Quality of Life in Pediatric Patients with Allergic Rhinitis treated at the Medical Clinic of Integrated Education – Unisul

Introduction Allergic rhinitis is a common disease among children and adolescents, reaching up to 40% of the population. During childhood, it is usually underdiagnosed because it has nonspecific symptoms. It has a negative impact on quality of life and may predispose to comorbidities. The diagnosis is clinical and treatment aims prevention. Objective The objective of this study is to evaluate the quality of life in pediatric patients with allergic rhinitis. Methods This is an observational study with cross-sectional design. The population consisted of pediatric patients with allergic rhinitis treated at the Medical Clinic of Integrated Education (MCIE) – Universidade do Sul de Santa Catarina - Unisul, Tubarão, SC, Brazil. We collected data from March to June 2016 through the application of the Sociodemographic and Health Questionnaire, rhinitis module of the International Study of Asthma and Allergies in Childhood Questionnaire and the Rhinoconjunctivitis Quality of Life Questionnaire Modified. Results Out of the 69 respondents, 52.2% were boys with a mean age of 10.13 years old. The predominant education level of parents/guardians was incomplete second grade and average income level was two minimum wages. 81.2% said they had previous treatment for AR, 30.4% had asthma and 7.2% eczema. Incidence of patients smoking was absent and family (parents/guardians) smoking was 17.4%. March to July were the months of highest symptom occurrence, slightly disturbing daily activities. The mean value of severity was 51.9, nasal symptoms were the most uncomfortable, and nasal itchiness was the most cited. Conclusion Our results highlight that allergic symptoms negatively impact the life of people with allergic rhinitis, with a predominance of nasal symptoms, especially nasal itchy, representing a poor quality of life of the interviewed.

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The impact of allergic rhinitis on symptoms, and quality of life using the new criterion of ARIA severity classification

Rhinology Journal ◽

10.4193/rhino11.071 ◽

2012 ◽

Vol 50 (1) ◽

pp. 33-36

Author(s):

Antonio Valero ◽

Rosa Munoz-Cano ◽

Joaquin Sastre ◽

Ana M. Navarro ◽

Enrique Marti-Guadano ◽

...

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Common Disease ◽

Life Questionnaire ◽

Nasal Symptoms ◽

Severity Classification ◽

New Criterion ◽

The Impact ◽

Severity Criterion

Introduction: Allergic rhinitis (AR) is a common disease with major socieconomic burden and a significant impact on quality of life. Objective: The objective of the study was to assess the impact of AR severity, using the modified ARIA (m-ARIA) severity criterion in order to discriminate among moderate and severe AR, in symptoms and quality of life assessed with the questionnaire ESPRINT-15. Methods: The specific quality of life questionnaire (ESPRINT-15) was applied in over thousand untreated RA patients. Severity was evaluated by the m-ARIA classification, which categorizes AR as mild, moderate, and severe. Nasal symptoms were evaluated by using categorized (none, low, middle, and high) Total Four Symptom Score (T4SS). Results: Using the m-ARIA severity classification, significant differences in quality of life, both global score and specific domains, and categorized T4SS were found among the AR severity groups. Conclusion: Modified ARIA severity classification in mild, moderate, and severe allergic rhinitis clearly discriminates the impact of AR in all domains of quality of life and categorized symptom`s score.

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The impact of allergic rhinitis on symptoms, and quality of life using the new criterion of ARIA severity classification

Rhinology Journal ◽

10.4193/rhino.11.071 ◽

2012 ◽

Vol 50 (1) ◽

pp. 33-36

Author(s):

Antonio Valero ◽

Rosa Munoz-Cano ◽

Joaquin Sastre ◽

Ana M. Navarro ◽

Enrique Marti-Guadano ◽

...

