Acoustic Characteristics of Stop Consonants in Children with Fetal Alcohol Syndrome

2015 ◽  
Vol 25 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Christopher Bolinger ◽  
James Dembowski
Keyword(s):  
Motor Control ◽  
Fetal Alcohol Syndrome ◽  
Voice Onset Time ◽  
Prenatal Alcohol Exposure ◽  
Onset Time ◽  
Stop Consonant ◽  
Alcohol Exposure ◽  
Control Group ◽  
Fetal Alcohol ◽  
Oral Motor

Speech of children with fetal alcohol syndrome (FAS) has been little studied compared to language. Becker, Warr-Leeper, and Leeper (1990), found a relationship between prenatal alcohol exposure, oral motor control, and speech articulation. Behavioral tests suggest deficits in focal oral motor control specific to children with FAS (Bolinger & Dembowski, 2010). The current project extends that investigation through acoustic measures. Peak and mean frequencies of stop consonant releases were used to infer control of place of articulation. Voice onset time (VOT) was used to infer articulatory-laryngeal coordination. Preliminary measures on 3 experimental speakers and 2 matched neurotypical controls suggest higher stop consonant frequencies in the experimental group, with a poorer distinction between alveolar and velar stops than in the control group. Voiced VOT values were significantly longer for FAS children than for controls. Mean voiceless VOTs were similar across groups, but substantially more variable for the FAS children. Values may be interpreted as acoustic evidence for specific speech motor control deficits in FAS children relative to matched neurotypical children.

Synthesizing Animal and Human Studies of Prenatal Alcohol Exposure

2001 ◽  
Vol 7 (5) ◽  
pp. 648-649 ◽  
Author(s):  
Paul D. Connor
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Behavioral Disturbances ◽  
Quarter Century ◽  
Prenatal Alcohol ◽  
Primary Focus ◽  
Maternal Alcohol Abuse ◽  
The Impact

The primary focus of this volume is on the impact of alcohol on brain development. It is a perfect example of how research on both animals and humans can interact to produce very important findings. In the case of prenatal alcohol exposure, dialogue between animal and human researchers has proved to be very profitable for both lines of research. Initial observations by human researchers identified a syndrome of facial stigmata, physical malformations, and early behavioral disturbances that was related to maternal alcohol abuse during pregnancy. They gave this syndrome the name Fetal Alcohol Syndrome. However, human researchers were unable to state unequivocally that prenatal alcohol exposure was teratogenic to the fetus. Thus, they turned to animal researchers who were able to model Fetal Alcohol Syndrome in a variety of animals and to confirm the teratogenicity of alcohol on the developing fetus. The quarter century of studies of the damage caused by prenatal alcohol exposure is replete with such interactions between these two groups of researchers. Without the input and pioneering studies of animal researchers on the effects of prenatal alcohol exposure, human researchers would have much less understanding of the damage caused by alcohol exposure in utero or insights into possible treatment or remediation strategies for those damaged by alcohol exposure.

Comparison of Motor Delays in Young Children With Fetal Alcohol Syndrome to Those With Prenatal Alcohol Exposure and With No Prenatal Alcohol Exposure

2006 ◽  
Vol 30 (12) ◽  
pp. 2037-2045 ◽  
Author(s):  
Wendy O. Kalberg ◽  
Beth Provost ◽  
Sean J. Tollison ◽  
Barbara G. Tabachnick ◽  
Luther K. Robinson ◽  
...  
Keyword(s):  
Young Children ◽  
Fetal Alcohol Syndrome ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Prenatal Alcohol

Heavy prenatal alcohol exposure with or without physical features of fetal alcohol syndrome leads to IQ deficits

1997 ◽  
Vol 131 (5) ◽  
pp. 718-721 ◽  
Author(s):  
Sarah N. Mattson ◽  
Edward P. Riley ◽  
Laura Gramling ◽  
Dean C. Delis ◽  
Kenneth Lyons Jones
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Prenatal Alcohol ◽  
Physical Features

Fetal Alcohol Syndrome

2003 ◽  
Vol 22 (3) ◽  
pp. 63-70 ◽  
Author(s):  
Martha Wilson Jones ◽  
W. Thomas Bass
Keyword(s):  
Mental Retardation ◽  
Public Education ◽  
Fetal Alcohol Syndrome ◽  
Birth Defects ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
The World ◽  
Prenatal Alcohol ◽  
Pregnant Mothers

FETAL ALCOHOL SYNDROME (FAS) is the leading known cause of mental retardation and birth defects in the world.1,2 It is caused by in utero exposure to alcohol and is entirely preventable. Because alcohol is a known teratogen and the damage done to a fetus by alcohol exposure is permanent, public education about the dangers of prenatal alcohol exposure has been extensive. Nevertheless, alcohol is a widely accepted and legal social drug, and many pregnant mothers continue to drink it while pregnant. Other mothers drink before they are aware of their pregnancy. This column provides information regarding the incidence of FAS, its etiology, spectrum of effects, and diagnosis. We also discuss potential disabilities that these infants may face as they grow and suggest how to work effectively with the families.

scholarly journals A brief overview of fetal alcohol syndrome for health professionals

2021 ◽  
Vol 30 (15) ◽  
pp. 890-893
Author(s):  
Peter Kruithof ◽  
Sasha Ban
Keyword(s):  
Fetal Alcohol Syndrome ◽  
Fetal Alcohol Spectrum Disorders ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Fetal Alcohol ◽  
Health And Social Care ◽  
The Family ◽  
Spectrum Disorders ◽  
The Individual ◽  
Fetal Alcohol Spectrum

Fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorders (FASDs) are caused by prenatal alcohol exposure (PAE). They cause epigenetic changes, permanent neurodevelopmental deficits, and anomalies in growth and facial structure. This article enforces the need for health and social care professionals to have a greater understanding and awareness of how FAS and FASD may impact on the individual, the family and the community, to enable them to provide the most effective preventive and supportive care possible.

