scholarly journals CT and MRI Imaging Features and Grades of Liver Iron Deposition

2019 ◽  
Vol 26 ◽  
pp. 02003
Author(s):  
Qianwen Huang ◽  
Simin Lin ◽  
Shaoyin Duan
Keyword(s):  
False Negative ◽  
Laboratory Data ◽  
Iron Deposition ◽  
Normal Density ◽  
Imaging Features ◽  
Mri Imaging ◽  
Liver Iron ◽  
Ct Value ◽  
Significant Difference ◽  
Ct And Mri

CT and MRI imaging features and grades of liver iron deposition（LID）were discussed and evaluated in clinical application.The imaging and laboratory data of 20 patients with LID were analyzed retrospectively. CT value of liver were measured and MR signal intensity ratio of muscle/liver calculated.A new imaging grade of LID were made with CT and MR, and the grade correlation was analyzed between CT, MR and SF. All of 20 patients with LID, 19 cases were CT examination, their CT value ranging of liver were from 55HU to 116HU, of which more than 72HU were in 7 cases and 72HU or less in 12. 14 cases were MR examination with the low signal of liver, and the inverse phase signal of T1WI was higher than that of the positive phase. There were no significant difference among the grade of CT, T1WI, T2WI and SF (P>0.05), and there were the positive correlation of grade between CT, T1WI, T2WI and SF (rs=0.803,0.847,0.677 respectively), and of values between CT, T1WI SIR, T2WI SIR and SF(rs=0.454, 0.538, 0.811 respectively). CT can show the LID with high-density, but the mild LID can be with normal density, which is the false negative. MRI can show LID with low-signal, of which T2WI is the lower than T1WI, it is beneficial to diagnose the early LID. Grades of CT and MR have good consistent with that of SF, and can reflect the severity of LID, particularly that of MR-T1WI grading.

scholarly journals The Peritumoral Hypointense Rim Around Hepatocellular Carcinoma on T2*-Weighted Magnetic Resonance Imaging: Radiologic-Pathologic Correlation

2020 ◽  
Author(s):  
Yoshinori Tsukahara ◽  
Yukinori Okajima ◽  
Akira Yamada ◽  
Masanobu Momose ◽  
Takeshi Uehara ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Optical Density ◽  
Quantitative Methods ◽  
Iron Deposition ◽  
Fibrous Capsule ◽  
Blue Staining ◽  
Liver Iron ◽  
Significant Difference ◽  
Weighted Magnetic Resonance Imaging ◽  
Histopathologic Findings

Abstract BackgroundThe peritumoral hypointense rim (PTHR) is sometimes observed around hepatocellular carcinoma (HCC) on T2*-weighted images (T2*WIs). We aimed to investigate the association between the PTHR and histopathologic findings on T2*WIs.MethodsWe assessed the presence of a PTHR on T2*WIs in 39 pathologically proven HCCs from April 2012 to December 2013. Prussian blue staining was performed, and iron deposition was evaluated by semiquantitative and quantitative methods. Optical density was used in the quantitative methods. The associations between a PTHR on T2*WI and histopathologic peritumoral or background liver iron deposition were analyzed.ResultsA PTHR on T2*WI was observed in 23 of 39 (59%) HCCs. There was no significant difference in the histopathologic fibrous capsule findings (P = 0.394). In the semiquantitative methods, both peritumoral and background liver iron deposition grade were significantly higher in HCCs with a PTHR compared with HCCs without a PTHR (P < 0.001). The mean optical density in HCCs with a PTHR was significantly higher compared with HCCs without a PTHR, in the quantitative peritumoral (42244.1 ± 20854.9 vs 18739.1 ± 12258.7, respectively; P < 0.001) and background liver iron deposition analyses (35554.7 ± 19854.8 vs 17292.4 ± 11605.8, respectively; P < 0.001). Tumor size (P = 0.005), etiology (P = 0.001), and degree of fibrosis (P = 0.042) were significantly associated with the presence of a PTHR.ConclusionA PTHR in HCCs on T2*WIs was strongly associated with peritumoral iron deposition in the iron-deposited background liver but not with the fibrous capsule.

scholarly journals CT and MRI Findings in Cerebral Aspergilloma

2017 ◽  
Vol 190 (10) ◽  
pp. 967-970 ◽  
Author(s):  
Friederike Gärtner ◽  
Julia Forstenpointner ◽  
Birgit Ertl-Wagner ◽  
Babak Hooshmand ◽  
Christian Riedel ◽  
...  
Keyword(s):  
Imaging Features ◽  
Mri Imaging ◽  
Mri Findings ◽  
Diffusion Restriction ◽  
Medical Centers ◽  
Key Points ◽  
Internal Side ◽  
Abscess Wall ◽  
Improve Clinical Outcome ◽  
Ct And Mri