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Common Disease ◽

Life Questionnaire ◽

Nasal Symptoms ◽

Severity Classification ◽

New Criterion ◽

The Impact ◽

Severity Criterion

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Hyeonggaeyeongyo-Tang for Treatment of Allergic and Nonallergic Rhinitis: A Prospective, Nonrandomized, Pre-Post Study

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2016/9202675 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Min-Hee Kim ◽

Jaewoong Son ◽

Hae Jeong Nam ◽

Seong-Gyu Ko ◽

Inhwa Choi

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Life Questionnaire ◽

Nonallergic Rhinitis ◽

Prick Test ◽

Chronic Rhinitis ◽

Nasal Symptoms ◽

Significant Difference

Hyeonggaeyeongyo-tang (HYT) is an ancient formula of oriental medicine traditionally used to treat rhinitis; however, clinical evidence has not yet been established. The aim of this study was to investigate the short-term and long-term efficacy and safety of HYT for chronic rhinitis. Adult subjects with chronic rhinitis symptoms were recruited. The subjects received HYT for 4 weeks and had follow-up period of 8 weeks. Any medicines used to treat nasal symptoms were not permitted during the study. The skin prick test was performed to distinguish the subjects with allergic rhinitis from those with nonallergic rhinitis. After treatment, the total nasal symptoms score and the Rhinoconjunctivitis Quality of Life Questionnaire score significantly improved in the whole subject group, in the allergic rhinitis group, and in the nonallergic rhinitis group, with no adverse events. This improvement lasted during a follow-up period of 8 weeks. Total IgE and eosinophil levels showed no significant difference after treatment in the allergic rhinitis group. HYT improved nasal symptoms and quality of life in patients with allergic rhinitis and nonallergic rhinitis. This is the first clinical study to evaluate the use of HYT to treat patients with rhinitis. This trial has been registered with the ClinicalTrials.gov IdentifierNCT02477293.

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Comparison of Quality of Life and Nasal Symptoms in Chronic Rhinitis Patients Between Before and After Treatment

Ramathibodi Medical Journal ◽

10.33165/rmj.2019.42.2.149814 ◽

2019 ◽

Vol 42 (2) ◽

pp. 21-29

Author(s):

Malinee Tongdee ◽

Nichapha Dechapaphapitak ◽

Thanuchporn Kafaksom ◽

Umaporn Udomsubpayakul ◽

Chamard Wongsa ◽

...

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Short Form ◽

Rank Test ◽

Common Disease ◽

Chronic Rhinitis ◽

Nasal Symptoms ◽

Before And After ◽

The Difference

Background: Chronic rhinitis is a common disease which impacts the quality of life. The symptom of diseases could be controlled after treatment. However, the difference in the quality of life and symptoms after 3 months of treatment is not documented. Objective: To compare the quality of life in chronic rhinitis patients before and at 3 months after treatment. Methods: Prospective study in new cases of chronic rhinitis patients at adult allergy clinic, Ramathibodi Hospital, from August 2017 to March 2018. Assessment of quality of life and nasal symptoms was performed by using the short form 36 health survey questionnaire (SF36) and the rhinoconjunctivitis quality of life questionnaires (RCQ36). Descriptive statistic, t test, and Wilcoxon signed rank test were applied in the data analysis. Results: Of 127 patients, 65.4% were female. Chronic rhinitis was classified as allergic rhinitis, non-allergic rhinitis, and unspecified rhinitis in 72.4%, 18.9%, and 8.7%, respectively. The result of the study showed that there was statistically significant improvement in the quality of life (SF36 and RCQ36 ) and the decrease of nasal and other symptoms score after 3 months of period treatment in chronic rhinitis patients (P < .05). Conclusions: The improvement in the quality of life (SF36 and RCQ36) and the decrease in nasal and other symptoms were documented after 3 months of treatment in chronic rhinitis patients.

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Self-Reported Allergic Rhinitis Prevalence and Related Factors in Civil Aviation Aircrew of China

Aerospace Medicine and Human Performance ◽

10.3357/amhp.5727.2021 ◽

2021 ◽

Vol 92 (1) ◽

pp. 25-31

Author(s):

Yin Bai ◽

Mosheng Hu ◽

Fengjie Ma ◽

Ke Liu ◽

Haijun Xu ◽

...

