Relation of the Extracellular [Bicarbonate]/[Chloride] Ratio to Erythrocyte Sodium Content: A Possible New Control System
Keyword(s):
1. Erythrocytes were incubated in buffers with different [bicarbonate]/[chloride] ratios. 2. The erythrocyte sodium content was higher in buffers with higher [bicarbonate]/ [chloride] ratios. 3. The rise in erythrocyte sodium concentration with increase in [bicarbonate]/[chloride] ratio was independent of the effects of ouabain and ouabain plus ethacrynic acid. Primaquine-induced changes in membrane permeability, ATP depletion by starvation and the use of potassium-free buffers did not change the effect. 4. The results may demonstrate a system which either increases the permeability of erythrocytes to sodium or regulates the sodium content of erythrocytes by a carrier system which is independent of ATP.
1994 ◽
Vol 76
(3)
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pp. 1156-1165
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2019 ◽
Vol 12
(2)
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pp. 122-129
1977 ◽
Vol 91
(2)
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pp. 317-321
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2007 ◽
Vol 2007
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pp. 1-5
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2021 ◽
pp. 125-133
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1965 ◽
Vol 209
(5)
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pp. 955-960
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2010 ◽
Vol 45
(6)
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pp. 601-608
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