9 Spine Infections

Spine infections can have significant morbidity and mortality if not identified and treated appropriately. This category of orthopaedic infections can include infections involving the epidural space (spinal epidural abscesses), vertebral column (vertebral osteomyelitis), or the intervertebral disks (diskitis). These conditions can predispose patients to significant consequences including neurologic compromise, deformity, and pain. Accurate diagnosis of spine infections is based on clinical history and examination, along with appropriate imaging and laboratory tests. Treatment of these infections entails medical management with antibiotic therapy, or, in cases with progressive neurologic deficit or deformity, surgical methods that include open decompression with correction of deformity as indicated.

2020 ◽  
Vol 7 (2) ◽  
pp. 64-67
Author(s):  
Abu Sayeed Mohammad ◽  
Shahadat Hossain ◽  
Zulfiqur Hossain Khan

Background: Crack sole may produce significant morbidity among the physical labourer. Objective: The purpose of this study was to find out the patch test result in crack sole which was due to allergic contactants. Methodology: This test was conducted in the Department at Dermatology and Venereology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2001 to June 2002 for a period of one year. Patients with crack sole were selected as study population. All patients were asked about the details clinical history. Patch test was done by individually prepared alminium Finn Chamber mounted on scanpore tape. Result: A total number of 15 patients were recruited for this study after fulfilling the inclusion and exclusion criteria. The age range was 8 years to 70 years. Among 15 patients 3 patients were patch test positive remaining 12 patients were patch test negative. Two patient were female and one was male. Conclusion: In conclusion patch test is positive among the crack sole patients. Journal of Current and Advance Medical Research 2020;7(2): 64-67


2015 ◽  
Vol 7 ◽  
pp. e2015039 ◽  
Author(s):  
Clare Miller ◽  
Barbara Bain

The laboratory haematologist has a role in the diagnosis of parasitic infections. Peripheral blood examination is critical in the diagnosis of malaria, babesiosis, filariasis and trypanosomiasis. Bone marrow examination is important in the diagnosis of leishmaniasis and occasionally leads to the diagnosis of other parasitic infections. The detection of eosinophilia or iron deficiency anaemia can alert the laboratory haematologist or physician to the possibility of parasitic infection. In addition to morphological skills, an adequate clinical history is important for speedy and accurate diagnosis, particularly in non-endemic areas.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Yuying Jiang ◽  
Amira F Gohara ◽  
Robert E. Mrak ◽  
Kenneth L. Muldrew

Aspergillosis is a commonly diagnosed fungal infection. Histopathologic examination alone can have diagnostic pitfalls due to the overlapping of fungal morphology. We report a case of Scedosporium boydii infection initially misdiagnosed as aspergillosis. The patient presented to the hospital with shortness of breath and chest and abdominal pain. Laboratory tests revealed leukocytosis and elevated serum liver enzymes, myoglobin and lipase. He died of hypotensive shock and brain abscesses despite antibiotic treatment. Autopsy revealed invasive fungal infection in the heart, thyroid, and brain with presence of 45-degree angled, branching hyphae. The initial diagnosis of aspergillosis was made; however, further molecular studies identified the organism as S. boydii. This report reveals the potential pitfalls of morphologic diagnosis alone; and the necessity of other testing modalities to render an accurate diagnosis which is crucial for appropriate.


2009 ◽  
Vol 28 (9) ◽  
pp. 848-850 ◽  
Author(s):  
Diana Tasher ◽  
Erez Armarnik ◽  
Avram Mizrahi ◽  
Ben Sira Liat ◽  
Shlomi Constantini ◽  
...  

2021 ◽  
Vol 12 ◽  
pp. 256
Author(s):  
Andreas Theofanopoulos ◽  
Petros Zampakis ◽  
Eleftheria Antoniadou ◽  
Dimitrios Papadakos ◽  
Dionysia Fermeli ◽  
...  

Background: Spontaneous spinal epidural hematomas (SSEHs) are often attributed to anticoagulation. Although they are rare, they may contribute to significant morbidity and mortality. Case Description: An 83-year-old female with a history of atrial fibrillation on apixaban, presented with 4 days of back pain, progressive lower extremity weakness and urinary retention. When the patient’s MRI showed a dorsal thoracolumbar SSEH, the patient underwent a T10–L3 laminectomy for hematoma evacuation. Within 2 postoperative months, her neurological deficits fully resolved. Conclusion: Apixaban is associated with SSEH resulting in severe neurological morbidity and even mortality. Prompt MRI imaging followed by emergency surgical decompressive surgery may result in full resolution of neurological deficits.