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Allergic Rhinitis ◽

Large Scale ◽

Civil Aviation ◽

Life Questionnaire ◽

Related Factors ◽

Flight Duration ◽

Nasal Symptoms

INTRODUCTION: Allergic rhinitis (AR) is a global health problem with gradually increasing prevalence. No large-scale, systematic, and comprehensive study on AR among civil aviation aircrew of China has been reported. We aimed to demonstrate the prevalence of and risk factors for self-reported AR among Chinese civil aviation aircrew.METHODS: This study randomly surveyed 4059 civil aviation aircrew members from 12 cities in mainland China. A structured questionnaire was tailored, designed, and electronically delivered to all participants. Based on self-reported results, prevalence of and risk factors for AR were calculated/analyzed.RESULTS: The prevalence of self-reported AR was 23.38%. Among aircrew members, 10.37% presented with ear barotraumas, whereas 9.95% reported symptom aggravation during flight. Of aircrew members, 10.32% had symptoms related to flight duration, whereas 4.43% of symptoms related to flight altitude. Significant differences between rhinorrhea and sneezing, as well as between nasal itching and sneezing, were observed in the Total Nasal Symptoms Scores (TNSS). The Rhino-conjunctivitis Quality of Life Questionnaire (RQLQ) showed significant correlation between each section. TNSS was significantly related to RQLQ. Both TNSS and RQLQ significantly correlated with flight time.CONCLUSIONS: The prevalence of self-reported AR among civil aviation aircrew is higher than the general population in China. The severity of nasal symptoms and complications are significantly associated with quality of life and flying duties.Bai Y, Hu M, Ma F, Liu K, Xu H, Wu X, Wang H. Self-reported allergic rhinitis prevalence and related factors in civil aviation aircrew of China. Aerosp Med Hum Perform. 2021; 92(1):2531.

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Fibromyalgia in the Patients With Allergic Rhinitis: Its Prevalence and Impact on the Quality of Life

American Journal of Rhinology and Allergy ◽

10.1177/1945892419864526 ◽

2019 ◽

Vol 33 (6) ◽

pp. 716-722 ◽

Cited By ~ 3

Author(s):

Selcan Gultuna ◽

Nihal Tezel ◽

Funda Seher Ozalp Ates

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Negative Impact ◽

Nottingham Health Profile ◽

Allergic Diseases ◽

Life Questionnaire ◽

American College Of Rheumatology ◽

Individual Domain ◽

Impaired Quality

Background Allergic rhinitis (AR) is a common allergic diseases which affect a patient’s quality of life. Another important disease which has a negative impact on quality of life is fibromyalgia (FM). Some studies have suggested that a probable relationship exists between atopic diseases and FM. Objectives This study was designed to determine the prevalence of FM and its impact on quality of life among AR patients. Methods One hundred five consecutive adult patients with AR who were between 18 and 57 years old were prospectively recruited in this study between April 2017 and May 2018. All patients were evaluated for the presences of FM. Patients were diagnosed with FM according to the classification criteria of the 2010 American College of Rheumatology. The patients’ quality of life was evaluated by Turkish versions of the Rhinoconjunctivitis Quality of Life Questionnaire and the Nottingham Health Profile (NHP). Results Thirty-four patients were diagnosed as having FM (32.4%). The percentage of FM was considerably higher than in the general population (2%–5%). Median individual domain scores except practical problems ( P = .108) and eyes symptoms ( P = .227) were significantly higher in AR with FM patients ( P < .001). All median levels of the NHP domains were significantly higher in AR with FM patients ( P < .001). Conclusion We would like to suggest that FM may be considered as one of the overlooked comorbid conditions in AR patients. Physicians should be aware of the occurrence of FM, especially in patients with impaired quality of life.

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Assessment of quality of life measured by rhinoconjuctivits quality of life questionnaire in patients of allergic rhinitis treated with commonly used oral antihistaminics

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20193186 ◽

2019 ◽

Vol 8 (8) ◽

pp. 1830

Author(s):

Ganesh S. Pentewar ◽

Ranjit J. Wagh

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Symptom Score ◽

Life Questionnaire ◽

Open Label ◽

Treatment Groups ◽

Quality Of Life Questionnaire ◽

Nasal Symptoms ◽

The Impact

Background: Nasal and non-nasal symptoms in allergic rhinitis (AR) can be assessed by measuring health related quality of life (HRQOL). Present study was to assess the impact of use of antihistaminic in AR which will affect the work productivity, sleep, frequent visits to health care professional and expenditure on medicines. For this evaluation, Rhinoconjuctivits Quality Of Life Questionnaire (RQLQ) has been used.Methods: In this study 52 patients with AR were randomized in an open-label, 4-arm, parallel group, single center study. Questionnaire information was obtained about allergy-related RQLQ. Subjects received either Tablet Cetirizine 5 mg, Levocetirizine 5 mg, Loratidine 5 mg or Fexofenadine 120 mg. Changes from baseline until the end of study visit (1 week following) were evaluated by RQLQ.Results: When compared between treatment groups using one-way ANOVA it was observed that there is no variation in RQLQ overall Score in all the four treatment groups and there is no difference from treatment to treatment. Overall RQLQ score was reduced maximum in Levocetirizine group. Individual symptoms of RQLQ that is sleep score, non-hay fever, practical problem, nasal symptom score, Eye symptom Score, activities Score, and emotion score were also improved in the Levocetirizine group.Conclusions: Patients of all four study groups showed an improved perception of their HRQL according to the RQLQ. Significant improvements are reported in nasal symptoms, daily activities, sleep and psychological impact. Our results provide support for an AR and its impact on quality of life. Our recommendation stipulating that levocetirizine is superior to rest drug group for the treatment of AR with safety and tolerability.

