Connect your needle to a smartphone to increase EUS FNA sample quality and diagnostic accuracy of solid pancreatic masses: a randomized trial

Endoscopy ◽  
2021 ◽  
Author(s):  
Mihai Ciocirlan ◽  
Anca Gheorghiu ◽  
Dana Bilous ◽  
Miruna Cruceru ◽  
Georgiana Mănăilă ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Randomized Trial ◽  
Random Order ◽  
Sample Quality ◽  
Pancreatic Masses ◽  
Adequate Quality ◽  
High Cellularity ◽  
Specimen Quality ◽  
Solid Lesions

Background and study aims. EUS FNA is recommended for diagnosis of solid pancreatic masses. We aimed to evaluate if a high needle movement acceleration value during puncture increases diagnostic accuracy. Patients and methods. EUS FNA needle acceleration was measured using a PocketLab accelerometer connected by Bluetooth to a smartphone. Two passes (fast and slow) with higher and respectively lower than 1g needle acceleration values were performed in random order. Sample cellularity and quality were measured by semiquantitative scales. Results. 51 patients were included (32 women, mean age 63). Mean acceleration values were 1.59 ± 0.66g for fast pass and 0.32 ± 0.19g for slow pass, p < 10-3. Fast pass yielded significantly higher EUS FNA accuracy (84.3% vs. 68.6%, p = 0.021) and adequate quality scores (94.1% vs. 76.5%, p = 0.007). High cellularity score frequencies were similar (15.7% vs. 11.8%, p = 0.317). Conclusions. A higher than 1g EUS FNA needle acceleration may increase diagnostic accuracy and specimen quality of pancreatic solid lesions.

Wet- versus dry-suction techniques for endoscopic ultrasound-guided fine-needle aspiration of solid lesions: a multicenter randomized controlled trial

Endoscopy ◽  
2020 ◽  
Vol 52 (11) ◽  
pp. 995-1003 ◽  
Author(s):  
Yun Wang ◽  
Rong-hua Wang ◽  
Zhen Ding ◽  
Shi-yun Tan ◽  
Qian Chen ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Diagnostic Accuracy ◽  
Controlled Trial ◽  
Needle Aspiration ◽  
Sampling Techniques ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Randomized Controlled ◽  
Specimen Quality ◽  
Solid Lesions

Abstract Background The optimal sampling techniques for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) remain unclear and have not been standardized. The aim of this study was to compare the wet-suction and dry-suction techniques for sampling solid lesions in the pancreas, mediastinum, and abdomen. Methods This was a multicenter, crossover, randomized controlled trial with randomized order of sampling techniques. The 296 consecutive patients underwent EUS-FNA with 22G needles and were randomized in a ratio of 1:1 into two separate groups that received the dry-suction and wet-suction techniques in a different order. The primary outcome was to compare the histological diagnostic accuracy of dry suction and wet suction for malignancy. The secondary outcomes were to compare the cytological diagnostic accuracy and specimen quality. Results Among the 269 patients with pancreatic (n = 161) and non-pancreatic (n = 108) lesions analyzed, the wet-suction technique had a significantly better histological diagnostic accuracy (84.9 % [95 % confidence interval (CI) 79.9 % – 89.0 %] vs. 73.2 % [95 %CI 67.1 % – 78.7 %]; P = 0.001), higher specimen adequacy (94.8 % vs. 78.8 %; P < 0.001), and less blood contamination (P < 0.001) than the dry-suction technique. In addition, sampling non-pancreatic lesions with two passes of wet suction provided a histological diagnostic accuracy of 91.6 %. Conclusions The wet-suction technique in EUS-FNA generates better histological diagnostic accuracy and specimen quality than the dry-suction technique. Furthermore, sampling non-pancreatic lesions with two passes of EUS-FNA with wet suction may provide a definitive histological diagnosis when rapid on-site evaluation is not routinely available.

