 70 KD in a 250 mL glass beaker along with distilled water. The assembly was kept on a magnetic stirrer for 24 h at 500 rpm. Then, the dialysis bag containing CuNPs solution was filtered by a filter assembly with 0.2 μm nylon filter. The filtered CuNPs were spray dried with the help of spray drier.Results: The prepared CuNPs were found to be 440 nm with zeta potential of −10 mV and polydispersity index 0.314.Conclusion: The investigation deciphers the promising and material technique to synthesis of CuNPs by methods for synthetic reduction utilizing strategy using AA (0.2 M) and sodium hydroxide (1 M), and Syloid 244FP.

Synthesis of Fe3O4 Nanoparticles Prepared by Various Surfactants and Studying their Characterizations

2008 ◽  
Vol 273-276 ◽  
pp. 22-27 ◽  
Author(s):  
Ali Shokuhfar ◽  
S. Alibeigi ◽  
Mohammad Reza Vaezi ◽  
Sayed Khatiboleslam Sadrnezhaad
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Cetyl Trimethyl Ammonium Bromide ◽  
Precipitation Method ◽  
Ammonium Bromide ◽  
X Ray Diffraction ◽  
Mixed Salt ◽  
Magnetite Fe3o4 ◽  
Cetyl Trimethyl Ammonium ◽  
Size And Morphology ◽  
Co Precipitation

Magnetite (Fe3O4) nanoparticles were prepared simply by the reverse co-precipitation method from the solution of ferrous/ferric mixed salt in the presence of cationic surfactant (cetyl trimethyl ammonium bromide, CTAB) and nonionic surfactant (Polyethylene glycol, PEG) in two concentrations. Meanwhile, Fe3O4 nanoparticles without surfactant are also synthesized under the same condition for comparison. In addition via the reverse co-precipitation method, the pH which is an important factor in synthesis of magnetite was controlled at high values easily. The experimental results reveal that addition of surfactants affected on the size and morphology of the nanoparticles based on the X-ray diffraction (XRD) and scanning electron microscope (SEM) characterizations.

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