Reliabilität einer elektronischen Version des EORTC QLQ C-30-Fragebogens zur Messung der gesundheitsbezogenen Lebensqualität bei Brustkrebspatientinnen

2017 ◽  
Vol 14 (02) ◽  
pp. A1-A53
Author(s):  
J Graf ◽  
AD Hartkopf ◽  
E Simoes ◽  
L Sebesteny ◽  
L Matthies ◽  
...  
Keyword(s):  
C 30 ◽  
Eortc Qlq

scholarly journals Quality of life among ovarian cancer survivors in Haji Adam Malik General Hospital Medan, Indonesia

2020 ◽  
Vol 11 (2) ◽  
pp. 133-139
Author(s):  
Kristivani Br Ginting ◽  
Muhammad Rizki Yaznil ◽  
M. Oky Prabudi ◽  
Lili Rahmawati
Keyword(s):  
Quality Of Life ◽  
Ovarian Cancer ◽  
Cancer Survivors ◽  
General Hospital ◽  
Detection Methods ◽  
Cross Sectional ◽  
Eortc Qlq C30 ◽  
C 30 ◽  
Eortc Qlq

Latar belakang: Kanker ovarium memiliki angka mortalitas yang cukup tinggi dikarenakan gejalanya yang tidak spesifik, sering ditemukan pada stadium lanjut, dan belum adanya metode deteksi dini yang sudah terbukti. Untuk menilai keberhasilan terapi penyintas kanker ovarium, tidak hanya dinilai dari aspek klinis tetapi juga dinilai dari kualitas hidup penyintas kanker ovarium yang penilaiannya berdasarkan skala fungsional dan skala gejala dalam kuesioner EORTC QLQ C30 dan EORTC QLQ OV28. Metode: Penelitian ini menggunakan desain penelitian cross sectional, menggunakan data primer dari hasil wawancara dengan kuesioner EORTC QLQ C30 dan EORTC QLQ OV28 serta data sekunder yang berasal dari rekam medik di RSUP Haji Adam Malik Medan tahun 2017 - 2018. Sampel penelitian dipilih dengan metode total sampling dari seluruh data rekam medik yang memenuhi kriteria penelitian.   Hasil: Hasil penelitian ini didapatkan kualitas hidup global penyintas kanker ovarium 89.36% adalah baik, dan 10.64% adalah sedang serta tidak ada yang memiliki kualitas hidup buruk. Namun, didapatkan adanya gangguan pada skala fungsional berupa: fungsi emosional, fungsi kognitif, fungsi seksual, dan sikap terhadap penyakit, serta adanya permasalahan pada skala gejala berupa: kelelahan, nyeri, neuropati perifer, dan gejala menopause. Didapatkan juga tidak ada hubungan karakteristik usia, jenis histopatologis, stadium, lama terapi dengan kualitas hidup penyintas kanker ovarium, namun terdapat hubungan antara jenis terapi dengan kualitas hidup penyintas kanker ovarium. Kesimpulan: Kualitas hidup penyintas kanker ovarium secara global adalah baik. Kata Kunci: Kualitas Hidup, Penyintas Kanker Ovarium, EORTC QLQ C-30, EORTC QLQ     OV-28   Abstract Background: Ovarian cancer has a high mortality rate due to nonspecific symptoms, often found at an advanced stage, and also the absence of proven early detection methods. To assess the success of ovarian cancer survivors therapy, it is not only assessed from the clinical aspect but also from the quality of life of ovarian cancer survivors which is based on the functional and symptom scale in the EORTC QLQ C30 and EORTC QLQ OV28 questionnaires.  Methods: This study used a cross-sectional study design, using primary data from interviews with the survivors based on the questionnaire EORTC QLQ C30 and EORTC QLQ OV28 as well as secondary data derived from medical records at Haji Adam Malik General Hospital Medan in 2017 - 2018. The research sample was used with a total sampling method from all medical record data that fulfill the research criteria.  Result: The quality of life of ovarian cancer survivors is generally good (89.36%), meanwhile the rest is moderate (10.64%) without the poor quality of life. However, there are disorders on the functional scale in the form of emotional function, cognitive function, sexual function, and attitude toward disease. Likewise on the scale of symptoms, there are problems including: fatigue, pain, peripheral neuropathy, and menopausal symptoms.  Conclusion: The quality of life of ovarian cancer survivors globally is good. Keywords: Quality of Life, Ovarian Cancer Survivors, EORTC QLQ C-30, EORTC QLQ OV-28  

scholarly journals AVALIAÇÃO DA QUALIDADE DE VIDA EM PACIENTES ONCOLÓGICOS DE UM CENTRO DE ONCOLOGIA, BELÉM- PA

2020 ◽  
pp. 1-9
Author(s):  
Amarildo Ferreira Moreira Junior ◽  
Anne Louise de Souza Soares ◽  
Michelen Silva de Souza ◽  
Wiviane Maria Torres de Matos Freitas
Keyword(s):  
C 30 ◽  
Eortc Qlq