The effect of transmission bandwidth on diagnostic accuracy in remote fetal ultrasound scanning

1997 ◽  
Vol 3 (4) ◽  
pp. 209-214 ◽  
Author(s):  
R. Wootton ◽  
J. Dornan ◽  
N. M. Fisk ◽  
A. Harper ◽  
C. Barry-Kinsella ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Random Order ◽  
Video Tape ◽  
Technical Quality ◽  
Fetal Ultrasound ◽  
Transmission Bandwidth ◽  
Significant Difference ◽  
The Uk ◽  
Viewing Sessions

Six subspecialists with considerable experience in fetal ultrasound viewed a selection of pre-recorded ultrasound scans. Scans from 18 patients recorded on VHS video-tape were supplied from five centres in the UK and Ireland, each made on a high-resolution ultrasound machine by an experienced sonologist at a referral centre. Each observer viewed the scans on a large display monitor in an individual viewing booth. The scans were viewed in random order, at randomly selected bandwidths. Observers, who were blinded to both recording and bandwidth, assessed the technical quality on a five-point Likert scale. They also recorded their diagnosis. The six observers each carried out 32 viewing sessions, which gave a total of 192 viewings. There was no significant difference in the perceived technical quality of the scans between the two bandwidths used P 0.09 . Of the 84 recordings transmitted at 1920 kbit s, 71 85 were diagnosed correctly or half correctly' and 13 15 were misdiagnosed. Of the 95 recordings transmitted at 384 kbit s, 66 69 were diagnosed correctly or half correctly' and 29 31 were misdiagnosed. This difference was significant P 0.03. The results indicate that although there were no perceived differences in technical quality between recordings transmitted at 384 or 1920 kbit s, diagnostic accuracy was marginally worse at the lower bandwidth. This suggests that the higher bandwidth conveys more detail and information to the observer, which in turn enables more accurate diagnosis. However, further work is required before a definitive choice can be made about the optimum transmission bandwidth for remote fetal ultrasound studies.

Cancer pain management

2014 ◽  
Vol 155 (3) ◽  
pp. 93-99
Author(s):  
Péter Heigl
Keyword(s):  
Quality Of Life ◽  
Pain Management ◽  
Pain Relief ◽  
Life Expectancy ◽  
Cancer Pain ◽  
Cancer Pain Management ◽  
Medical Activity ◽  
Short Summary ◽  
Adequate Quality

Pain is a significant and alarming symptom of cancer seriously affecting the activity and quality of life of patients. Recent research proved that inadequate analgesia shortens life expectancy. Therefore, pain relief is not only a possibility but a professional, ethical and moral commitment to relieve patients from suffering, as well as ensure their adequate quality of life and human dignity. Proper pain relief can be achieved with medical therapy in most of the cases and the pharmacological alternatives are available in Hungary. Yet medical activity regarding pain relief is far from the desired. This paper gives a short summary of the guidelines on medical pain management focusing particularly on the use of opioids. Orv. Hetil., 2014, 155(3), 93–99.

Deficiencies in Silicone Impression for Crowns and Bridges

2017 ◽  
Vol 68 (10) ◽  
pp. 2317-2319
Author(s):  
Claudia Florina Andreescu ◽  
Oana Botoaca ◽  
Horia Mihail Barbu ◽  
Doina Lucia Ghergic ◽  
Anamaria Bechir ◽  
...  
Keyword(s):  
Dental Practice ◽  
Present Study Deal ◽  
Dental Crowns ◽  
Impression Materials ◽  
Dental Practitioners ◽  
Adequate Quality ◽  
Dental Impression ◽  
Single Crowns

There are many steps in fabrication of dental crowns and bridges at which an error can occur, and a technician can only fabricate a quality restoration if the impression itself is of adequate quality. All dental practitioners should have the ability to evaluate the quality of dental impression before sending to the laboratory. Elastomeric silicones (polysiloxane) are the most utilised impression materials in dental practice. The present study deal with the deficiencies of silicones dental impressions sent to commercial dental laboratories for fabrication of single crowns and bridges.