2020 ◽  
Vol 8 (1) ◽  
pp. e001015
Author(s):  
Nicole Marie Szafranski ◽  
Aude Castel ◽  
Adrien-Maxence Hespel ◽  
Vincent Dore

A one-month-old male goat kid presented with a three weeks’ history of progressive neurological deficits and progressive tetraparesis. Initial therapeutic strategy with antimicrobial, anti-inflammatory and selenium supplementation only partly relieved clinical signs. Digital radiographs were performed antemortem and revealed a pathological fracture of the vertebral column. A CT scan was performed immediately postmortem. The imaging revealed lysis of the vertebral bodies of T8, T9, T12 and T13 and focal narrowing of the vertebral canal consistent with infectious osteomyelitis of the thoracic vertebral column. Histopathological examination and microbiological testing confirmed a multifocal discospondylitis and vertebral osteomyelitis of mixed bacterial origin.


2017 ◽  
Vol 9 (1) ◽  
pp. 28-31
Author(s):  
Lília Ferraria ◽  
Sílvia Alves ◽  
Helena Rosa ◽  
Mário Santos ◽  
Luis Antunes

ABSTRACT Aim To report a case of unilateral choanal atresia diagnosed in a 48-year-old, presenting with fatigue as the major symptom. To highlight the importance of a detailed clinical history and physical examination for an accurate diagnosis. Background Choanal atresia is an uncommon and often poorly recognized cause of unilateral or bilateral nasal obstruction. It is a congenital condition that occurs in approximately 1 in 5,000 to 8,000 live births. Case report This study reports a case of unilateral choanal atresia diagnosed in a 48-year-old presenting with fatigue as the major symptom. The patient presented with a lifelong history of tiredness investigated in cardiology. She was treated by a combined transseptal and transnasal endoscopic surgical technique. Topic use of mitomycin was performed with no use of stents, with clinical regression of the symptoms. Conclusion Unilateral choanal atresia usually presents in younger patients but can be undiagnosed until adulthood due to the nonspecific nature of the symptoms. This diagnosis should be, therefore, considered in all ages and bedside diagnostic procedures should, then, be done. Nasal endoscopy and computed tomography (CT) scan are the gold standard for the diagnosis. The use of stents and mitomycin C topically as an adjunct to the surgical repair of choanal atresia is a controversial subject. How to cite this article Ferraria L, Alves S, Rosa H, Santos M, Antunes L. Unilateral Congenital Choanal Atresia in a 48-Year-Old Patient. Int J Otorhinolaryngol Clin 2017;9(1):28-31.


1976 ◽  
Vol 195 (1118) ◽  
pp. 115-127 ◽  

The demand for effective ‘hindsight’ or post-conceptual methods of family planning appears to be increasing throughout the world. Medical methods are appealing, because potentially they may be self-administered. At present, prostaglandins or their 15-methyl analogues are being studied on patients who are up to one month late with their menses. Of all the routes used the vaginal route appears the best. Side effects include nausea, vomiting, diarrhoea and abdominal cramps and these often need medication to counteract them. The methods are well short of 100% efficiency. Accurate diagnosis of pregnancy and gestation is often a problem and this renders the method unsuitable for an ‘over the counter’ self-administration pill. Since the introduction of the ‘menstrual extraction’ syringe and the Karman curette, termination of pregnancy at up to 8 weeks of amenorrhoea has become substantially easier and safer, especially when combined with local anaesthetics. Dilation is rarely required and the whole procedure rarely takes more than 5–10 min. Post-operative complications appear few and acceptable.


2017 ◽  
Vol 56 (2) ◽  
Author(s):  
Cristina Costales ◽  
Susan M. Butler-Wu

ABSTRACT Rapid diagnosis and treatment of an infected joint are paramount in preserving orthopedic function. Here, we present a brief review of the many challenges associated with the diagnosis of both septic arthritis and prosthetic joint infections. We also discuss the many laboratory tests currently available to aid in the accurate diagnosis of joint infection, as well as emerging diagnostics that may have future utility in the diagnosis of these challenging clinical entities.


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