O câncer é uma doença multifatorial, crônica que representa a segunda causa mais comum de mortes no mundo. A pesquisa objetivou avaliar a qualidade de vida de pacientes oncológicos de uma clínica em Belém – PA. Trata-se de um estudo quanti-qualitativo, de delineamento observacional, do tipo transversal e descritivo. Os autores aplicaram uma ficha, de autoria própria, para identificação do perfil clínico e epidemiológico e o Questionário EORTC QLQ C- 30. Como resultados, destaca-se a predominância do sexo feminino (73,91%), média de 57 anos de idade, a maioria não possui hábitos de etilismo (78,26%) e tabagismo (69,57%). No que se refere à Função Física, a Função Cognitiva e a Função Social obtiveram valores médios acima de 70, indicando nível regular a satisfatório, sendo a função emocional a mais prejudicada. O estudo identificou que o tratamento implicou em dificuldade financeira para as pacientes (81,16), assim como provocou sintomas como diarreia (89,85), dispneia (78,26), náusea e vômito (77,53). Segundo o instrumento EORTC QLQ C- 30 os pacientes apresentam baixa qualidade de vida (31,88). O questionário mostrou-se um importante instrumento no cuidado do paciente oncológico, para a avaliação do desempenho físico, psicológico e social do paciente com câncer, permitindo inferir os reais resultados do tratamento.

scholarly journals Reliability and Validity of Amharic Version of EORTC QLQ-C 30 Questionnaire among Gynecological Cancer Patients in Ethiopia

PLoS ONE ◽  
2016 ◽  
Vol 11 (6) ◽  
pp. e0157359 ◽  
Author(s):  
Birhanu Abera Ayana ◽  
Shiferaw Negash ◽  
Lukman Yusuf ◽  
Wendemagegnhu Tigeneh ◽  
Demewoz Haile
Keyword(s):  
Cancer Patients ◽  
Gynecological Cancer ◽  
Reliability And Validity ◽  
C 30 ◽  
Eortc Qlq

Quality of life (QoL) improvements in 1,464 patients (pts) with metastatic breast cancer (MBC) receiving capecitabine (X) in Brazil: Updated results from a large pt cohort, including analysis as a function of pts’ ECOG PS

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 8599-8599 ◽  
Author(s):  
C. Oliveira ◽  
R. Ribeiro ◽  
J. G. Segalla ◽  
S. Tessaro ◽  
S. Cabral ◽  
...  
Keyword(s):  
Repeated Measures ◽  
Linear Models ◽  
Single Agent ◽  
Metastatic Breast ◽  
Future Perspective ◽  
Highly Active ◽  
C 30 ◽  
Eortc Qlq ◽  
Almost All ◽  
Ecog Ps

8599 Background: The oral fluoropyrimidine capecitabine is highly active and well tolerated as single-agent therapy and extends survival when added to docetaxel in pretreated MBC. QoL data would enhance understanding of X’s pt benefits. Methods: QoL was evaluated in women with anthracycline ± taxane-pretreated MBC while receiving X (baseline, before cycle 1, at weeks 7 and 13, and at treatment end) using EORTC QLQ C-30 (v3.0) and BR-23 questionnaires. We used linear models with repeated measures (generalized estimating questions technique) and SAS (v8.2) to determine improvement, stabilization or worsening of QoL scores from week 7 onwards. Each questionnaire item was analyzed as a function of pts’ ECOG status before first cycle and the evaluation periods. Results: Baseline characteristics of the 1,464 evaluable pts were: median age 54 years (range 22–92); 42% had ECOG 0. As expected, pts with worse initial PS (ECOG ≥2) had lower mean scores during treatment. Regardless of baseline ECOG score, X therapy was associated with significant (p<0.0001 unless stated) improvements in pts’ perception of: role functioning (p=0.001), pain, nausea/vomiting, fatigue, constipation, emotional functioning, and global health status. Capecitabine was also associated with significant improvements in pts’ perception of systemic therapy side effects (p<0.0001), breast symptoms (p<0.0001), arm symptoms (p=0.0047), hair loss (p<0.0001), and future perspective (p<0.0001). Conclusions: Pts receiving X had substantial improvements in almost all functional and symptomatic QoL domains. These findings highlight the importance of considering QoL and other measurable benefits of oral treatments alongside well-established measures of clinical evaluation in pts with metastatic disease. The QoL benefits, together with other proven clinical outcomes, suggest that early use of X in MBC would be of benefit to pts. No significant financial relationships to disclose.