Purpose Invasive aspergillosis usually affects immunocompromised patients. It carries a high risk of morbidity and mortality and usually has a nonspecific clinical presentation. Early diagnosis is essential in order to start effective treatment and improve clinical outcome. Materials and Methods In a retrospective search of the PACS databases from two medical centers, we identified 9 patients with histologically proven cerebral aspergilloma. We systematically analyzed CT and MRI imaging findings to identify typical imaging appearances of cerebral aspergilloma. Results CT did not show a typical appearance of the aspergillomas. In 100 % (9/9) there was a rim-attenuated diffusion restriction on MRI imaging. Multiple hypointense layers in the aspergillus wall, especially on the internal side, were detected in 100 % on T2-weighted imaging (9/9). Aspergillomas were T1-hypointense in 66 % of cases (6/9) and partly T1-hyperintense in 33 % (3/9). In 78 % (7/9) of cases, a rim-attenuated diffusion restriction was detected after contrast agent application. Conclusion Nine cases were identified. Whereas CT features were less typical, we observed the following imaging features on MRI: A strong, rim-attenuated diffusion restriction (9/9); onion layer-like hypointense zones, in particular in the innermost part of the abscess wall on T2-weighted images (9/9). Enhancement of the lesion border was present in the majority of the cases (7/9). Key points  Citation Format

scholarly journals Clinical and imaging features of carcinosarcoma of the uterus and cervix

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Liming Li ◽  
Wenpeng Huang ◽  
Kangkang Xue ◽  
Leiyu Feng ◽  
Yijing Han ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
High Signal ◽  
Imaging Features ◽  
Mri Imaging ◽  
Diffusion Weighted Image ◽  
Resonance Imaging ◽  
Endometrial Thickening ◽  
Staging Accuracy ◽  
Magnetic Resonance Imaging Mri ◽  
Ct And Mri

Abstract Aim The purpose of our study was to analyze the clinical and imaging features of uterine carcinosarcoma (UCS) and cervical carcinosarcoma (CCS), and to explore the diagnostic and staging accuracy of computed tomography (CT) and magnetic resonance imaging (MRI) examinations. Methods 41 patients including 37 with UCS and 4 with CCS from July 2011 to September 2020 were enrolled in the study. Of the 37 UCS cases, 7 had CT images, 27 had MRI images, and 3 had both CT and MRI images. The Clinical data, CT or MRI imaging findings were analyzed. Diagnosis and staging accuracy of CT and MRI images were also analyzed. Results Carcinosarcoma usually occurs in postmenopausal women (40/41), with the typical clinical symptom being vaginal bleeding (33/41). The CA125 degree was significantly different between the two invasion depth groups (p = 0.011). Most uterine carcinosarcomas showed unclear boundaries, uneven density, low or equal signal on T1WI, high or mixed signal on T2WI, uneven high signal on diffusion-weighted image (DWI), and mild enhancement. The diagnostic accuracies of CT and MRI for carcinosarcoma were 0% and 3.33%, respectively. The diagnostic accuracy for malignant tumors on CT and MRI was 50% and 83.33%, respectively. Conclusions Carcinosarcoma lesions presented with huge mass filling in the cavity, and some presented with small polypoid lesions or endometrial thickening. Evaluation of lymph node metastasis is a significant challenge for imaging staging.

Imaging features of primary renal lymphoma

2017 ◽  
Vol 59 (1) ◽  
pp. 114-120 ◽  
Author(s):  
Qingqiang Zhu ◽  
Wenrong Zhu ◽  
Jingtao Wu ◽  
Wenxin Chen
Keyword(s):  
Multislice Computed Tomography ◽  
Low Grade ◽  
Imaging Features ◽  
Mri Imaging ◽  
Abdominal Vessels ◽  
Renal Lymphoma ◽  
Renal Enlargement ◽  
Magnetic Resonance Imaging Mri ◽  
Mri Characteristics ◽  
Ct And Mri

Background Cases of primary renal lymphoma (PRL) are quite rare and are often mistaken for renal cell carcinoma. Purpose To determine the multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) characteristics of PRL. Materials and Methods Twenty-three patients with PRL were identified by CT and MRI, and their tumor characteristics were assessed. Results Tumors exhibited single or multifocal nodules (n = 19) and diffuse renal enlargement (n = 4). Twenty-two tumors exhibited an infiltrative appearance. There was no evidence of calcification in any of the cases. Twenty-one tumors displaced or wrapped around abdominal vessels rather than encasing them. Enlarged retroperitoneal nodes were observed in three cases. Neither extension into the venous system nor distant metastasis was found. Tumor enhancement was of low attenuation compared with that of normal renal cortex and medulla ( P < 0.05). PRL was isointense on T1-weighted imaging, slightly hypointense on T2-weighted imaging and hyperintense on diffusion-weighted imaging. Twenty-two patients exhibited biopsy-confirmed PRN. There were four, 12, and seven cases of low-grade, intermediate-grade, and high-grade tumors, respectively. Patient were followed up over 16 to 166 months. Six patients died within three years and five patients died within five years. Conclusion Infiltrative appearance and tumor displacement or extension around abdominal vessels rather than vessel encasement are common findings on CT or MRI imaging and may suggest a diagnosis of PRL.

