Sex-Specific Prevalence, Demographic Characteristics, and Risk Factors of Tinnitus in the Hispanic Community Health Study/Study of Latinos

2022 ◽  
pp. 1-13
Author(s):  
Michelle L. Arnold ◽  
Sumitrajit Dhar ◽  
David J. Lee ◽  
Krista M. Perreira ◽  
Daniel Pupo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Community Health ◽  
Noise Exposure ◽  
Survey Methodology ◽  
Smoking History ◽  
Chronic Tinnitus ◽  
Health Study ◽  
Lifestyle Modifications ◽  
Cross Sectional ◽  
Hispanic Community

Purpose: The aim of this study was to determine the prevalence of any and chronic tinnitus among female and male individuals from varied Hispanic/Latino backgrounds and to estimate associations between risk factors for chronic tinnitus. Method: Our analysis used cross-sectional baseline data collected from 2008 to 2011 from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Prevalence estimates and multivariable logistic regression were conducted using survey methodology. Participants included 15,768 adults (8,229 women and 7,539 men) aged 18–76 years. The primary outcome of interest was chronic tinnitus, defined as self-reported tinnitus lasting ≥ 5 min at a time and at least once per week. We hypothesized that after adjusting for covariates, the risk factors of depressed and anxious symptoms, smoking history, hypertension, and noise exposure history would be associated with higher odds of chronic tinnitus. Results: Unstratified prevalence for any tinnitus was 32.9%, and for chronic tinnitus, it was 12.1%. Sex-stratified results demonstrated that 2,995 female individuals (36.4%) and 2,187 male individuals (29.0%) reported any tinnitus, and of these, 1,043 female individuals (12.7%) and 870 male individuals (11.5%) reported chronic tinnitus. In the fully adjusted model, depressed and anxious symptoms as well as recreational noise exposure were associated with higher odds of chronic tinnitus in female individuals (odds ratios [ ORs ] = 1.06, confidence interval [CI; 1.04, 1.07]; 1.02, CI [1.01, 1.04]; and 1.40, CI [1.20, 1.62]) and in male individuals ( OR s = 1.06, CI [1.03, 1.08]; 1.05, CI [1.02, 1.08]; and 1.30, CI [1.05, 1.65]). Current smoking was a risk factor for chronic tinnitus in male individuals ( OR = 1.53, CI [1.16, 2.02]). Conclusions: Prevalence of any and chronic tinnitus in the HCHS/SOL baseline cohort is higher than that reported in previous studies, particularly among female individuals. Understanding risk factors associated with tinnitus is important for the development of culturally and linguistically appropriate public health programs that consider sex differences and promote lifestyle modifications known to lower the odds of experiencing tinnitus.

scholarly journals Gut microbiome composition in the Hispanic Community Health Study/Study of Latinos is shaped by geographic relocation, environmental factors, and obesity

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Robert C. Kaplan ◽  
Zheng Wang ◽  
Mykhaylo Usyk ◽  
Daniela Sotres-Alvarez ◽  
Martha L. Daviglus ◽  
...  
Keyword(s):  
Community Health ◽  
Gut Microbiome ◽  
Alpha Diversity ◽  
Amplicon Sequencing ◽  
Shannon Index ◽  
Health Study ◽  
Rrna Gene ◽  
Cross Sectional ◽  
Hispanic Community ◽  
The Usa

Abstract Background Hispanics living in the USA may have unrecognized potential birthplace and lifestyle influences on the gut microbiome. We report a cross-sectional analysis of 1674 participants from four centers of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), aged 18 to 74 years old at recruitment. Results Amplicon sequencing of 16S rRNA gene V4 and fungal ITS1 fragments from self-collected stool samples indicate that the host microbiome is determined by sociodemographic and migration-related variables. Those who relocate from Latin America to the USA at an early age have reductions in Prevotella to Bacteroides ratios that persist across the life course. Shannon index of alpha diversity in fungi and bacteria is low in those who relocate to the USA in early life. In contrast, those who relocate to the USA during adulthood, over 45 years old, have high bacterial and fungal diversity and high Prevotella to Bacteroides ratios, compared to USA-born and childhood arrivals. Low bacterial diversity is associated in turn with obesity. Contrasting with prior studies, our study of the Latino population shows increasing Prevotella to Bacteroides ratio with greater obesity. Taxa within Acidaminococcus, Megasphaera, Ruminococcaceae, Coriobacteriaceae, Clostridiales, Christensenellaceae, YS2 (Cyanobacteria), and Victivallaceae are significantly associated with both obesity and earlier exposure to the USA, while Oscillospira and Anaerotruncus show paradoxical associations with both obesity and late-life introduction to the USA. Conclusions Our analysis of the gut microbiome of Latinos demonstrates unique features that might be responsible for health disparities affecting Hispanics living in the USA.