Health-related quality of life of of women with breast cancer undergoing chemotherapy in the northern region of Brazil.

2015 ◽  
Vol 33 (28_suppl) ◽  
pp. 92-92
Author(s):  
Namie Okino Sawada ◽  
Mary Elizabeth de Santana ◽  
Helena Megumi Sonobe
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Rural Areas ◽  
Health Related Quality ◽  
European Organization ◽  
Related Quality ◽  
Health Related ◽  
C 30 ◽  
Eortc Qlq

92 Background: In Brazil, the estimate for the year 2015 is approximately 576,000 new cases of cancer. Breast cancer is the most common in Brazilian women and the state of Pará is the first with the highest incidence of breast cancer in northern Brazil. The high incidence and changes caused by treatment and own illness as the disturbances in body image, functional, emotional and social changes cause fear in women, as well as disrupting daily activities and impact the health-Related Quality of Life (HRQOL). Improving HRQOL is an important goal so the evaluation of HRQoL of these patients is of interest to health professionals, as they provide information that help in planning treatment and rehabilitation. The objective is to evaluate the HRQoL of patients with breast cancer in chemotherapy treatment. Methods: It is a cross-sectional study with quantitative exploratory design. This place was a public hospital in the city of Belém do Pará, Women were included with breast cancer, over eighteen years old and excluded those with cognitive problems and metastases. The European Organization for Research and Treatment of Cancer Quality of Life (EORTC QLQ C 30) and Questionnaire Breast Cancer Module (QLQ BR23) have been administrated. The project was approved by the Ethics Committee and were respected the resolution 466/2012 CNS / MS. Results: The sample consisted of 89 women with breast cancer undergoing chemotherapy, most in the age group over 40, mulatto, married, fundamental level of education, domestic load, Catholic religion, live in rural areas with incomes of one to two minimum salaries. The EORTC QLQ C 30 showed that the average QOL was 75.56, and the most impaired functions were physical (M = 65.62) and role performance (M = 58.61) and the most frequent symptoms were diarrhea, constipation, dyspnea, nausea and vomiting, fatigue, pain and loss of appetite. EORTC BR23 demonstrated functional scale (M = 49.95) and symptoms scale (M = 33.00). Conclusions: The results show that the side effects of chemotherapy affect the physical and functional function and consequently HRQoL of these patients.

scholarly journals EP-1142: EORTC QLQ C-30 scores evolution in stage I-III breast cancer patients during sequential treatment

2017 ◽  
Vol 123 ◽  
pp. S621-S622
Author(s):  
A. Vila ◽  
J. Perez de Olaguer ◽  
P. Gallego ◽  
G. Carrera ◽  
A. Pedro
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Stage I ◽  
Sequential Treatment ◽  
Breast Cancer Patients ◽  
C 30 ◽  
Eortc Qlq

scholarly journals Cancer in the Adolescent and Young Adults (AYA) and Children: A Comprehensive Analysis of the Epidemiology and Psychosocial Morbidity in the Indian Population

2021 ◽  
Author(s):  
Bhupesh Guleria ◽  
S. Viswanath ◽  
Dharmesh Soneji ◽  
Rajan Kapoor ◽  
Prerna Guleria ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Life Questionnaire ◽  
Solid Organ ◽  
Children With Cancer ◽  
Adolescent And Young Adults ◽  
C 30 ◽  
Eortc Qlq ◽  
Psychosocial Morbidity