scholarly journals “Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study”

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Brett C. Bade ◽  
Geliang Gan ◽  
Fangyong Li ◽  
Lingeng Lu ◽  
Lynn Tanoue ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Lung Cancer ◽  
Randomized Trial ◽  
Cancer Biomarkers ◽  
Advanced Stage ◽  
Home Based ◽  
Advanced Stage Lung Cancer ◽  
Stage Lung Cancer

Abstract Background Lung cancer survivors need more options to improve quality of life (QoL). It is unclear to what extent patients with advanced stage disease are willing to participate in home-based physical activity (PA) and if these interventions improve QoL. The goal of our study was to determine interest in participating in our 3-month home-based walking regimen in patients with advanced stage lung cancer. We used a randomized design to evaluate for potential benefit in PA and patient-reported outcomes. Methods We performed an open-label, 1:1 randomized trial in 40 patients with stage III/IV non-small cell lung cancer (NSCLC) evaluating enrollment rate, PA, QoL, dyspnea, depression, and biomarkers. Compared to usual care (UC), the intervention group (IG) received an accelerometer, in-person teaching session, and gain-framed text messages for 12 weeks. Results We enrolled 56% (40/71) of eligible patients. Participants were on average 65 years and enrolled 1.9 years from diagnosis. Most patients were women (75%), and receiving treatment (85%) for stage IV (73%) adenocarcinoma (83%). A minority of patients were employed part-time or full time (38%). Both groups reported low baseline PA (IG mean 37 (Standard deviation (SD) 46) vs UC 59 (SD 56) minutes/week; p = 0.25). The IG increased PA more than UC (mean change IG + 123 (SD 212) vs UC + 35 (SD 103) minutes/week; p = 0.051)). Step count in the IG was not statistically different between baseline (4707 step/day), week 6 (5605; p = 0.16), and week 12 (4606 steps/day; p = 0.87). The intervention improved EORTC role functioning domain (17 points; p = 0.022) with borderline improvement in dyspnea (− 13 points; p = 0.051) compared to UC. In patients with two blood samples (25%), we observed a significant increase in soluble PD-1 (219.8 (SD 54.5) pg/mL; p < 0.001). Conclusions Our pilot trial using a 3-month, home-based, mobile health intervention enrolled over half of eligible patients with stage III and IV NSCLC. The intervention increased PA, and may improve several aspects of QoL. We also identified potential biomarker changes relevant to lung cancer biology. Future research should use a larger sample to examine the effect of exercise on cancer biomarkers, which may mediate the association between PA and QoL. Clinical trial registration Clinicaltrials.gov (NCT03352245).

scholarly journals Textile Recognition and Sorting for Recycling at an Automated Line Using Near Infrared Spectroscopy

Recycling ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 11
Author(s):  
Kirsti Cura ◽  
Niko Rintala ◽  
Taina Kamppuri ◽  
Eetta Saarimäki ◽  
Pirjo Heikkilä
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Automated Recognition ◽  
Textile Materials ◽  
Input Material ◽  
Adequate Quality ◽  
Automated Line

In order to add value to recycled textile material and to guarantee that the input material for recycling processes is of adequate quality, it is essential to be able to accurately recognise and sort items according to their material content. Therefore, there is a need for an economically viable and effective way to recognise and sort textile materials. Automated recognition and sorting lines provide a method for ensuring better quality of the fractions being recycled and thus enhance the availability of such fractions for recycling. The aim of this study was to deepen the understanding of NIR spectroscopy technology in the recognition of textile materials by studying the effects of structural fabric properties on the recognition. The identified properties of fabrics that led non-matching recognition were coating and finishing that lead different recognition of the material depending on the side facing the NIR analyser. In addition, very thin fabrics allowed NIRS to penetrate through the fabric and resulted in the non-matching recognition. Additionally, ageing was found to cause such chemical changes, especially in the spectra of cotton, that hampered the recognition.

Sign in / Sign up

Export Citation Format

Share Document