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Evaluation of efficacy and safety of montelukast and levocetirizine FDC tablet compared to montelukast and levocetirizine tablet in patients with seasonal allergic rhinitis: a randomized, double blind, multicentre, phase III trial

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20205625 ◽

2020 ◽

Vol 7 (1) ◽

pp. 83

Author(s):

Sagar Panchal ◽

Saiprasad Patil ◽

Hanmant Barkate

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Seasonal Allergic Rhinitis ◽

Phase Iii ◽

Fixed Dose ◽

Controlled Study ◽

Global Evaluation ◽

Double Blind ◽

Nasal Symptoms

Background: To evaluate efficacy, safety and tolerability of Montelukast 10 mg+levocetirizine 5 mg FDC compared to either montelukast 10 mg or levocetirizine 5 mg given alone in seasonal allergic rhinitis (SAR) patients.Methods: Phase III, multicentre, randomized, double blind, parallel group, active controlled study was conducted in 279 SAR patients at 16 sites across India. Efficacy was assessed using daytime nasal symptoms score (Primary efficacy outcome), night-time symptoms score, daytime eye symptom score, patient's global evaluation, physician's global evaluation, rhino-conjunctivitis quality-of-life score. Results: At end of treatment there was statistically significant evidence from the per protocol analysis that patients on FDC had a greater improvement in change from baseline in daytime nasal symptoms score than patients who received Montelukast (p=0.0266) or Levocetirizine (p=0.0409). These results were consistent with the Intent to treat analysis. Analysis of the secondary efficacy endpoints provided numerically greater improvement in the nighttime symptoms score, daytime eye symptoms score, and rhinoconjunctivitis quality-of-life scores in the FDC group as compared to the Montelukast group or Levocetirizine group. The FDC of Montelukast and Levocetirizine was found to be safe and generally well tolerated. The majority of adverse events were mild in severity, resolved without treatment and were unrelated to study medication.Conclusions: Fixed dose combination of Montelukast and Levocetirizine was safe, generally well tolerated and superior on efficacy compared to Montelukast or Levocetirizine in patients of seasonal allergic rhinitis.

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A betegség és a szociodemográfiai háttér hatása a cerebralis bénulásban szenvedő gyermekek életminőségére

Orvosi Hetilap ◽

10.1556/650.2021.31990 ◽

2021 ◽

Vol 162 (7) ◽

pp. 269-279

Author(s):

Melinda Fejes ◽

Beatrix Varga ◽

Katalin Hollódy

Keyword(s):