Aims Adolescent and young adults (AYAs), children with cancer, and their guardians have unique psychosocial morbidities adversely effecting quality of life (QOL). This is measurable using patented tools. We analyzed epidemiological and clinicopathological patterns of solid organ cancers in this subgroup. We also assessed psychosocial morbidity and changes in QOL faced by them. Methods All patients aged 2 to 39 years, newly diagnosed with cancer from April 2017 to March 2019 were included. Clinical history, diagnosis, staging, treatment, outcomes, and follow-up were recorded. The National Comprehensive Cancer Network (NCCN) distress thermometer and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ C-30) were used to assess psychosocial morbidity of AYAs, children ≥ 12 years, and parents of children < 12 years. Pediatric Quality of Life Inventory (Peds QL) version 3.0 was used for children < 12 years. Data was analyzed using descriptive statistics. Results A total of 571 patients (512 AYAs, 59 children) were enrolled. Median age was 30 years with male predominance (58.1%). Most cases (98.6%) were absent from school or work. Carcinoma breast was the most common in females (29.3%) and non-Hodgkin lymphoma in males (12.6%). 91.06% had overall NCCN distress score ≥ 4. Also, 73.81 and 79.49% had “quite a bit” or “very much” responses on functional and symptom scales, respectively, in EORTC QLQ C-30 questionnaire. Peds QL version 3.0 revealed total score ranging from 276 to 523 for each patient. Conclusion AYAs and children with cancer are extremely vulnerable to psychological stress and morbidity. Use of well-established tools help in assessing their mental status and timely psychiatric referral can be initiated.

scholarly journals Validación para utilización en Colombia de la escala EORTC QLQ C-30 para evaluación de la calidad de vida de los pacientes con cáncer

2020 ◽  
Vol 24 (2) ◽  
pp. 61-71
Author(s):  
Ricardo Sánchez Pedraza ◽  
Adriana Valderamar
Keyword(s):  
Calidad De Vida ◽  
Palabras Clave ◽  
C 30 ◽  
Eortc Qlq

Objetivo: Validar la versión colombiana de la escala EORTC QLQC-30 para medir calidad de vida en pacientes con diagnóstico de cáncer en Colombia. Métodos: La validez de la escala se determinó usando métodos de análisis factorial  exploratorio y confirmatorio. Adicionalmente, para medir la validez de criterio concurrente se utilizaron análisis de correlación entre dominios de las escalas EORTC QLQC-30 y FACIT-G. Para evaluar la confiabilidad se efectuaron análisis de consistencia interna (se usaron coeficientes Alfa de Cronbach, Omega de McDonald y GLB), así como análisis de medidas repetidas (confiabilidad test-retest). Resultados: En el estudio se incluyó un total de 486 pacientes ubicados en el Instituto Nacional de Cancerología en Colombia. Tanto el modelo estándar de 14 dominios como una solución empírica con cinco dominios (Físico, Psicológico, Debilidad, Socioeconómico y Puntaje Global) demostraron tener una adecuada representatividad del constructo. La correlación entre dominios del EORTC QLQC-30 y del FACT-G mostró valores bajos en el dominio relacionado con funcionamiento social. La correlación entre medidas repetidas tuvo valores de correlación-concordancia entre 0,51 y 0,8; los límites de acuerdo de Bland y Altman estuvieron entre -38 y 43 alrededor de un valor esperado de cero. Los valores de Alfa de Cronbach, GLB y Omega de McDonald tuvieron valores de 0,94 – 0,96 y 0,93 respectivamente. Conclusión: La escala EORTC QLQC-30 es un instrumento válido y confiable para medir calidad de vida en pacientes con cáncer en Colombia. Palabras clave: Calidad de vida. Neoplasia. Estudios de Validación. Confiabilidad. Validez.

scholarly journals Hubungan antara Faktor Klinikohistopatologi dan Kualitas Hidup Pasien Kanker Endometrium Pasca Operasi di RSUP Dr.Sardjito Yogyakarta Menggunakan Modul Kuesioner EORTC QLQ-C30 dan EN 24

2021 ◽  
Vol 8 (1) ◽  
pp. 23
Author(s):  
Dini Mahrani ◽  
Ahsanudin Attamimi ◽  
Ardhanu Kusumanto
Keyword(s):  
Quality Of Life ◽  
Cancer Research ◽  
Endometrial Cancer ◽  
Therapeutic Success ◽  
Cross Sectional ◽  
Clinical Patient ◽  
The World ◽  
C 30 ◽  
Eortc Qlq