scholarly journals Cross-sectional and prospective associations between sleep regularity and metabolic health in the Hispanic Community Health Study/Study of Latinos

SLEEP ◽  
2020 ◽  
Author(s):  
Josef Fritz ◽  
Andrew J K Phillips ◽  
Larissa C Hunt ◽  
Akram Imam ◽  
Kathryn J Reid ◽  
...  
Keyword(s):  
Community Health ◽  
Cell Function ◽  
Diabetes Risk ◽  
Health Study ◽  
Diabetes Incidence ◽  
Antidiabetic Medication ◽  
Cross Sectional ◽  
Hispanic Community ◽  
Changes Over Time ◽  
Over Time

Abstract Study Objectives Sleep is an emergent, multi-dimensional risk factor for diabetes. Sleep duration, timing, quality, and insomnia have been associated with diabetes risk and glycemic biomarkers, but the role of sleep regularity in the development of metabolic disorders is less clear. Methods We analyzed data from 2107 adults, aged 19–64 years, from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos, followed over a mean of 5.7 years. Multivariable-adjusted complex survey regression methods were used to model cross-sectional and prospective associations between the sleep regularity index (SRI) in quartiles (Q1-least regular, Q4-most regular) and diabetes (either laboratory-confirmed or self-reported antidiabetic medication use), baseline levels of insulin resistance (HOMA-IR), beta-cell function (HOMA-β), hemoglobin A1c (HbA1c), and their changes over time. Results Cross-sectionally, lower SRI was associated with higher odds of diabetes (odds ratio [OR]Q1 vs. Q4 = 1.64, 95% CI: 0.98–2.74, ORQ2 vs. Q4 = 1.12, 95% CI: 0.70–1.81, ORQ3 vs. Q4 = 1.00, 95% CI: 0.62–1.62, ptrend = 0.023). The SRI effect was more pronounced in older (aged ≥ 45 years) adults (ORQ1 vs. Q4 = 1.88, 95% CI: 1.14–3.12, pinteraction = 0.060) compared to younger ones. No statistically significant associations were found between SRI and diabetes incidence, as well as baseline HOMA-IR, HOMA-β, and HbA1c values, or their changes over time among adults not taking antidiabetic medication. Conclusions Our results suggest that sleep regularity represents another sleep dimension relevant for diabetes risk. Further research is needed to elucidate the relative contribution of sleep regularity to metabolic dysregulation and pathophysiology.

scholarly journals Risk factors for hearing impairment among adults with diabetes: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

2016 ◽  
Vol 6 ◽  
pp. 15-22 ◽  
Author(s):  
Kathleen E. Bainbridge ◽  
Catherine C. Cowie ◽  
Franklyn Gonzalez ◽  
Howard J. Hoffman ◽  
Elizabeth Dinces ◽  
...  
Keyword(s):  
Risk Factors ◽  
Community Health ◽  
Hearing Impairment ◽  
Health Study ◽  
Hispanic Community

scholarly journals Variations of dietary intake by glycemic status and Hispanic/Latino heritage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

2018 ◽  
Vol 6 (1) ◽  
pp. e000486 ◽  
Author(s):  
Sarah S Casagrande ◽  
Daniela Sotres-Alvarez ◽  
Larissa Avilés-Santa ◽  
Matthew J O’Brien ◽  
Cristina Palacios ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Community Health ◽  
Energy Intake ◽  
Sodium Intake ◽  
Health Study ◽  
Fiber Intake ◽  
Glycemic Status ◽  
Cross Sectional ◽  
Hispanic Community ◽  
Diagnosed Diabetes

