scholarly journals A day in the life of a Clinical Scientist

2018 ◽  
Vol 40 (1) ◽  
pp. 40-41

Allan Dunlop graduated with a BSc in Medical Biochemistry from the University of Glasgow, where he subsequently completed his PhD. He then worked as a postdoctoral researcher in the area of cAMP phosphodiesterases and cellular signalling and undertook training as a Clinical Scientist in the department of Biochemistry at Aberdeen Royal Infirmary. Allan is currently employed as a Principal Clinical Scientist in the department of Clinical Biochemistry at the Queen Elizabeth University Hospital in Glasgow. Lorenza Giannella (Training Manager, Biochemical Society) spoke to him about his work.

2019 ◽  
Vol 41 (6) ◽  
pp. 46-47

David Smith is a Reader in Biochemistry at Sheffield Hallam University and a National Teaching Fellow. He is a Senior Fellow of the Higher Education Academy and has received the Sheffield Hallam Vice Chancellor's Award for Inspirational Teaching, as well as the Royal Society of Biology Higher Education Bioscience Teacher of the Year Award 2019. David has been an active researcher in the field of biosciences for over 20 years, focusing on the molecular basis of neurodegeneration in diseases such as Alzheimer's and Parkinson's. He completed a PhD at the University of Leeds, before working as a postdoctoral researcher first at the University of Melbourne and then at the University of Leeds. Lorenza Giannella (Training Manager, Biochemical Society) spoke with him about his work.


2021 ◽  
Vol 134 (3) ◽  

ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Miguel Burgos is first author on ‘The p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis’, published in JCS. Miguel conducted the research described in this article while a postdoctoral researcher in Olivier Mignen's lab at the Université de Brest, Brest, France. He is now a senior postdoctoral researcher and Associate Professor in the lab of Alberto Ocaña at Albacete University Hospital and the University of Castilla-La Mancha, Spain, investigating the pathophysiology of calcium homeostasis.


VASA ◽  
2004 ◽  
Vol 33 (2) ◽  
pp. 78-81 ◽  
Author(s):  
Thalhammer ◽  
Aschwanden ◽  
Jeanneret ◽  
Labs ◽  
Jäger

Background: Haemostatic puncture closure devices for rapid and effective hemostasis after arterial catheterisation are a comfortable alternative to manual compression. Implanting a collagen plug against the vessel wall may become responsible for other kind of vascular injuries i.e. thrombotic or stenotic lesions and peripheral embolisation. The aim of this paper is to report our clinically relevant vascular complications after Angio-Seal® and to discuss the results in the light of the current literature. Patients and methods: We report the symptomatic vascular complications in 17 of 7376 patients undergoing diagnostic or therapeutic catheterisation between May 2000 and March 2003 at the University Hospital Basel. Results: Most patients presented with ischaemic symptoms, arterial stenoses or occlusions and thrombotic lesions (n = 14), whereas pseudoaneurysms were extremely rare (n = 3). Most patients with ischaemic lesions underwent vascular surgery and all patients with a pseudoaneurysm were successfully treated by ultrasound-guided compression. Conclusions: Severe vascular complications after Angio-Seal® are rare, consistent with the current literature. There may be a shift from pseudoaneurysms to ischaemic lesions.


1993 ◽  
Vol 32 (05) ◽  
pp. 365-372 ◽  
Author(s):  
T. Timmeis ◽  
J. H. van Bemmel ◽  
E. M. van Mulligen

AbstractResults are presented of the user evaluation of an integrated medical workstation for support of clinical research. Twenty-seven users were recruited from medical and scientific staff of the University Hospital Dijkzigt, the Faculty of Medicine of the Erasmus University Rotterdam, and from other Dutch medical institutions; and all were given a written, self-contained tutorial. Subsequently, an experiment was done in which six clinical data analysis problems had to be solved and an evaluation form was filled out. The aim of this user evaluation was to obtain insight in the benefits of integration for support of clinical data analysis for clinicians and biomedical researchers. The problems were divided into two sets, with gradually more complex problems. In the first set users were guided in a stepwise fashion to solve the problems. In the second set each stepwise problem had an open counterpart. During the evaluation, the workstation continuously recorded the user’s actions. From these results significant differences became apparent between clinicians and non-clinicians for the correctness (means 54% and 81%, respectively, p = 0.04), completeness (means 64% and 88%, respectively, p = 0.01), and number of problems solved (means 67% and 90%, respectively, p = 0.02). These differences were absent for the stepwise problems. Physicians tend to skip more problems than biomedical researchers. No statistically significant differences were found between users with and without clinical data analysis experience, for correctness (means 74% and 72%, respectively, p = 0.95), and completeness (means 82% and 79%, respectively, p = 0.40). It appeared that various clinical research problems can be solved easily with support of the workstation; the results of this experiment can be used as guidance for the development of the successor of this prototype workstation and serve as a reference for the assessment of next versions.


1995 ◽  
Vol 34 (01/02) ◽  
pp. 75-78 ◽  
Author(s):  
R. D. Appel ◽  
O. Golaz ◽  
Ch. Pasquali ◽  
J.-C. Sanchez ◽  
A. Bairoch ◽  
...  

Abstract:The sharing of knowledge worldwide using hypermedia facilities and fast communication protocols (i.e., Mosaic and World Wide Web) provides a growth capacity with tremendous versatility and efficacy. The example of ExPASy, a molecular biology server developed at the University Hospital of Geneva, is striking. ExPASy provides hypermedia facilities to browse through several up-to-date biological and medical databases around the world and to link information from protein maps to genome information and diseases. Its extensive access is open through World Wide Web. Its concept could be extended to patient data including texts, laboratory data, relevant literature findings, sounds, images and movies. A new hypermedia culture is spreading very rapidly where the international fast transmission of documents is the central element. It is part of the emerging new “information society”.


2019 ◽  
Author(s):  
M Stättermayer ◽  
F Riedl ◽  
S Bernhofer ◽  
A Stättermayer ◽  
A Mayer ◽  
...  

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