Background: According to data from the "Endometrial Cancer Report" by the World Cancer Research Fund and the American Institute for Cancer Research (WCRFI), endometrial cancer is the sixth most common malignancy in the world and is the largest cancer in female organs, after cervical cancer. This incidence is increasing every year, it is predicted to increase about 5% of new cases each year. The main prognostic factors of endometrial cancer are determined by the histological type, stage, degree, differentiation of the tumor, invasive myometrial level and increase in lympho-vascular invasion. In addition to determining the histopathological factors, the prognosis is also determined from the clinical patient. Several studies have shown certain clinical factors also improve the condition and prognosis of the disease. Prognosis of this disease with the quality of life of patients becomes an interesting topic to discuss. Besides that quality of life is also a measure of therapeutic success. The better the prognosis of a disease, the better the quality of life, the higher the success rate of therapy (Greimel, 2010).Objective: To know correlation between clinicohistopathological and quality of life in patients with endometrial cancer after undergoing surgery at Sardjito Hospital, Yogyakarta.Method: The research is analytic with cross sectional approach. Patients with endometrial cancer who have undergone total hysterectomy and bisalpingoophorectomy surgery are assessed for their quality of life through interviews and filling out questionnaires in the EORTC QLQ-C 30 and QLQ-EN 24 modules.Results and Discussion: This study, most people with endometrial cancer aged 55-65 years were 34 people (42%) and diagnosed after menopause with a range of age >55 years as many as 43 people (53.1%). This study cannot prove the hypothesis that age, parity, body mass index, type of histopathology and KGB involvement have a relationship with the quality of life of cancer patients (p >0.05). But in contrast to the stage of early cancer (OR 3.17, p=0.044 (CI 95% 1.03-9.75)) and good and moderate differentiation (OR 4.471, p=0.023 (CI 95% 1.23-16.24)) have a significant relationship with quality of life.Conclusion: Clinicohistopathological factors (cancer stage and tumor differentiation) have a correlation with the quality of life at patients with postoperative endometrial cancer in  Sardjito Hospital Keywords: Endometrial cancer; clinicohistopathological factors; quality of life

scholarly journals Reconstructive Surgery in Soft Tissue Sarcomas—Long-Term Outcome and Quality of Life

2017 ◽  
Vol 102 (11-12) ◽  
pp. 480-488
Author(s):  
Reiner Wirbel ◽  
Steffen Weber ◽  
Angela Olinger ◽  
Wolf Mutschler ◽  
Tim Pohlemann
Keyword(s):  
Quality Of Life ◽  
Functional Outcome ◽  
Reconstructive Surgery ◽  
Soft Tissue Sarcomas ◽  
Tumor Stage ◽  
Stage Ii ◽  
C 30 ◽  
Eortc Qlq

The long-term oncological and functional outcome including quality of life should be evaluated in soft tissue sarcomas (STS). The need for reconstructive surgery with possible influence on the results should also be analyzed. Tumor stage mainly influences the prognosis of STS. Advances in reconstructive surgery mostly allow limb salvage. Limited information exists about functional outcome and life quality. A total of 86 patients (51 men, 35 women, mean age 50.5 years) with a minimum follow-up of 10 years were analyzed. We determined the oncological outcome (local recurrences, metastases, overall survival) of tumors at varying stages: stage I (n = 30), stage II (n = 52), and stage III (n = 4). Functional outcome and quality of life of the survivors were measured using the Musculoskeletal Tumor Society (MSTS) criteria and the EORTC-QLQ-C-30 (European Organisation for Research and Treatment of Cancer-Quality of Life-Questionnaire-Core-30 module) questionnaire. Tumor stage influenced the survival and the development of metastases. Survival rates were 89.5 and 88% after 5 and 10 years in stage I, and 56.5 and 49% in stage II tumors. Surgical margin influenced the development of local recurrence. Reconstructive procedures were necessary in 27 patients. After a median follow-up of 144 months, 36 patients were dead: 29 of their malignancy and 7 of other diseases. Fifty long-term survivors presented good results for MSTS (mean score: 82.4) and EORTC-QLQ-C-30 (mean score: 79.8), the results were independent on the need of reconstructive surgery. In stage II STS, the survival drops even after 5 years. The surgical treatment of STS requires the knowledge of different reconstructive techniques; functional results and quality of life are not compromised by the need for reconstructive surgery.

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