ObjectiveA healthy diet is important for diabetes prevention and control; however, few studies have assessed dietary intake among US Hispanics/Latinos, a diverse population with a significant burden of diabetes. To address this gap in the literature, we determined intake of energy, macro/micronutrients, and vitamin supplements among Hispanics/Latinos by glycemic status and heritage.Research design and methodsCross-sectional study of adults aged 18–74 years from the Hispanic Community Health Study/Study of Latinos (2008–2011) with complete baseline data on glycemic status and two 24-hour dietary recalls (n=13 089). Age-adjusted and sex-adjusted and multivariable-adjusted measures of intake were determined by glycemic status and heritage.ResultsMean age-adjusted and sex-adjusted energy intake was significantly lower among Hispanics/Latinos with diagnosed diabetes compared with those with normal glycemic status (1665 vs 1873 kcal, P<0.001). Fiber intake was higher among those with diagnosed diabetes versus normal glycemic status (P<0.01). Among those with diagnosed diabetes, energy intake was highest among those with Cuban heritage compared with most other heritage groups (P<0.01 for all, except Mexicans), but there was no difference after additional adjustment. Fiber intake was significantly lower for those of Cuban heritage (vs Dominican, Central American, and Mexican), and sodium intake was significantly higher (vs all other heritage groups) (P<0.01 for all); findings were null after additional adjustment. There was no difference in supplemental intake of vitamin D, calcium, magnesium, or potassium by glycemic status.ConclusionsAs part of the care of Hispanics/Latinos with diabetes, attention should be made to fiber and sodium consumption.

scholarly journals Gestational diabetes and cardiovascular risk factors and disease in U.S. Hispanics/Latinas in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

2018 ◽  
Vol 59 (5) ◽  
pp. 481-495 ◽  
Author(s):  
Marisa J Perera ◽  
Samantha A Reina ◽  
Tali Elfassy ◽  
JoNell E Potter ◽  
Daniela Sotres Alvarez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Gestational Diabetes ◽  
Community Health ◽  
Cardiovascular Risk Factors ◽  
Health Study ◽  
Hispanic Community

Abstract MP59: Serum Sphingolipids and Incident Diabetes in US Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Jin Choul Chai ◽  
Guochong Chen ◽  
Bing Yu ◽  
Megan Grove ◽  
Amanda M Fretts ◽  
...  
Keyword(s):  
Risk Factors ◽  
Community Health ◽  
Incident Diabetes ◽  
Health Study ◽  
Central Adiposity ◽  
Modest Improvement ◽  
Chemical Structures ◽  
Net Reclassification Improvement ◽  
Hispanic Community ◽  
Traditional Risk Factors

Introduction: Genetic or pharmacological inhibition of sphingolipid synthases prevented diabetes in animal studies. Scanty of cohort studies that examined circulating sphingolipids and incident diabetes yielded disparate findings. Hypothesis: Specific sphingolipids are associated with elevated risk of diabetes beyond traditional risk factors. Methods: Untargeted metabolomics profiling was performed using fasting serum samples collected from 2010 adult participants of the Hispanic Community Health Study/Study of Latinos, who were free of diabetes and other major chronic diseases at baseline (2008 to 2011). A total of 43 sphingolipids were quantified and 6 sphingolipid scores were derived considering subclasses and chemical structures. Survey Poisson regressions were applied to estimate relative risk (RR) and 95% confidence interval (CI) of incident diabetes associated with individual sphingolipids and the scores. Results: Over ~6 years of follow-up, 224 incident diabetes cases were identified using the ADA criteria. After adjustment for socioeconomic and lifestyle factors, 8 sphingolipids were associated with higher risk of diabetes significantly at the FDR-adjusted level ( Figure ). After further adjusting for general and central adiposity, blood pressure, CRP, HDL cholesterol, and triglycerides, only associations for three saturated sphingomyelins (SMs),36:0 (RR =1.41 [95% CI 1.17-1.69]), 38:0 (RR =1.32 [1.11-1.56]), and d18:0/22:0 (RR =1.45 [1.24-1.71]) remained. Of the 6 scores, only a score comprising 5 saturated SMs was associated with higher risk of diabetes (RR =1.31 [1.12-1.53]) after the full adjustment. An addition of the saturated SM score to the full model including traditional risk factor lead to a modest improvement in diabetes risk classification (net reclassification improvement = 22.0%; 95% CI: 7.8%-36.1%). Conclusions: Our findings suggest that a cluster of saturated SMs may be associated with higher risk of diabetes beyond traditional risk factors in US Hispanics/Latinos.

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