Chordoma: 18F-FDG PET/CT and MRI imaging features

2021 ◽  
Author(s):  
Joshua T. Olson ◽  
Doris E. Wenger ◽  
Peter S. Rose ◽  
Ivy A. Petersen ◽  
Stephen M. Broski
Keyword(s):  
Fdg Pet ◽  
Imaging Features ◽  
Mri Imaging ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Ct And Mri

scholarly journals The peritumoral hypointense rim around hepatocellular carcinoma on T2*-weighted magnetic resonance imaging: radiologic-pathologic correlation

2021 ◽  
Author(s):  
Yoshinori Tsukahara ◽  
Yukinori Okajima ◽  
Akira Yamada ◽  
Masanobu Momose ◽  
Takeshi Uehara ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Optical Density ◽  
Quantitative Methods ◽  
Iron Deposition ◽  
Fibrous Capsule ◽  
Blue Staining ◽  
Liver Iron ◽  
Significant Difference ◽  
Weighted Magnetic Resonance Imaging ◽  
Histopathologic Findings

Abstract Background: A peritumoral hypointense rim (PTHR) is sometimes observed around hepatocellular carcinoma (HCC) on T2*-weighted images (T2*WIs). We aimed to investigate the association between the PTHR and histopathologic findings on T2*WIs.Methods: We assessed the presence of a PTHR on T2*WIs in 39 pathologically proven HCCs from April 2012 to December 2013. Prussian blue staining was performed, and iron deposition was evaluated by semiquantitative and quantitative methods. Optical density was used in the quantitative methods. The associations between a PTHR on T2*WI and histopathologic peritumoral or background liver iron deposition were analyzed.Results: A PTHR on T2*WI was observed in 23 of 39 (59%) HCCs. There was no significant difference in the histopathologic fibrous capsule findings (P = 0.394). In the semiquantitative methods, both peritumoral and background liver iron deposition grade were significantly higher in HCCs with a PTHR compared with HCCs without a PTHR (P < 0.001). The mean optical density in HCCs with a PTHR was significantly higher compared with HCCs without a PTHR, in the quantitative peritumoral (42244.1 ± 20854.9 vs 18739.1 ± 12258.7, respectively; P < 0.001) and background liver iron deposition analyses (35554.7 ± 19854.8 vs 17292.4 ± 11605.8, respectively; P < 0.001). Tumor size (P = 0.005), etiology (P = 0.001), and degree of fibrosis (P = 0.042) were significantly associated with the presence of a PTHR.Conclusions: A PTHR in HCCs on T2*WIs was strongly associated with peritumoral iron deposition in the iron-deposited background liver but not with the fibrous capsule.

CT and MRI imaging features and long-term follow-up of adult Wilms’ tumor

2015 ◽  
Vol 57 (7) ◽  
pp. 894-900 ◽  
Author(s):  
Jingtao Wu ◽  
Qingqiang Zhu ◽  
Wenrong Zhu ◽  
Wenxin Chen
Keyword(s):  
Wilms Tumor ◽  
Imaging Features ◽  
Mri Imaging ◽  
Long Term Follow Up ◽  
Ct And Mri

scholarly journals Diagnostic value of lung ultrasound in patients with interstitial lung disease: a retrospective study

2019 ◽  
Author(s):  
Jun-Hong Yan ◽  
Lei Pan ◽  
Yan-Bing Gao ◽  
Guang-he Cui ◽  
Yue-Heng Wang
Keyword(s):  
Retrospective Study ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Clinical Diagnosis ◽  
Lung Ultrasound ◽  
False Negative ◽  
Laboratory Data ◽  
Negative Results ◽  
False Negative Results ◽  
Significant Difference

Abstract Background Interstitial lung disease (ILD) is a serious threat to human health due to its difficult diagnosis and lack of effective treatment. Lung ultrasound (LUS) has recently been applied to the detection of ILD, and butthe data on its role in the diagnosis of ILD remain limited. The aim of this study was to explore the value of LUS in the diagnosis of ILD.Methods This retrospective study was carried out by reviewing the medical records of patients admitted to a respiratory ward from June 2018 to July 2019. Only patients discharged with a clinical diagnosis of ILD and underwent high-resolution computerised tomography (HRCT) and LUS within a week were selected. Basic information about the patients, laboratory data, characteristic mages of LUS scans and diagnosis results of HRCT and LUS were collected. The sensitivity of LUS and HRCT in the diagnosis of ILD was calculated, and clinical diagnosis was applied as the gold standard.Results A total of 32 patients with a clinical diagnosis of ILD were enrolled. Out of the 32 patients, 5 patients (15.63%) had false negative results in LUS, and 3 (9.38%) had false negative results in HRCT. False positive cases were not observed. All patients were diagnosed with ILD, and thus, the specificity of the examination could not be counted. With the clinical diagnosis of ILD as the gold standard, the sensitivity values of LUS and HRCT for the diagnosis of ILD were 0.84 (0.67–0.95) and 0.91 (0.75–0.98), respectively. No significant difference in sensitivity was observed between the two groups ( P =0.4795).Conclusions LUS is not inferior to HRCT in the diagnosis of ILD. Considering its safety, low cost, portability and practicability, LUS should be considered as the first-line imaging tool for patients with suspected ILD.

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