Quality Of Life ◽

Family Environment ◽

Negative Impact ◽

The Body ◽

Life Questionnaire ◽

Functional Difference ◽

Healthy Children ◽

Related Quality ◽

Health Related

Összefoglaló. Bevezetés: A kutatócsoport 99 fő, cerebralis paresisben (CP) szenvedő gyermek (8–18 éves) önállóan közölt életminőségét értékelte, és az eredményeket összehasonlította egy 237 fős kontrollcsoport adataival, amelyek hasonló életkorú, egészséges általános populációhoz tartozó gyermekektől származtak. Célkitűzés: A kutatás célja annak megismerése volt, hogy a CP-ben szenvedő gyermekek hogyan vélekednek egészségi állapotukról és társadalmi helyzetükről. Módszer: Életminőség-kérdőív alkalmazása. Betegségspecifikus és társadalmi-demográfiai mutatók mérése, kiértékelése. Eredmények: Az CP-ben szenvedő gyermekek és szüleik az egészséggel kapcsolatos életminőséget rosszabbnak ítélték meg, mint társaik. Eredményeink azt mutatják, hogy a női nem, a rosszabb motoros funkció és a komorbiditások (epilepszia, incontinentia és intellektuális károsodás) negatív hatású. A szülői vélemény alkalmas volt proxyjelentésként a korreláció mért erőssége miatt. Figyelemre méltó, hogy az agyi bénulás típusai közül az egyoldali spasticus CP-ben szenvedő gyermekek életminőség-értéke a legalacsonyabb. A válaszadók valószínűleg a test két oldala között lévő funkcionális különbséget érezték. A szellemi fogyatékosság a betegpopuláció több mint felénél fordult elő. Testvéreik között a mentális betegség 5,7-szer gyakoribb. A CP-s gyerekek családi környezete sokkal hátrányosabb volt, mint az egészséges gyermekeké. A kutatás eredményei alapján megállapítható, hogy a szülő alacsonyabb iskolai végzettsége és munkaerőpiaci inaktivitása, valamint az egyszülős család a CP-s gyerekeknél szignifikánsan magasabb arányban fordult elő, és ezek a tényezők negatív hatást gyakoroltak az életminőségre. Következtetés: A fogyatékkal élő gyermekek életminőségét a betegség és a szociodemográfiai környezet egyaránt befolyásolja. Orv Hetil. 2021; 162(7): 269–279. Summary. Introduction: Self-reported health-related quality of life (HRQoL) of 99 children (8–18 years) with cerebral palsy (CP) was assessed and compared with 237, age-matched healthy control children from the general population. Objective: The aim was to find out the opinions of children with CP about their health status and social condition. Method: Assessment of quality of life questionnaire was carried out. Measurements of disease-specific and sociodemographic variables were done. Results: Children with CP and their parents rated HRQoL poorer than their counterparts. Our results show that female sex, worse gross motor function and comorbidities (epilepsy, incontinence and intellectual impairment) had negative impact. The parental opinion was suitable as proxy report because of the measured strength of the correlation. Among the types of CP, interestingly, children with unilateral spastic CP had the poorest HRQoL. They were likely to feel a functional difference between the two sides of the body. Intellectual disability occurred in more than half of our patient population. Among their siblings, mental illness is 5.7 times more common. The family environment was much more disadvantageous than in the case of healthy children. As our study shows, lower education, inactive status in the labour market and single-parent family occurred at a much higher rate and worsened the quality of life. Conclusion: Quality of life of children with disability was influenced by both the sociodemographic background and the disease. Orv Hetil. 2021; 162(7): 269–279.

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Prevalence and impact of allergic rhinitis in school going children

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20211565 ◽

2021 ◽

Vol 7 (5) ◽

pp. 760

Author(s):

Sucheta Gupta ◽

Vinod Gupta ◽

Akhil Gupta

Keyword(s):

Quality Of Life ◽

Allergic Rhinitis ◽

Negative Impact ◽

Community Health Center ◽

Medical Intervention ◽

House Dust Mites ◽

Inflammatory Disorder ◽

Chronic Inflammatory Disorder ◽

Co Morbidity

Background: Allergic rhinitis (AR) is a chronic inflammatory disorder affecting the nasal mucosa. There is negative impact of AR on several aspects of day to day living and quality of life (QoL), which include: daily functioning, sleep, absenteeism, school productivity and academic performance. Almost 40% of children are being affected by AR.Method: An observational study was conducted on randomly selected 100 parents of school going children aging 2 to 15 years, attending OPD in community health center, Chenani, district Udhampur, J and K, for a period of one year from June 2018 to Nov 2018. Children having frequent episodes of allergic rhinitis were enquired about their history of sneezing, runner itchy nose and eyes, thick mucus, nasal blockage or breathless with associated symptoms were selected.Results: 81% of subjects had a worse problem during specific months of the year; and 67% had itchy-watery eyes. In 15% of subjects, AR impacted daily activities. A prevalence of 28% for nasal symptoms and 14% for allergic rhino-conjunctivitis was found. Study also showed significantly higher proportion of blockers (61%) than sneeze runners (39%). 56% children had one or more co morbidity, whereas 44% had ‘nil’ co-morbidities. The most common allergens were: pollens (grass, trees and weeds), house dust mites, pets, molds, fungi and food.Conclusions: AR adversely affects quality of life of patients and furthermore studies should be conducted for more clarity on the subject, besides a timely medical intervention and treatment could possibly avoid the rising morbidity associated with the disease.

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