Phonetic feature size in second language acquisition: Examining VOT in voiceless and voiced stops

2021 ◽  
pp. 026765832110089
Author(s):  
Daniel J Olson
Keyword(s):  
Second Language ◽  
Second Language Acquisition ◽  
Voice Onset Time ◽  
Onset Time ◽  
Stop Consonant ◽  
Acoustic Similarity ◽  
Stop Consonants ◽  
Voiceless Stop ◽  
English Speaking ◽  
Underlying Mechanisms

Featural approaches to second language phonetic acquisition posit that the development of new phonetic norms relies on sub-phonemic features, expressed through a constellation of articulatory gestures and their corresponding acoustic cues, which may be shared across multiple phonemes. Within featural approaches, largely supported by research in speech perception, debate remains as to the fundamental scope or ‘size’ of featural units. The current study examines potential featural relationships between voiceless and voiced stop consonants, as expressed through the voice onset time cue. Native English-speaking learners of Spanish received targeted training on Spanish voiceless stop consonant production through a visual feedback paradigm. Analysis focused on the change in voice onset time, for both voiceless (i.e. trained) and voiced (i.e. non-trained) phonemes, across the pretest, posttest, and delayed posttest. The results demonstrated a significant improvement (i.e. reduction) in voice onset time for voiceless stops, which were subject to the training paradigm. In contrast, there was no significant change in the non-trained voiced stop consonants. These results suggest a limited featural relationship, with independent voice onset time (VOT) cues for voiceless and voices phonemes. Possible underlying mechanisms that limit feature generalization in second language (L2) phonetic production, including gestural considerations and acoustic similarity, are discussed.

scholarly journals VOICE ONSET TIME IN MULTILINGUAL SPEAKERS: ITALIAN HERITAGE SPEAKERS IN GERMANY WITH L3 ENGLISH

2021 ◽  
pp. 1-25
Author(s):  
Miriam Geiss ◽  
Sonja Gumbsheimer ◽  
Anika Lloyd-Smith ◽  
Svenja Schmid ◽  
Tanja Kupisch
Keyword(s):  
Heritage Language ◽  
Voice Onset Time ◽  
Onset Time ◽  
English Speakers ◽  
Control Group ◽  
Heritage Speakers ◽  
Third Language ◽  
Bilingual Advantage ◽  
L3 Acquisition ◽  
Crosslinguistic Influence

Abstract This study brings together two previously largely independent fields of multilingual language acquisition: heritage language and third language (L3) acquisition. We investigate the production of fortis and lenis stops in semi-naturalistic speech in the three languages of 20 heritage speakers (HSs) of Italian with German as a majority language and English as L3. The study aims to identify the extent to which the HSs produce distinct values across all three languages, or whether crosslinguistic influence (CLI) occurs. To this end, we compare the HSs’ voice onset time (VOT) values with those of L2 English speakers from Italy and Germany. The language triad exhibits overlapping and distinct VOT realizations, making VOT a potentially vulnerable category. Results indicate CLI from German into Italian, although a systemic difference is maintained. When speaking English, the HSs show an advantage over the Italian L2 control group, with less prevoicing and longer fortis stops, indicating a specific bilingual advantage.

scholarly journals An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Manjot S. Virdee ◽  
Nipun Saini ◽  
Colin D. Kay ◽  
Andrew P. Neilson ◽  
Sze Ting Cecilia Kwan ◽  
...  
Keyword(s):  
Phenolic Acids ◽  
Fetal Liver ◽  
Prenatal Alcohol Exposure ◽  
Fetal Brain ◽  
Principal Component ◽  
Alcohol Exposure ◽  
Maternal Plasma ◽  
Cognitive Disability ◽  
Fetal Alcohol ◽  
Network Analyses

AbstractPrenatal alcohol exposure (PAE) causes permanent cognitive disability. The enteric microbiome generates microbial-dependent products (MDPs) that may contribute to disorders including autism, depression, and anxiety; it is unknown whether similar alterations occur in PAE. Using a mouse PAE model, we performed untargeted metabolome analyses upon the maternal–fetal dyad at gestational day 17.5. Hierarchical clustering by principal component analysis and Pearson’s correlation of maternal plasma (813 metabolites) both identified MDPs as significant predictors for PAE. The majority were phenolic acids enriched in PAE. Correlational network analyses revealed that alcohol altered plasma MDP-metabolite relationships, and alcohol-exposed maternal plasma was characterized by a subnetwork dominated by phenolic acids. Twenty-nine MDPs were detected in fetal liver and sixteen in fetal brain, where their impact is unknown. Several of these, including 4-ethylphenylsulfate, oxindole, indolepropionate, p-cresol sulfate, catechol sulfate, and salicylate, are implicated in other neurological disorders. We conclude that MDPs constitute a characteristic biosignature that distinguishes PAE. These MDPs are abundant in human plasma, where they influence physiology and disease. Their altered abundance here may reflect alcohol’s known effects on microbiota composition and gut permeability. We propose that the maternal microbiome and its MDPs are a previously unrecognized influence upon the pathologies that typify PAE.

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